6-Chloroindole-2-carboxylic acid ethyl ester

Product Name: 6-Chloroindole-2-carboxylic acid ethyl ester
CAS No.: 27034-51-1
Chemical Name: 6-Chloroindole-2-carboxylic acid ethyl ester
Synonyms: SPECS AP-283/40634148;6-CHLORO-2-INDOLECARBOXYLIC;Ethyl 6-chloroindole-2-carboxylate;Ethyl 6-Chloroindole-2-Carboxylicate;Ethyl 6-chloro-1H-indole-2-caboxylate;Ethyl6-chloroindole-2-carboxylate,97%;Ethyl 6-chloro-1H-indol-2-carboxylate;ETHYL 6-CHLORO-1H-INDOLE-2-CARBOXYLATE;6-CHLORO-2-INDOLECARBOXYLIC METHYL ESTER;6-Chlor-indol-2-carbonsaeure-aethylester
CBNumber: CB0342977
Molecular Formula: C11H10ClNO2
Formula Weight: 223.66
MOL File: 27034-51-1.mol

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6-Chloroindole-2-carboxylic acid ethyl ester Property

Melting point:: 169-171 °C
Boiling point:: 375.0±22.0 °C(Predicted)
Density: 1.329±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: Solid
pka: 14.11±0.30(Predicted)
Appearance: Light brown to gray Solid
CAS DataBase Reference: 27034-51-1(CAS DataBase Reference)

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: C380800
Product name: 6-Chloroindole-2-carboxylicacidethylester
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: C380800
Product name: 6-Chloroindole-2-carboxylicacidethylester
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 073585
Product name: Ethyl 6-chloroindole-2-carboxylate
Purity: 95+%
Packaging: 5g
Price: $68
Updated: 2021/12/16

Matrix Scientific

Product number: 073585
Product name: Ethyl 6-chloroindole-2-carboxylate
Purity: 95+%
Packaging: 1g
Price: $22
Updated: 2021/12/16

Matrix Scientific

Product number: 073585
Product name: Ethyl 6-chloroindole-2-carboxylate
Purity: 95+%
Packaging: 25g
Price: $240
Updated: 2021/12/16

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6-Chloroindole-2-carboxylic acid ethyl ester Chemical Properties,Usage,Production

Uses

Ethyl 6-chloroindole-2-carboxylate is an organic compound mainly used as a pharmaceutical intermediate and chemical reagent.

Synthesis

24513-05-1

27034-51-1

General method: 6a-d (9.2 mmol) was dissolved in toluene (150 mL) under nitrogen protection, rhodium(II) acetate dimer (203 mg, 0.46 mmol) was added, and the reaction was heated to reflux for 1-2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure, and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate, 25:1 to 18:1, v/v) to afford the target product ethyl 6-chloroindole-2-carboxylate (7a-d) in 51.7%-58.6% overall yields.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 6, p. 1760 - 1762
[2] Journal of Medicinal Chemistry, 1991, vol. 34, # 4, p. 1283 - 1292

6-Chloroindole-2-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Ethanol Diethyl oxalate Diethyl ether Hydrochloric acid Acetic acid Potassium 4-Chloro-2-nitrotoluene

Preparation Products

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6-Chloroindole-2-carboxylic acid ethyl ester Suppliers

China 113 Germany 3 India 4 The Netherlands 1 United Kingdom 7 United States 18 Global 146

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View Lastest Price from 6-Chloroindole-2-carboxylic acid ethyl ester manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-Chloroindole-2-carboxylic acid ethyl ester 27034-51-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 6-Chloroindole-2-carboxylic acid ethyl ester 27034-51-1
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1000KGS
Release date: 2020-01-14

27034-51-1, 6-Chloroindole-2-carboxylic acid ethyl esterRelated Search:

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SPECS AP-283/40634148

6-CHLOROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

6-Chloroindole-2-Carboxylic Acid Ethyl Acid

Ethyl 6-chloroindole-2-carboxylate

6-CHLORO-2-INDOLECARBOXYLIC METHYL ESTER

Ethyl 6-Chloroindole-2-Carboxylicate

6-CHLORO-2-INDOLECARBOXYLIC

6-Chloroindole-2-carboxylic acid ethyl ester ,99%

1H-Indole-2-carboxylic acid, 6-chloro-, ethyl ester

6-Chloro-1H-indole-2-carboxylic acid ethyl ester

Ethyl 6-chloro-1H-indole-2-caboxylate

6-Chlor-indol-2-carbonsaeure-aethylester

6-chlorindole-2-carboxylic acid ethyl ester

Ethyl6-chloroindole-2-carboxylate,97%

1H-Indole-2-carboxylic acid, 6-chloro-, ethyl ester (9CI, ACI)

6-chloro-1H-Indole-2-carboxylic acid ethyl ester (9CI ACI)

6-Chloroindole-2-carboxylic acid ethyl ester?New

ETHYL 6-CHLORO-1H-INDOLE-2-CARBOXYLATE

Ethyl 6-chloro-1H-indol-2-carboxylate

27034-51-1

C11H10ClNO2

Indole/indoline/oxindole

Indole and Indoline

Indole

Indoles