ChemicalBook > CAS DataBase List > 4-Hydroxyisophthalic acid

4-Hydroxyisophthalic acid

Product Name
4-Hydroxyisophthalic acid
CAS No.
636-46-4
Chemical Name
4-Hydroxyisophthalic acid
Synonyms
4-hipa;NSC 2445;Eupirina;Aspirin IMpurity B;Aspirin Impurity 2;RARECHEM AL BE 0104;4-Hydroxyisophthalic;Aspirin EP IMpurity B;4-hydroxy-isophthalicaci;4-HYDROXYISOPHTHALIC ACID
CBNumber
CB4234715
Molecular Formula
C8H6O5
Formula Weight
182.13
MOL File
636-46-4.mol
More
Less

4-Hydroxyisophthalic acid Property

Melting point:
>300°C
Boiling point:
310 C
Density 
1.4411 (rough estimate)
refractive index 
1.5690 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
solid
pka
2?+-.0.10(Predicted)
color 
White to Pale Purple
Water Solubility 
0.3g/L(24 ºC)
Merck 
14,4827
Stability:
Hygroscopic
CAS DataBase Reference
636-46-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-22-36/38
Safety Statements 
26-36/37/39-36-39-6
WGK Germany 
3
RTECS 
NT2544000
HS Code 
29182900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
797057
Product name
4-Hydroxyisophthalic acid
Purity
95%
Packaging
250mg
Price
$135
Updated
2024/03/01
Sigma-Aldrich
Product number
1609024
Product name
Salicylic acid Related Compound B
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
100mg
Price
$1490
Updated
2024/03/01
TCI Chemical
Product number
H0257
Product name
4-Hydroxyisophthalic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
H0257
Product name
4-Hydroxyisophthalic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$273
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0000405
Product name
Salicylic acid impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000405
Price
$153
Updated
2024/03/01
More
Less

4-Hydroxyisophthalic acid Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

4-Hydroxyisophthalic acid has been proposed as an improvement over aspirin. An impurity of Acetylsalicylic acid (A187780). Acetylsalicylic Acid Impurity B; Aspirin Impurity B

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Hydroxyisophthalic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Hydroxyisophthalic acid Suppliers

Americas 1 Belgium 1 Canada 2 China 150 Europe 1 Germany 4 India 33 Japan 3 Mexico 1 Norway 1 Switzerland 1 Ukraine 1 United Kingdom 19 United States 46 Global 264
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18089
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-021-64543801 13764082696
Email
2355241799@qq.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Nanjing King-pharm Co.,LTD.
Tel
025-58748998 19951791336
Email
elsa@chemsigma.com
Country
China
ProdList
117
Advantage
65
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4968
Advantage
50
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9449
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7854
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9352
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17993
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13359
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Shanghai Na Qian Chemical Technology Co. Ltd.
Tel
13598610367
Fax
QQ:2468833170
Email
2841375912@qq.com
Country
China
ProdList
2786
Advantage
52
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5936
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.
Tel
027-65388397 18164111589
Fax
027-65388397
Email
3321478047@qq.com
Country
China
ProdList
1997
Advantage
55
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1748
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
Wuhan Greatwall chemical Co,.LTD
Tel
400-027-6116 18086000087
Fax
QQ: 2680733325
Email
sales@chemgreatwall.com
Country
China
ProdList
1561
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
More
Less

View Lastest Price from 4-Hydroxyisophthalic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Hydroxyisophthalic acid 636-46-4
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16
Hebei Mojin Biotechnology Co., Ltd
Product
4-Hydroxyisophthalic acid 636-46-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-27
Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Hydroxyisophthalic acid 636-46-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-14

636-46-4, 4-Hydroxyisophthalic acidRelated Search:

SALICYLIC ACID, IMP. B (EP): 4-HYDROXYISOPHTHALIC ACID MM(CRM STANDARD) 2'-Hydroxy-3-phenylpropiophenone Isophthalic acid 5-Aminoisophthalic acid Methylparaben Isopropylparaben Butylparaben 3-Hydroxybenzoic acid CHLOROPHOSPHONAZO III Terephthalic acid 4-Hydroxyphthalic acid 4-Hydroxybenzoic acid DIMETHYL 4-HYDROXYISOPHTHALATE HYDROXYISOPHTHALIC ACID, 5-,5-HYDROXYISOPHTHALIC ACID 4-Methoxyisophthalic acid 5-HYDROXYBENZENE-1,2,4-TRICARBOXYLIC ACID 2-Hydroxy-m-phthalic acid 5-HYDROXYISOPHTHALIC ACID DIMETHYL,Dimethyl 5-hydroxybenzene-1,3-dicarboxylate~5-Hydroxyisophthalic acid dimethyl ester,5-HYDROXYISOPHTHALIC ACID DIMETHYL ESTER

  • HYDROXYISOPHTHALIC ACID, 4-
  • 4-HYDROXYISOPHTHALIC ACID
  • 4-HYDROXYBENZENE-1,3-DICARBOXYLIC ACID
  • 4-HYDROXY-1,3-BENZENEDECARBOXYLIC ACID
  • 4-HYDROXY-1,3-BENZENEDICARBOXYLIC ACID
  • ACETYLSALISYLIC ACID IMP B
  • NSC 2445
  • Aspirin EP IMpurity B
  • Aspirin IMpurity B
  • Acetylsalicylic Acid IMpurity B (Aspirin IMpurity B)
  • 1,3-Benzenedicarboxylicacid, 4-hydroxy-
  • Aspirin Impurity 2
  • 4-Hydroxyisophthalic Acid(Salicylic Acid RCB)
  • Acetylsalicylic Acid EP Impurity B
  • Acetylsalicylic Acid Impurity 2（Acetylsalicylic Acid EP Impurity B）
  • 4-hipa
  • 4-hydroxy-3-benzenedicarboxylicacid
  • 4-hydroxy-isophthalicaci
  • RARECHEM AL BE 0104
  • 4-HYDROYLISOPHTHALIC ACID
  • 4-Hydroxyisophthalic
  • 4-Hydroxy Isophthallic Acid
  • 4-Hydroxy-m-phthalic acid
  • Eupirina
  • 4-Hydroxyisophthalic acid,98%
  • Salicylic Acid Related Compound B (100 mg) (4-hydroxyisophthalic acid)
  • 4-Hydroxyisophthalic acid (4-Hydroxybenzene-1,3-dicarboxylic acid)
  • Salicylic Acid EP Impurityuriy B
  • 4-Hydroxyisophthalic acid(4-HIPA)
  • Acetylsalicylic Acid EP Impurity B (Aspirin Impurity B)
  • 4-HydroxyisophthalicAcid&gt
  • Salicylic acid impurity B CRS
  • Acetylsalicylic Acid Impurity B
  • 4-Hydroxy Isopthalic acid
  • Mesalazine Impurity(4-hydroxylphthallic acid)
  • Acetylsalicylic Acid EP Impurity B (4-Hydroxyisophthalic Acid)
  • Aspirin Impurity BQ: What is Aspirin Impurity B Q: What is the CAS Number of Aspirin Impurity B Q: What is the storage condition of Aspirin Impurity B Q: What are the applications of Aspirin Impurity B
  • Salicylic Acid Related Compound B (4-hydroxyisophthalic acid) (1609024)
  • Salicylic Acid USP Related Compound B
  • Aspirin (Acetylsalicylic Acid) EP Impurity B
  • Salicylic Acid EP Impurity B
  • Acetylsalicylic Acid EP Impurity B (Salicylic Acid USP Related Compound B)
  • 4-Hydroxyisophthalicacid(AspirinImpurity)
  • 636-46-4
  • Aromatics, Impurities
  • API intermediates
  • Phthalic Acids, Esters and Derivatives
  • Aromatics
  • Impurities