ChemicalBook > CAS DataBase List > (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one

(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one

Product Name
(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
CAS No.
327623-36-9
Chemical Name
(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
Synonyms
Arepitam Impurity 7;2S3S-R Fosaprepitant;Argatroban 4-Phenylmethyl;(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one;(2S,2αR)-4-benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]]ethoxy-morpholin-3-one;(2S,2αR)-4-benzyl-2-[1-[3,5-bis(trifluoroMethyl)phenyl]]ethoxy-Morpholin-3-one;(2S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone;3-Morpholinone, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-, (2S)-;(S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one (Aprepitant Impurity)
CBNumber
CB42657228
Molecular Formula
C21H19F6NO3
Formula Weight
447.37
MOL File
327623-36-9.mol
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(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Property

Boiling point:
457.4±45.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
pka
-2.18±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Chemical Properties,Usage,Production

Uses

Argatroban 4-Phenylmethyl is an impurity of Argatroban(A769000). Argatroban is a synthetic thrombin inhibitor and antithrombotic.

(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Suppliers

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327623-36-9, (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-oneRelated Search:

Aprepitant (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Aprepitant Impurity 6 Fosaprepitant Impurity 14 Aprepitant Aprepitant Fosaprepitant Impurity 6 (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Aprepitant Fosaprepitant Impurity 5 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one 1,1,1-Trimethoxy-2-chloroethane Aprepitant (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Benzyl dihydrogen phosphate

  • (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
  • (2S,2αR)-4-benzyl-2-[1-[3,5-bis(trifluoroMethyl)phenyl]]ethoxy-Morpholin-3-one
  • (2S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone
  • Arepitam Impurity 7
  • 2S3S-R Fosaprepitant
  • 3-Morpholinone, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-, (2S)-
  • Argatroban 4-Phenylmethyl
  • (S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one (Aprepitant Impurity)
  • (2S,2αR)-4-benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]]ethoxy-morpholin-3-one
  • 327623-36-9