PHACLOFEN

Product Name: PHACLOFEN
CAS No.: 114012-12-3
Chemical Name: PHACLOFEN
Synonyms: PHACLOFEN;PHACLOFEN GABA(B) RECEPTOR ANTA;3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;3-amino-2-(4-chlorophenyl)*propanephosphonic acid;(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-;Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-;Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci
CBNumber: CB4272748
Molecular Formula: C9H13ClNO3P
Formula Weight: 249.63
MOL File: 114012-12-3.mol

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PHACLOFEN Property

Melting point:: 249-252 °C
Boiling point:: 467.1±55.0 °C(Predicted)
Density: 1.432±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: 0.1 M HCl: 13.3 mg/mL
form: solid
pka: 1.87±0.10(Predicted)
color: white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P118
Product name: Phaclofen
Purity: solid
Packaging: 5mg
Price: $132.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: P118
Product name: Phaclofen
Purity: solid
Packaging: 25mg
Price: $833
Updated: 2024/03/01

Sigma-Aldrich

Product number: P118
Product name: Phaclofen
Purity: solid
Packaging: 100mg
Price: $2520
Updated: 2024/03/01

Usbiological

Product number: 256229
Product name: Phaclofen
Packaging: 10mg
Price: $389
Updated: 2021/12/16

ApexBio Technology

Product number: B6215
Product name: Phaclofen
Packaging: 10mg
Price: $218
Updated: 2021/12/16

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PHACLOFEN Chemical Properties,Usage,Production

Uses

Phaclofen is a selective GABAB?receptor antagonist.

General Description

Phaclofen is a phosphonic acid derivative of baclofen.

Biological Activity

Selective GABA B antagonist. Phosphono analog of GABA B agonist baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid ).

Biochem/physiol Actions

Phaclofen plays a vital role in identifying the physiological importance of central and peripheral bicuculline-insensitive receptors with which GABA and (?) baclofen interact. Phaclofen acts as a GABAB receptor antagonist. Phaclofen has an ability to reversibly block the late, bicuculline resistant, K+ dependent inhibitory postsynaptic potential (IPSP) logged in projection cells of the cat and rat dorsal lateral geniculate nucleus and in rat hippocampal CA1 pyramidal neurons.

PHACLOFEN Preparation Products And Raw materials

Raw materials

Preparation Products

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PHACLOFEN Suppliers

China 29 Europe 1 Germany 3 Japan 1 Switzerland 2 United Kingdom 4 United States 10 USA 1 Global 51

EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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Aladdin Scientific

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ApexBio Technology

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United States Biological

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Riedel-de Haen AG

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2A PharmaChem USA

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3B Scientific Corporation

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BIOMOL INTERNATIONAL, LP

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MP Biomedicals, Inc.

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114012-12-3, PHACLOFENRelated Search:

3-Aminopropylphosphonic acid PHACLOFEN P-CHLORO-BETA-METHYL-PHENETHYLAMINE HYDROCHLORIDE (2-phenylethyl)phosphonic acid

3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID

PHACLOFEN

(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID

3-amino-2-(4-chlorophenyl)*propanephosphonic acid

PHACLOFEN GABA(B) RECEPTOR ANTA

Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-

Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-

Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci

114012-12-3

C9H13CINO3P

C9H13ClNO3P

GABA/Glycine receptor