ChemicalBook > CAS DataBase List > Mal-PEG2-COOH

Mal-PEG2-COOH

Product Name
Mal-PEG2-COOH
CAS No.
756525-98-1
Chemical Name
Mal-PEG2-COOH
Synonyms
Mal-NH-PEG2-CH2CH2COOH;Mal-PEG2-COOH;MAL-dPEG2-acid;BMPA-PEG2-Acid;MAL-dPEG??-acid;Mal-NH-PEG2-COOH;MAL-AMIDO-PEG2-COOH;Mal-amido-PEG2-acid;Mal-amido-PEG2-C2-acid;Mal-amido-PEG2-NHS ester
CBNumber
CB42603836
Molecular Formula
C14H20N2O7
Formula Weight
328.32
MOL File
756525-98-1.mol
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Mal-PEG2-COOH Property

Boiling point:
617.3±55.0 °C(Predicted)
Density 
1.318±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, stored under nitrogen
solubility 
Soluble in DMSO
pka
4.28±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1472
Product name
Mal-amido-PEG2-acid
Packaging
250mg
Price
$131
Updated
2021/12/16
BroadPharm
Product number
BP-22212
Product name
Mal-amido-PEG2-acid
Purity
97%
Packaging
100mg
Price
$160
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG1555
Product name
mal-PEG(2)-COOH
Packaging
100mg
Price
$202.5
Updated
2021/12/16
Apolloscientific
Product number
BIPG1472
Product name
Mal-amido-PEG2-acid
Packaging
500mg
Price
$232
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG1555
Product name
mal-PEG(2)-COOH
Packaging
1g
Price
$270
Updated
2021/12/16
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Mal-PEG2-COOH Chemical Properties,Usage,Production

Description

Mal-amido-PEG2-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG2-COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG2-COOH Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from Mal-PEG2-COOH manufacturers

LAURENT
Product
Mal-NH-PEG2-CH2CH2COOH 756525-98-1
Price
US $321.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-17
Career Henan Chemica Co
Product
Mal-PEG2-COOH 756525-98-1
Price
US $3.37/g
Min. Order
1g
Purity
99%
Supply Ability
10kg,100kg
Release date
2020-11-06
Xian confluore Biological Technology Co., Ltd.
Product
Mal-amido-PEG2-acid 756525-98-1
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-27

756525-98-1, Mal-PEG2-COOHRelated Search:


  • Mal-PEG2-COOH
  • Mal-amido-PEG2-acid
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  • Maleimide-NH-PEG2-CH2CH2COOH
  • Maleimide-PEG2-propionic acid
  • MAL-AMIDO-PEG2-COOH
  • Mal-NH-PEG2-COOH
  • Mal-NH-PEG2-CH2CH2COOH
  • Mal-amido-PEG2-NHS ester
  • Mal-amido-PEG2-C2-acid
  • Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-
  • Mal-amido-PEG2-propionic acid
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  • MAL-dPEG2-acid
  • Mal-CH2CH2CONH-PEG2-CH2CH2COOH
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  • 3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoic acid
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  • 3-[2-[2-[3-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)propanamido]ethoxy]ethoxy]propionic Acid
  • 756525-98-1
  • 756525-97-1
  • Heterobifunctional PEG
  • peg