6-CHLORO-1H-INDOLE-2-CARBALDEHYDE
- Product Name
- 6-CHLORO-1H-INDOLE-2-CARBALDEHYDE
- CAS No.
- 53590-59-3
- Chemical Name
- 6-CHLORO-1H-INDOLE-2-CARBALDEHYDE
- Synonyms
- 6-CHLORO-1H-INDOLE-2-CARBALDEHYDE;1H-Indole-2-carboxaldehyde, 6-chloro-
- CBNumber
- CB42455352
- Molecular Formula
- C9H6ClNO
- Formula Weight
- 179.6
- MOL File
- 53590-59-3.mol
6-CHLORO-1H-INDOLE-2-CARBALDEHYDE Property
- Boiling point:
- 373.4±22.0 °C(Predicted)
- Density
- 1.431±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 14.15±0.30(Predicted)
- Appearance
- Light yellow to brown Solid
Safety
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FC141350
- Product name
- 6-Chloro-1H-indole-2-carbaldehyde
- Packaging
- 100mg
- Price
- $84
- Updated
- 2021/12/16
- Product number
- JK271535
- Product name
- 6-Chloro-1H-indole-2-carbaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $138
- Updated
- 2021/12/16
- Product number
- FC141350
- Product name
- 6-Chloro-1H-indole-2-carbaldehyde
- Packaging
- 250mg
- Price
- $167.5
- Updated
- 2021/12/16
- Product number
- OR927744
- Product name
- 6-Chloro-1H-indole-2-carbaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $205
- Updated
- 2021/12/16
- Product number
- FC141350
- Product name
- 6-Chloro-1H-indole-2-carbaldehyde
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
6-CHLORO-1H-INDOLE-2-CARBALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Brown solid
Synthesis
53590-58-2
53590-59-3
GENERAL STEPS: A suspension of 2-hydroxymethyl-6-chloroindole (1 mmol) with activated MnO2 (10 mmol) in DMF (30 mL) was stirred at room temperature for 12 hours. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad. The filtrate was concentrated under vacuum and the residue was purified by column chromatography to afford 6-chloro-1H-indole-2-carbaldehyde using EtOAc-hexane mixed solvent as eluent.
References
[1] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 561 - 577
[2] Patent: US2003/144282, 2003, A1
[3] Journal of Medicinal Chemistry, 2007, vol. 50, # 6, p. 1380 - 1400
[4] Patent: US2008/9485, 2008, A1. Location in patent: Page/Page column 31
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 2, p. 364 - 377
6-CHLORO-1H-INDOLE-2-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
6-CHLORO-1H-INDOLE-2-CARBALDEHYDE Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58