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4-Hydroxyisophthalic acid

Product Name
4-Hydroxyisophthalic acid
CAS No.
636-46-4
Chemical Name
4-Hydroxyisophthalic acid
Synonyms
4-hipa;NSC 2445;Eupirina;Aspirin IMpurity B;Aspirin Impurity 2;RARECHEM AL BE 0104;4-Hydroxyisophthalic;Aspirin EP IMpurity B;4-hydroxy-isophthalicaci;4-HYDROXYISOPHTHALIC ACID
CBNumber
CB4234715
Molecular Formula
C8H6O5
Formula Weight
182.13
MOL File
636-46-4.mol
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4-Hydroxyisophthalic acid Property

Melting point:
>300°C
Boiling point:
310 C
Density 
1.4411 (rough estimate)
refractive index 
1.5690 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
solid
pka
2?+-.0.10(Predicted)
color 
White to Pale Purple
Water Solubility 
0.3g/L(24 ºC)
Merck 
14,4827
Stability:
Hygroscopic
CAS DataBase Reference
636-46-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-22-36/38
Safety Statements 
26-36/37/39-36-39-6
WGK Germany 
3
RTECS 
NT2544000
HS Code 
29182900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
797057
Product name
4-Hydroxyisophthalic acid
Purity
95%
Packaging
250mg
Price
$135
Updated
2024/03/01
Sigma-Aldrich
Product number
1609024
Product name
Salicylic acid Related Compound B
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
100mg
Price
$1490
Updated
2024/03/01
TCI Chemical
Product number
H0257
Product name
4-Hydroxyisophthalic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
H0257
Product name
4-Hydroxyisophthalic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$273
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0000405
Product name
Salicylic acid impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000405
Price
$153
Updated
2024/03/01
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4-Hydroxyisophthalic acid Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

4-Hydroxyisophthalic acid has been proposed as an improvement over aspirin. An impurity of Acetylsalicylic acid (A187780). Acetylsalicylic Acid Impurity B; Aspirin Impurity B

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Hydroxyisophthalic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxyisophthalic acid Suppliers

Americas 1 Belgium 1 Canada 2 China 150 Europe 1 Germany 4 India 33 Japan 3 Mexico 1 Norway 1 Switzerland 1 Ukraine 1 United Kingdom 19 United States 46 Global 264
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from 4-Hydroxyisophthalic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Hydroxyisophthalic acid 636-46-4
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16
Hebei Mojin Biotechnology Co., Ltd
Product
4-Hydroxyisophthalic acid 636-46-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-27
Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Hydroxyisophthalic acid 636-46-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-14

636-46-4, 4-Hydroxyisophthalic acidRelated Search:

SALICYLIC ACID, IMP. B (EP): 4-HYDROXYISOPHTHALIC ACID MM(CRM STANDARD) 2'-Hydroxy-3-phenylpropiophenone Isophthalic acid 5-Aminoisophthalic acid Methylparaben Isopropylparaben Butylparaben 3-Hydroxybenzoic acid CHLOROPHOSPHONAZO III Terephthalic acid 4-Hydroxyphthalic acid 4-Hydroxybenzoic acid DIMETHYL 4-HYDROXYISOPHTHALATE HYDROXYISOPHTHALIC ACID, 5-,5-HYDROXYISOPHTHALIC ACID 4-Methoxyisophthalic acid 5-HYDROXYBENZENE-1,2,4-TRICARBOXYLIC ACID 2-Hydroxy-m-phthalic acid 5-HYDROXYISOPHTHALIC ACID DIMETHYL,Dimethyl 5-hydroxybenzene-1,3-dicarboxylate~5-Hydroxyisophthalic acid dimethyl ester,5-HYDROXYISOPHTHALIC ACID DIMETHYL ESTER

  • HYDROXYISOPHTHALIC ACID, 4-
  • 4-HYDROXYISOPHTHALIC ACID
  • 4-HYDROXYBENZENE-1,3-DICARBOXYLIC ACID
  • 4-HYDROXY-1,3-BENZENEDECARBOXYLIC ACID
  • 4-HYDROXY-1,3-BENZENEDICARBOXYLIC ACID
  • ACETYLSALISYLIC ACID IMP B
  • NSC 2445
  • Aspirin EP IMpurity B
  • Aspirin IMpurity B
  • Acetylsalicylic Acid IMpurity B (Aspirin IMpurity B)
  • 1,3-Benzenedicarboxylicacid, 4-hydroxy-
  • Aspirin Impurity 2
  • 4-Hydroxyisophthalic Acid(Salicylic Acid RCB)
  • Acetylsalicylic Acid EP Impurity B
  • Acetylsalicylic Acid Impurity 2（Acetylsalicylic Acid EP Impurity B）
  • 4-hipa
  • 4-hydroxy-3-benzenedicarboxylicacid
  • 4-hydroxy-isophthalicaci
  • RARECHEM AL BE 0104
  • 4-HYDROYLISOPHTHALIC ACID
  • 4-Hydroxyisophthalic
  • 4-Hydroxy Isophthallic Acid
  • 4-Hydroxy-m-phthalic acid
  • Eupirina
  • 4-Hydroxyisophthalic acid,98%
  • Salicylic Acid Related Compound B (100 mg) (4-hydroxyisophthalic acid)
  • 4-Hydroxyisophthalic acid (4-Hydroxybenzene-1,3-dicarboxylic acid)
  • Salicylic Acid EP Impurityuriy B
  • 4-Hydroxyisophthalic acid(4-HIPA)
  • Acetylsalicylic Acid EP Impurity B (Aspirin Impurity B)
  • 4-HydroxyisophthalicAcid&gt
  • Salicylic acid impurity B CRS
  • Acetylsalicylic Acid Impurity B
  • 4-Hydroxy Isopthalic acid
  • Mesalazine Impurity(4-hydroxylphthallic acid)
  • Acetylsalicylic Acid EP Impurity B (4-Hydroxyisophthalic Acid)
  • Aspirin Impurity BQ: What is Aspirin Impurity B Q: What is the CAS Number of Aspirin Impurity B Q: What is the storage condition of Aspirin Impurity B Q: What are the applications of Aspirin Impurity B
  • Salicylic Acid Related Compound B (4-hydroxyisophthalic acid) (1609024)
  • Salicylic Acid USP Related Compound B
  • Aspirin (Acetylsalicylic Acid) EP Impurity B
  • Salicylic Acid EP Impurity B
  • Acetylsalicylic Acid EP Impurity B (Salicylic Acid USP Related Compound B)
  • 4-Hydroxyisophthalicacid(AspirinImpurity)
  • 636-46-4
  • Aromatics, Impurities
  • API intermediates
  • Phthalic Acids, Esters and Derivatives
  • Aromatics
  • Impurities