5-Hydroxyisophthalic acid

Product Name: 5-Hydroxyisophthalic acid
CAS No.: 618-83-7
Chemical Name: 5-Hydroxyisophthalic acid
Synonyms: OHIPA;5-HIPA;5-HydroxyisophthaL;3,5-Dicarboxyphenol;5-Hydroxy Isophthalate;5-hydroxy-isophthalicaci;5-HYDROXYISOPTHALIC ACID;5-HYDROXYISOPHTHALIC ACID;HYDROXYISOPHTHALIC-5 ACID;5-Hydroxy-m-phthalic acid
CBNumber: CB4412793
Molecular Formula: C8H6O5
Formula Weight: 182.13
MOL File: 618-83-7.mol

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5-Hydroxyisophthalic acid Property

Melting point:: 298-302 °C (lit.)
Boiling point:: 235.5°C (rough estimate)
Density: 1.3293 (rough estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.4330 (estimate)
storage temp.: Store below +30°C.
solubility: 0.6g/l
form: Powder
pka: 3.41±0.10(Predicted)
color: White to slightly yellow
PH: <7 (H2O, 20℃)
Water Solubility: 0.6g/L(15 ºC)
BRN: 2693561
InChI: 1S/C8H6O5/c9-6-2-4(7(10)11)1-5(3-6)8(12)13/h1-3,9H,(H,10,11)(H,12,13)
InChIKey: QNVNLUSHGRBCLO-UHFFFAOYSA-N
Dissociation constant: 0-0 at 23℃
CAS DataBase Reference: 618-83-7(CAS DataBase Reference)
EPA Substance Registry System: 5-Hydoxyisophthalic acid (618-83-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-24/25-36
WGK Germany: 2
RTECS: CZ4280000
TSCA: TSCA listed
HS Code: 29182990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 311278
Product name: 5-Hydroxyisophthalic acid
Purity: 97%
Packaging: 100g
Price: $87.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.40013
Product name: 5-Hydroxyisophthalic acid
Purity: for synthesis
Packaging: 50g
Price: $90.5
Updated: 2022/05/15

TCI Chemical

Product number: H0794
Product name: 5-Hydroxyisophthalic Acid
Purity: >97.0%(T)
Packaging: 25g
Price: $64
Updated: 2025/07/31

TCI Chemical

Product number: H0794
Product name: 5-Hydroxyisophthalic Acid
Purity: >97.0%(T)
Packaging: 500g
Price: $622
Updated: 2025/07/31

TRC

Product number: H943485
Product name: 5-Hydroxyisophthalic Acid
Packaging: 10g
Price: $85
Updated: 2021/12/16

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5-Hydroxyisophthalic acid Chemical Properties,Usage,Production

Chemical Properties

white to slightly yellow powder

Uses

5-Hydroxyisophthalic Acid is used as a reagent in the synthesis of silver carboxylate metal organic framework (MOF) complexes. 5-Hydroxyisophthalic Acid is also used as the starting material in the synthesis of N,NтАЩ-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide (B426310); a compound related to Ioversol( I737000) which is a nonionic, low osmolality, radiographic contrast agent.

General Description

The hydrothermal reaction of 5-hydroxyisophthalic acid, Co(II)/Cu(II) and dipyridophenazine, that forms two 3D chiral coordination polymers, was studied.

Synthesis

13036-02-7

618-83-7

The general procedure for the synthesis of 5-hydroxyisophthalic acid from dimethyl 5-hydroxyisophthalate was as follows: dimethyl 5-hydroxyisophthalate (40 g, 19.03 mmol) was dissolved in THF (10 mL), followed by the addition of aqueous lithium hydroxide (20 mL, 2 M). The reaction mixture was stirred at 40 °C overnight. Upon completion of the reaction, THF was removed by distillation under reduced pressure. the pH of the remaining aqueous solution was adjusted to about 2 with 6N hydrochloric acid to precipitate the product. The precipitated 5-hydroxyisophthalic acid was collected by filtration and dried in a vacuum oven to give 20 g of white solid product in 58% yield.

References

[1] Patent: WO2010/78449, 2010, A2. Location in patent: Page/Page column 317

5-Hydroxyisophthalic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Hydroxyisophthalic acid Suppliers

Americas 1 Belgium 3 China 261 Czech Republic 3 Europe 4 Finland 1 France 1 Germany 8 India 18 Italy 1 Japan 10 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 2 United Kingdom 12 United States 40 Global 369

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View Lastest Price from 5-Hydroxyisophthalic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 5-Hydroxyisophthalic acid 618-83-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-05

Shaanxi Dideu New Materials Co. Ltd

Product: 5-Hydroxyisophthalic acid 618-83-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 10000KGS
Release date: 2025-02-18

Wuhan Boyuan Import & Export Co., LTD

Product: 5-Hydroxyisophthalic acid 618-83-7
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000tons
Release date: 2023-06-06

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OHIPA

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5-hydroxy-isophthalicaci

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5-Hydroxyisophthalic acid high quality(618-83-7)

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sym-Hydroxy-iso-phthalicacid

5-Hydroxy-m-phthalic acid

5-Hydroxy-1,3-benzenedicarboxy

5-HYDROXYISOPHTHHALIC ACID

5-Hydroxy Isophthalate

5-Hydroxy isophtalic acid

3,5-Dicarboxyphenol

5-Hydroxyisophthalic acid, 99% 100GR

5-Hydroxyisophthalic acid, 99% 25GR

5-Hydroxyisophthalic acid, 99% 500GR

5-Hydroxybenzene-1,3-dicarboxylic acid, 3,5-Dicarboxyphenol

5- hydroxybenzene between two forMic acid

5-HydroxyisophthalicAcid&gt

5-HYDROXYISOPHTHALIC ACID FOR SYNTHESIS

1,3-Benzenedicarboxylic acid, 5-hydroxy-

5-HYDROXYISOPHTHALIC ACID (5-HIPA)

618-83-7

C8H6O5

HOC6H313CO2H2

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