ChemicalBook > CAS DataBase List > 5-Chlorothiophene-2-sulfonyl chloride
5-Chlorothiophene-2-sulfonyl chloride
- Product Name
- 5-Chlorothiophene-2-sulfonyl chloride
- CAS No.
- 2766-74-7
- Chemical Name
- 5-Chlorothiophene-2-sulfonyl chloride
- Synonyms
- AKOS B019398;BUTTPARK 27\04-09;TIMTEC-BB SBB003378;ART-CHEM-BB B019398;5-chlorothiophene-2-sulfonyl;5-CHLOROTHIOPHENESULPHONYL CHLORIDE;5-CHLORO-2-THIENYLSULFONYL CHLORIDE;5-Chlorothiophen-2-sulfonyl chloride;5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE;5-CHLORO-2-THIOPHENESULFONYL CHLORIDE
- CBNumber
- CB4283960
- Molecular Formula
- C4H2Cl2O2S2
- Formula Weight
- 217.09
- MOL File
- 2766-74-7.mol
More
Less
5-Chlorothiophene-2-sulfonyl chloride Property
- Melting point:
- 25-28°C
- Boiling point:
- 112-117 °C (lit.)
- Density
- 1.623 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.586(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- form
- solid
- Specific Gravity
- 1.623
- color
- Colorless to Yellow to Orange
- Water Solubility
- Not miscible in water.
- Sensitive
- Moisture Sensitive
- BRN
- 130710
- InChIKey
- SORSTNOXGOXWAO-UHFFFAOYSA-N
- CAS DataBase Reference
- 2766-74-7(CAS DataBase Reference)
More
Less
Safety
- Hazard Codes
- C
- Risk Statements
- 34-29-14
- Safety Statements
- 26-27-36/37/39-45-28A-25
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 3
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29349990
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 544272
- Product name
- 5-Chlorothiophene-2-sulfonyl chloride
- Purity
- 96%
- Packaging
- 5g
- Price
- $17.16
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 544272
- Product name
- 5-Chlorothiophene-2-sulfonyl chloride
- Purity
- 96%
- Packaging
- 1g
- Price
- $25
- Updated
- 2023/06/20
TCI Chemical
- Product number
- C2343
- Product name
- 5-Chloro-2-thiophenesulfonyl Chloride
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $59
- Updated
- 2024/03/01
TCI Chemical
- Product number
- C2343
- Product name
- 5-Chloro-2-thiophenesulfonyl Chloride
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $236
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A11348
- Product name
- 5-Chlorothiophene-2-sulfonyl chloride, 97%
- Packaging
- 1g
- Price
- $39.65
- Updated
- 2024/03/01
More
Less
5-Chlorothiophene-2-sulfonyl chloride Chemical Properties,Usage,Production
Chemical Properties
5-Chlorothiophene-2-sulfonyl chloride is white to yellow crystalline low melting solid
Uses
5-Chloro-2-thiophenesulfonyl Chloride is a sulfonylthiophene derivative used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.
Uses
5-Chlorothiophene-2-sulfonyl chloride is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It is used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.
Synthesis Reference(s)
Tetrahedron, 21, p. 1333, 1965 DOI: 10.1016/S0040-4020(01)98293-6
General Description
5-Chlorothiophene-2-sulfonyl chloride can be prepared from 2-chlorothiophene by reacting with chlorosulfonic acid in the presence of phosphorus pentachloride.
5-Chlorothiophene-2-sulfonyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
5-Chlorothiophene-2-sulfonyl chloride Suppliers
- Tel
- --
- Fax
- --
- Country
- Germany
- ProdList
- 72
- Advantage
- 58
- Tel
- --
- Fax
- --
- es@alfa.com
- Country
- Germany
- ProdList
- 5123
- Advantage
- 58
- Tel
- --
- Fax
- --
- chemos@chemos.de
- Country
- Germany
- ProdList
- 6727
- Advantage
- 58
- Tel
- --
- Fax
- --
- minakem-leuna@minakem.com
- Country
- Germany
- ProdList
- 157
- Advantage
- 50
- Tel
- --
- Fax
- --
- chemtec-leuna@siigroup.com
- Country
- Germany
- ProdList
- 123
- Advantage
- 42
- Tel
- --
- Fax
- --
- synthon@synthon-chemicals.com
- Country
- Germany
- ProdList
- 2000
- Advantage
- 65
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
- --
- Fax
- --
- akos@akosgmbh.de
- Country
- Germany
- ProdList
- 6717
- Advantage
- 72
More
Less
View Lastest Price from 5-Chlorothiophene-2-sulfonyl chloride manufacturers
Career Henan Chemical Co
- Product
- 5-Chlorothiophene-2-sulfonyl chloride 2766-74-7
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customise
- Release date
- 2018-08-09
2766-74-7, 5-Chlorothiophene-2-sulfonyl chlorideRelated Search:
Ethanesulfonyl chloride
Chloromethanesulfonyl chloride
Benzenesulfonyl chloride
Mepiquat chloride
Calcium chloride
Ammonium chloride
Sulfuryl chloride
Benzyl chloride
Choline chloride
Tosyl chloride
4-Nitrobenzenesulfonyl chloride
Polyvinyl chloride
Sodium chloride
Methylene Chloride
3-BROMO-5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE,3-Bromo-5-chlorothiophene-2-sulfonyl chloride, 95+%
5-CHLORO-4-NITROTHIOPHENE-2-SULFONYL CHLORIDE
4-Bromo-5-chlorothiophene-2-sulfonyl chloride, 95+%,4-BROMO-5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE,3-BROMO-2-CHLOROTHIOPHENE-5-SULFONYL CHLORIDE
2,3-Dichlorothiophene-5-sulphonyl chloride