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Ethyl 4-hydroxypiperidine-1-carboxylate

Product Name
Ethyl 4-hydroxypiperidine-1-carboxylate
CAS No.
65214-82-6
Chemical Name
Ethyl 4-hydroxypiperidine-1-carboxylate
Synonyms
N-CARBETHOXY-4-PIPERIDINOL;ETHYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE;N-Carbethoxy-4-piperidino;1-CARBETHOXY-4-PIPERIDINOL;N-Carboethoxypiperidine-4-Ol;Ethyl 4-Hydroxy-1-piperidine;Ethyl 4-hydroxypiperidine-1-;Ethyl 4-hydroxypiperidine-1-ca;1-ETHOXYCARBONYL-4-PIPERIDINOL;1-(Ethoxycarbonyl)piperidin-4-ol
CBNumber
CB4270153
Molecular Formula
C8H15NO3
Formula Weight
173.21
MOL File
65214-82-6.mol
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Ethyl 4-hydroxypiperidine-1-carboxylate Property

Boiling point:
120-130 °C(Press: 0.098 Torr)
Density 
1.12
refractive index 
1.4802
storage temp. 
Inert atmosphere,Room Temperature
form 
clear liquid
pka
14.80±0.20(Predicted)
color 
Colorless to Light yellow to Light orange
InChI
InChI=1S/C8H15NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h7,10H,2-6H2,1H3
InChIKey
QABJNOSERNVHDY-UHFFFAOYSA-N
SMILES
N1(C(OCC)=O)CCC(O)CC1
CAS DataBase Reference
65214-82-6(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E0656
Product name
Ethyl 4-Hydroxy-1-piperidinecarboxylate
Purity
>98.0%(GC)
Packaging
5g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
E0656
Product name
Ethyl 4-Hydroxy-1-piperidinecarboxylate
Purity
>98.0%(GC)
Packaging
25g
Price
$91
Updated
2024/03/01
TRC
Product number
B433603
Product name
ethyl4-hydroxypiperidine-1-carboxylate
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
B433603
Product name
ethyl4-hydroxypiperidine-1-carboxylate
Packaging
100mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK320705
Product name
Ethyl 4-Hydroxy-1-piperidinecarboxylate
Purity
99%
Packaging
5g
Price
$46
Updated
2021/12/16
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Ethyl 4-hydroxypiperidine-1-carboxylate Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

Ethyl 4-hydroxypethidine-1-carboxylate is mainly used as a pharmaceutical intermediate and a raw material for organic matter. It can be used in the synthesis of antihistamines, antipsychotics, antidepressants, and various pesticides. As an intermediate, the compound can also produce fungicides and insecticides. It can be used as a raw material for synthetic surfactants, flavors, and fragrances.

Preparation

Add triethylamine (1.5 equivalent) and ethyl chlorine 4-hydroxypiperidine-1-carboxylate (1.2 equivalent) to the dichloromethane solution of 4-hydroxypiperidine (1.0 equivalent) at 0 °C. Stir the mixture at 0 °C for 30 min. The reaction mixture is then poured into water and extracted with methylene chloride. Wash organic extracts with water and salt water. The compound is placed on sodium sulfate to dry. Finally, the organic extract is concentrated under reduced pressure to obtainEthyl 4-hydroxypiperidine-1-carboxylate.

Ethyl 4-hydroxypiperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4-hydroxypiperidine-1-carboxylate Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
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View Lastest Price from Ethyl 4-hydroxypiperidine-1-carboxylate manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Ethyl 4-hydroxypiperidine-1-carboxylate 65214-82-6
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-05-13
Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl 4-hydroxypiperidine-1-carboxylate 65214-82-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-10-24
Anhui Zhongda Biotechnology Co., Ltd
Product
Ethyl 4-hydroxypiperidine-1-carboxylate 65214-82-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100tons
Release date
2023-10-24

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