N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

Product Name: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester
CAS No.: 155405-81-5
Chemical Name: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester
Synonyms: Pemetrexed methyl ester;PeMetrexed DiMethyl Ester;Pemetrexed Impurity 21(Pemetrexed Dimethyl Ester);(E)-4-(4-((2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)imino)butyl)benzoic acid;4-[2-(2-Amino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-yl)ethyl]benzoic acid diethyl ester sulfonate;imethyl(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid dimethyl ester;1,5-dimethyl (2S)-2-{[4-(2-{2-amino-4-oxo-1H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate;N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester
CBNumber: CB42510112
Molecular Formula: C22H25N5O6
Formula Weight: 455.46
MOL File: 155405-81-5.mol

More

Less

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Property

Melting point:: >85°C (Subl.)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Dimethylformamide, DMSO, Methanol
pka: 13.01±0.46(Predicted)
form: Solid
color: Green
Major Application: pharmaceutical small molecule

More

Less

Safety

WGK Germany: WGK 3
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Muta. 2
Repr. 1A
Skin Irrit. 2
STOT RE 1

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H341Suspected of causing genetic defects

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P219525
Product name: PemetrexedMethylEster
Packaging: 1mg
Price: $110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0011381
Product name: PEMETREXED METHYL ESTER
Purity: 95.00%
Packaging: 1MG
Price: $349.65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0011381
Product name: PEMETREXED METHYL ESTER
Purity: 95.00%
Packaging: 5MG
Price: $499.7
Updated: 2021/12/16

More

Less

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

Protected Pemetrexed.

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Suppliers

Canada 1 China 46 India 5 United States 5 Global 57

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Quality Control Solutions Ltd.

Tel: 66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18390
Advantage: 56

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 0086-15250997978
Fax: 025-58362220
Email: sale@njxizebio.com
Country: China
ProdList: 4862
Advantage: 55

Tonichem Pharmaceutical Technology Co., Ltd.

Tel: +86 (0752) 222-7171, +86 15815821171
Fax: +86 (0752) 222-6171
Country: China
ProdList: 1120
Advantage: 58

Roark Standards

Tel: 0755-83552066 15986688328
Fax: 0755-83552066
Email: service@roarkstandards.com
Country: China
ProdList: 1442
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

155405-81-5, N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl esterRelated Search:

Pemetrexed Impurity 19 LY 338979 DiMethyl Ester Benzoic acid, 4-(1-methyl-3-oxopropyl)-, methyl ester (9CI) PeMetrexed IMpurity D N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid 3-Butyn-1-ol N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester Methyl 4-(4-oxobutyl)benzoate P219490 PeMetrexed EP IMpurity A Methyl 4-(4-hydroxybut-1-ynyl)benzoate 3-Buten-1-ol Pemetrexed Impurity 18 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester Pemetrexed Disodium 2,4-Diamino-6-hydroxypyrimidine

4-[2-(2-AMino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyriMidine-5-yl)ethyl]-L-GlutaMicAcidDiethylEsterP-TluensulfonicAcidsalt

Pemetrexed methyl ester

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

PeMetrexed DiMethyl Ester

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid dimethyl ester

Pemetrexed Impurity 21(Pemetrexed Dimethyl Ester)

dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

(E)-4-(4-((2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)imino)butyl)benzoic acid

L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, 1,5-dimethyl ester

1,5-dimethyl (2S)-2-{[4-(2-{2-amino-4-oxo-1H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate

imethyl(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

4-[2-(2-Amino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-yl)ethyl]benzoic acid diethyl ester sulfonate

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester USP/EP/BP

155405-81-5

Intermediates & Fine Chemicals

Pharmaceuticals