6-Chloroindole-2-carboxylic acid ethyl ester
- Product Name
- 6-Chloroindole-2-carboxylic acid ethyl ester
- CAS No.
- 27034-51-1
- Chemical Name
- 6-Chloroindole-2-carboxylic acid ethyl ester
- Synonyms
- SPECS AP-283/40634148;6-CHLORO-2-INDOLECARBOXYLIC;Ethyl 6-chloroindole-2-carboxylate;Ethyl 6-Chloroindole-2-Carboxylicate;Ethyl 6-chloro-1H-indole-2-caboxylate;Ethyl6-chloroindole-2-carboxylate,97%;Ethyl 6-chloro-1H-indol-2-carboxylate;ETHYL 6-CHLORO-1H-INDOLE-2-CARBOXYLATE;6-CHLORO-2-INDOLECARBOXYLIC METHYL ESTER;6-Chlor-indol-2-carbonsaeure-aethylester
- CBNumber
- CB0342977
- Molecular Formula
- C11H10ClNO2
- Formula Weight
- 223.66
- MOL File
- 27034-51-1.mol
6-Chloroindole-2-carboxylic acid ethyl ester Property
- Melting point:
- 169-171 °C
- Boiling point:
- 375.0±22.0 °C(Predicted)
- Density
- 1.329±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Solid
- pka
- 14.11±0.30(Predicted)
- Appearance
- Light brown to gray Solid
- CAS DataBase Reference
- 27034-51-1(CAS DataBase Reference)
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C380800
- Product name
- 6-Chloroindole-2-carboxylicacidethylester
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- C380800
- Product name
- 6-Chloroindole-2-carboxylicacidethylester
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 073585
- Product name
- Ethyl 6-chloroindole-2-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $68
- Updated
- 2021/12/16
- Product number
- 073585
- Product name
- Ethyl 6-chloroindole-2-carboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- 073585
- Product name
- Ethyl 6-chloroindole-2-carboxylate
- Purity
- 95+%
- Packaging
- 25g
- Price
- $240
- Updated
- 2021/12/16
6-Chloroindole-2-carboxylic acid ethyl ester Chemical Properties,Usage,Production
Uses
Ethyl 6-chloroindole-2-carboxylate is an organic compound mainly used as a pharmaceutical intermediate and chemical reagent.
Synthesis
24513-05-1
27034-51-1
General method: 6a-d (9.2 mmol) was dissolved in toluene (150 mL) under nitrogen protection, rhodium(II) acetate dimer (203 mg, 0.46 mmol) was added, and the reaction was heated to reflux for 1-2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure, and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate, 25:1 to 18:1, v/v) to afford the target product ethyl 6-chloroindole-2-carboxylate (7a-d) in 51.7%-58.6% overall yields.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 6, p. 1760 - 1762
[2] Journal of Medicinal Chemistry, 1991, vol. 34, # 4, p. 1283 - 1292
6-Chloroindole-2-carboxylic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
6-Chloroindole-2-carboxylic acid ethyl ester Suppliers
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View Lastest Price from 6-Chloroindole-2-carboxylic acid ethyl ester manufacturers
- Product
- 6-Chloroindole-2-carboxylic acid ethyl ester 27034-51-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 6-Chloroindole-2-carboxylic acid ethyl ester 27034-51-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2020-01-14