ChemicalBook > CAS DataBase List > D-(-)-3-Acetylthio-2-methylpropionic acid

D-(-)-3-Acetylthio-2-methylpropionic acid

Product Name
D-(-)-3-Acetylthio-2-methylpropionic acid
CAS No.
76497-39-7
Chemical Name
D-(-)-3-Acetylthio-2-methylpropionic acid
Synonyms
Captopril Impurity K;Captopril Impurity V;Captopril Impurity 7;Captopril EP Impurity G (S-Isomer);(2S)-3-(Acetylthio)-2-methylpropano;(S)-β-(Acetylmercapto)isobutyric acid;(S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID;(S)-β-(Acetylmercapto)isobutyric acid;D-(-)-3-Acetylthio-2-Methylpropionic A;Captopril Impurity G as (S)-enantiomer
CBNumber
CB4240644
Molecular Formula
C6H10O3S
Formula Weight
162.21
MOL File
76497-39-7.mol
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D-(-)-3-Acetylthio-2-methylpropionic acid Property

Melting point:
5 °C
Boiling point:
120-132 °C (1 mmHg)
alpha 
-46 º (c=1, 96% EtOH)
Density 
1.178 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.490
Flash point:
>230 °F
storage temp. 
Store at 0-5°C
solubility 
Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form 
liquid
pka
4.22±0.10(Predicted)
Water Solubility 
INSOLUBLE
CAS DataBase Reference
76497-39-7(CAS DataBase Reference)
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Safety

Hazard Codes 
C,T
Risk Statements 
34-36-24/25
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
HS Code 
29309070
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A1334
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Purity
>98.0%(T)
Packaging
5mL
Price
$74
Updated
2021/12/16
TCI Chemical
Product number
A1334
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Purity
>98.0%(T)
Packaging
25mL
Price
$220
Updated
2021/12/16
TRC
Product number
A188770
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
A188770
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Packaging
500mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0001116
Product name
(S)-(-)-3-ACETYLTHIO-2-METHYLPROPIONIC ACID
Purity
95.00%
Packaging
1G
Price
$120.75
Updated
2021/12/16
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D-(-)-3-Acetylthio-2-methylpropionic acid Chemical Properties,Usage,Production

Chemical Properties

clear colourless to slightly yellow liquid

Uses

ACE-inhibitors.

Uses

S-Acetylthio-2-methylpropionic acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.

D-(-)-3-Acetylthio-2-methylpropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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D-(-)-3-Acetylthio-2-methylpropionic acid Suppliers

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View Lastest Price from D-(-)-3-Acetylthio-2-methylpropionic acid manufacturers

Career Henan Chemical Co
Product
D-(-)-3-Acetylthio-2-methylpropionic acid 76497-39-7
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-15

76497-39-7, D-(-)-3-Acetylthio-2-methylpropionic acidRelated Search:

Butyl levulinate 3-Mercaptopropionic acid Citric acid Levulinic acid Folic acid Isobutyric acid 2,2-Bis(hydroxymethyl)propionic acid Acetyl chloride Glycine Methyl levulinate Ethyl 2-(Chlorosulfonyl)acetate Acetylacetone Ascoric Acid 2-Mercaptoethanol (R)-(+)-3-(ACETYLTHIO)-2-METHYLPROPIONIC ACID METHYL ESTER 3-ACETYLTHIO-2-METHYLPROPIONIC ACID,DL-BETA-ACETYLTHIO-ALPHA-METHYLPROPIONIC ACID,3-ACETYLTHIO-2-METHYLPROPANOIC ACID Propionic acid Captopril

  • D(-)S-ACETYL-BETA-MERCAPTO ISOBUTYRIC ACID
  • D-(S)-3-ACETYL-3-MERCAPTO-2-METHYL PROPANOIC ACID
  • D-(-)-3-ACETYLSULFANYL-2-METHYLPROPIONIC ACID
  • d-(-)-3-acetylthio-2-methylpropionic acid
  • (S)-β-(Acetylmercapto)isobutyric acid
  • D-3-(Acetylthio)-2-methylpropanoic acid
  • D-(S)-3-Acetylthio-2-methylpropionic acid
  • (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONI&
  • (-)-3-(Acetylthio)-2-methylpropanoic acid (Captopril Intermediate)
  • (S)-BETA-(ACETYLMERCAPTO)ISOBUTYRIC ACID
  • (S)-(-)-BETA-ACETYLTHIO-2-METHYLPROPIONIC ACID
  • (S)-(-)-3-(ACETYLMERCAPTO)ISOBUTYRIC ACID
  • (S)-(-)-3-ACETYLTHIO-2-METHYLPROPANOIC ACID
  • (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONIC ACID
  • (S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID
  • (S)-ACETYL-3-MERCAPTO-2-METHYLPROPANOIC ACID
  • (S)-(-)-ACETYLTHIO 2-METHYLPROPIONIC ACID
  • (S)-β-(Acetylmercapto)isobutyric acid, D-(-)-S-Acetyl-β-mercaptoisobutyric acid
  • Propanoic acid, 3-(acetylthio)-2-methyl-, (2S)-
  • (2S)-3-Acetylsulfanyl-2-methylpropanoate
  • (2S)-2-Methyl-3-(acetylthio)propionic acid
  • (S)-2-Methyl-3-(acetylthio)propionic acid
  • D(-)-S-Acetyl-beta-mercaptoisobutyric acid,99%
  • (S)-3-Acetylsulfanyl-2-Methylpropionic Acid
  • D-(-)-3-Acetylthio-2-Methylpropionic A
  • (2S)-3-(Acetylsulphanyl)-2-methylpropanoic acid, (2S)-3-(Acetylthio)-2-methylpropionic acid
  • Captopril Impurity K
  • Captopril EP Impurity G (S-Isomer)
  • (2S)-3-acetylthio-2-methylpropionic acid, D-(-)-S-3-acetylthio-2-methylpropanoic acid, (2S)-3-Acetylthio-2-methylpropanoic acid, (S)-3-(acetylthio)isobutyric acid, (S)-(-)-acetyl-β-mercaptoisobutyric acid, D-(-)-S-acetyl-β-mercaptoisobutyric acid, (S)-3-acetylsulfanyl-2-methyl-propionic acid
  • (S)-(-)-3-(Acetylthio)-2-methylpropionic acid≥ 99% ee (GC)
  • Captopril Impurity V
  • (2S)-3-acetylthio-2-methylpropionic acid
  • (2S)-3-(Acetylthio)-2-methylpropano
  • Captopril Impurity 7
  • (S)-β-(Acetylmercapto)isobutyric acid
  • Captopril Impurity G as (S)-enantiomer
  • Captopril EP Impurity G as (S)-enantiomer
  • 76497-39-7
  • 79497-39-7
  • C6H10O3S
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Organic Building Blocks
  • Thiocarbonyl Compounds
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry