L-(+)-Isoleucinol

Product Name: L-(+)-Isoleucinol
CAS No.: 24629-25-2
Chemical Name: L-(+)-Isoleucinol
Synonyms: L-ISOLEUCINOL;2-amino-3-methylpentan-1-ol;H-ILE-OL;L-Ile-ol;H-L-ILE-OL;H-ISOLEUCINOL;L(+)-ISOLEUCINOL;L-Isoleucinol>(+)-L-ISOLEUCINOL;(S)-(+)-ISOLEUCINOL
CBNumber: CB4284679
Molecular Formula: C6H15NO
Formula Weight: 117.19
MOL File: 24629-25-2.mol

More

Less

L-(+)-Isoleucinol Property

Melting point:: 36-39 °C(lit.)
Boiling point:: 97 °C14 mm Hg(lit.)
alpha: 4.5 º (c=1.6, EtOH)
Density: 0.9490 (rough estimate)
refractive index: n20/D 1.4589(lit.)
Flash point:: 213 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 12.88±0.10(Predicted)
form: Viscous Liquid
color: White to light yellow
optical activity: [α]20/D +4.0°, c = 1.6 in ethanol
InChI: InChI=1S/C6H15NO/c1-3-5(2)6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t5-,6+/m0/s1
InChIKey: VTQHAQXFSHDMHT-NTSWFWBYSA-N
SMILES: C(O)[C@@H](N)[C@@H](C)CC
CAS DataBase Reference: 24629-25-2(CAS DataBase Reference)
NIST Chemistry Reference: (S)-(+)-Isoleucinol(24629-25-2)

More

Less

Safety

Hazard Codes: C,Xi,Xn
Risk Statements: 34-22-40
Safety Statements: 45-36/37/39-26-36-22-24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29221990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 190527
Product name: (S)-(+)-Isoleucinol
Purity: 97%
Packaging: 1g
Price: $28.95
Updated: 2025/07/31

Sigma-Aldrich

Product number: 190527
Product name: (S)-(+)-Isoleucinol
Purity: 97%
Packaging: 5g
Price: $145
Updated: 2023/06/20

TCI Chemical

Product number: I0462
Product name: L-Isoleucinol
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $102
Updated: 2025/07/31

TCI Chemical

Product number: I0462
Product name: L-Isoleucinol
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $235
Updated: 2025/07/31

TRC

Product number: A614678
Product name: 2-Amino-3-methylpentan-1-ol
Packaging: 100mg
Price: $60
Updated: 2021/12/16

More

Less

L-(+)-Isoleucinol Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystalline solid or

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

73-32-5

24629-25-2

The general procedure for the synthesis of L-isoleucinol from L-isoleucine is as follows: the synthesis of L-isoleucinol was carried out by reference to the literature method 61 with minor adjustments. Lithium aluminum hydride (7.2 g, 0.19 mol, 2.5 eq.) was suspended in anhydrous tetrahydrofuran (120 mL) under nitrogen protection with continuous stirring. Subsequently, L-isoleucine (10 g, 0.08 mol) was added in batches and the reaction suspension was heated to reflux for 20 hours. Upon completion of the reaction, it was cooled to room temperature, ethyl acetate was added slowly and the reaction mixture was carefully poured into concentrated sodium hydroxide solution. The organic layer was extracted with water and the organic phase was subsequently dried with sodium sulfate. Removal of the solvent under reduced pressure gave 4.5 g of L-isoleucinol as a yellow oil, which could be used in subsequent reactions without further purification. The product was characterized by 1H NMR (400 MHz, CDCl3) with the following chemical shifts: δ 0.75-0.90 (6H, m), 1.01-1.17 (1H, m), 1.22-1.36 (1H, m), 1.37-1.50 (1H, m), 2.48 (2H, br s), 2.50-2.65 (1H, m), 3.19 -3.29 (1H, m), 3.57 (1H, dd, J = 3.27,10.64Hz) ppm.

References

[1] Synthetic Communications, 1996, vol. 26, # 4, p. 703 - 706
[2] Russian Chemical Bulletin, 2008, vol. 57, # 9, p. 1981 - 1988
[3] Helvetica Chimica Acta, 2004, vol. 87, # 1, p. 90 - 105
[4] Journal of Organic Chemistry, 1993, vol. 58, # 13, p. 3568 - 3571
[5] Chemical Communications, 1997, # 12, p. 1087 - 1088

L-(+)-Isoleucinol Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

L-(+)-Isoleucinol Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 191 Europe 3 France 1 Germany 8 India 9 Italy 1 Japan 5 Russia 1 Slovakia 1 South Korea 1 Switzerland 5 The Netherlands 1 United Kingdom 10 United States 44 Global 285

TCI Chemicals (India) Pvt. Ltd.

Tel: --
Fax: --
Email: sales-in@tcichemicals.com
Country: India
ProdList: 6768
Advantage: 58

Bharavi Laboratories (P) Ltd.

Tel: --
Fax: --
Email: bharavi@vsnl.com
Country: India
ProdList: 121
Advantage: 50

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: India
ProdList: 6905
Advantage: 58

Bharavi Laboratories (P) Limited

Tel: --
Fax: --
Country: India
ProdList: 67
Advantage: 58

Advent Chembio Pvt., Ltd.

Tel: --
Fax: --
Email: sales@adventchembio.com
Country: India
ProdList: 623
Advantage: 58

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

OCEAN TRADING CORPORATION

Tel: --
Fax: --
Email: otcchem@otcchem.com
Country: India
ProdList: 6202
Advantage: 58

Bharavi Laboratories (P) Ltd.

Tel: --
Fax: --
Email: bharavi@bgl.vsnl.net.in
Country: India
ProdList: 358
Advantage: 54

More

Less

View Lastest Price from L-(+)-Isoleucinol manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: L-isoleucinol 24629-25-2
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-05

Hebei Chuanghai Biotechnology Co., Ltd

Product: L-(+)-Isoleucinol 24629-25-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2025-03-07

Career Henan Chemical Co

Product: L-(+)-Isoleucinol 24629-25-2
Price: US $20.00/KG
Min. Order: 25KG
Purity: 99%
Supply Ability: 100kg
Release date: 2018-07-30

24629-25-2, L-(+)-IsoleucinolRelated Search:

(R)-TERT-LEUCINOL METHYLCYCLOPENTADIENE DIMER Ketorolac tromethamine Methyl acrylate Fosfomycin tromethamine Methyl acetate Kresoxim-methyl Lithium bis(trimethylsilyl)amide Dexketoprofen trometamol Mesityl oxide Methylparaben Methyl cyclopentenolone Bensulfuron methyl Thiophanate-methyl Hydrogenated Cottonseed Oil Tris(hydroxymethyl)aminomethane Methyl Parathion-methyl

(2S,3S)-2-AMINO-3-METHYL-PENTAN-1-OL

(2S,3S)-2-AMINO-3-METHYL-1-PENTANOL

2-AMINO-3-METHYL-1-PENTANOL

(S)-(+)-Isoleucinol,(2S,3S)-2-Amino-3-methyl-1-pentanol, L-Isoleucinol

(S)-(+)-Isoleucinol 97%

(S)-(-)-2-aMino-3-Methylpentan-1-ol

(S)-(+)-Isoleucinol, 95+%

L-Isoleucinol,99%e.e.

l-2-Amino-3-methyl-1-pentanol

[(2S,3S)-1-hydroxy-3-methylpentan-2-yl]ammonium

(+)-L-ISOLEUCINOL

L(+)-ISOLEUCINOL

L-ISOLEUCINOL

H-ILE-OL

H-L-ILE-OL

H-ISOLEUCINOL

(S)-(+)-2-AMINO-3-METHYL-1-PENTANOL

(S)-(+)-ISOLEUCINOL

(S,S)-2-AMINO-3-METHYL-1-PENTANOL

1-Pentanol, 2-amino-3-methyl-, [S-(R*,R*)]-

2-amino-3-methylpentan-1-ol

L-Ile-ol

(S)-(+)-ISOLEUCINOL / L-(+)-2-AMINO-3-METHYL-1-PENTANOL

1-PENTANOL, 2-AMINO-3-METHYL-, (2S,3S)-

(2S,3S)-2-Amino-3-methyl-1-pentanol, L-Isoleucinol

(2S,3S)-3-Methyl-2-amino-1-pentanol

L(+)-Isoleucinol,97%

L-Isoleucinol,(2S,3S)-2-Amino-3-methyl-1-pentanol

L-Isoleucinol&gt

L-(+)-Isoleucinol USP/EP/BP

(<i>S</i>)-(+)-Isoleucinol

24629-25-2

24629-25-1

C2H5CHCH3CHNH2CH2OH

Chiral Building Blocks

Amino Alcohols (Chiral)

Peptide Synthesis

Specialty Synthesis

Amino Alcohols

Amino Acid Derivatives

Pharmaceutical Intermediates

Amines

blocks

Amino Alcohols

Isoleucine [Ile, I]

Amino Alcohols (Chiral)

Chiral Building Blocks

Synthetic Organic Chemistry

Chiral Compound

Amino alcohols