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Sucrose octaacetate

Product Name
Sucrose octaacetate
CAS No.
126-14-7
Chemical Name
Sucrose octaacetate
Synonyms
Soa;FEMA 3038;SUCROSE OCTACETATE;Octa D;aacetate;204-772-1;bitter taste;OCTAACETYLSUCROSE;Sucrose octa actate;Sucrose octaacetate
CBNumber
CB4296191
Molecular Formula
C28H38O19
Formula Weight
678.59
MOL File
126-14-7.mol
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Sucrose octaacetate Property

Melting point:
82-85 °C(lit.)
Boiling point:
260 °C(lit.)
alpha 
D25.4 +58.5° (c = 2.56 in abs alcohol)
Density 
1.28
FEMA 
3038 | SUCROSE OCTAACETATE
refractive index 
60 ° (C=2, EtOH)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form 
Powder
color 
White to creamy white
Odor
odorless
Odor Type
odorless
optical activity
[α]22/D +58.8°, c = 2.5 in ethanol
Water Solubility 
SLIGHTLY SOLUBLE
Merck 
14,8881
BRN 
79290
InChIKey
ZIJKGAXBCRWEOL-SAXBRCJISA-N
LogP
3.19
CAS DataBase Reference
126-14-7(CAS DataBase Reference)
NIST Chemistry Reference
Sucrose, octaacetate(126-14-7)
EPA Substance Registry System
Sucrose octaacetate (126-14-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-37/39-26
WGK Germany 
2
RTECS 
WN6620000
F 
3
HS Code 
29400090
Toxicity
LD50 orally in Rabbit: 5000 mg/kg LD50 dermal Rabbit 5000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W303801
Product name
Sucrose octaacetate
Purity
≥97%, FG
Packaging
1 unit
Price
$53.48
Updated
2025/07/31
Sigma-Aldrich
Product number
W303801
Product name
Sucrose octaacetate
Purity
≥97%, FG
Packaging
1 unit
Price
$53.48
Updated
2025/07/31
Sigma-Aldrich
Product number
W303801
Product name
Sucrose octaacetate
Purity
≥97%, FG
Packaging
1kg
Price
$108
Updated
2025/07/31
Sigma-Aldrich
Product number
W303801
Product name
Sucrose octaacetate
Purity
≥97%, FG
Packaging
10Kg
Price
$687
Updated
2025/07/31
Sigma-Aldrich
Product number
W303801
Product name
Sucrose octaacetate
Purity
≥97%, FG
Packaging
25kg
Price
$1230
Updated
2025/07/31
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Sucrose octaacetate Chemical Properties,Usage,Production

Chemical Properties

white to creamy white powder

Chemical Properties

Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.

Chemical Properties

Sucrose octaacetate is odorless with an intensly bitter flavor influenced by food acids

Uses

LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide

Uses

Octa-O-acetyl D-(+)-Surcose was used in studies involving human bitter taste receptor hTAS2R46.

Uses

Adhesive; impregnating and insulating papers; in lacquers and plastics; as a denaturant for alcohol.

Definition

ChEBI: Sucrose octaacetate is a glycoside.

Preparation

May be prepared by heating sucrose, acetamide and sodium acetate; or by acetylation of sucrose using acetic anhydride, zinc chloride and acetic acid.

Production Methods

Sucrose octaacetate is typically produced by chemical synthesis; one reported synthetic method is by pyridine-catalyzed acetylation of sucrose.

Pharmaceutical Applications

Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.

Safety Profile

Slightly toxic by ingestion andskin contact. A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors.

Safety

Sucrose octaacetate is generally regarded as safe. It is considered slightly hazardous in cases of skin contact (irritant), ingestion, or inhalation.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg

storage

Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.

Purification Methods

After three recrystallisations from EtOH or 95% EtOH (charcoal), the m of the octaacetate rises to 88-90o, or Et2O with m 89o and [] D +58.5o (c 2.6, EtOH). It has a bitter taste. [Linstead et al. J Am Chem Soc 62 3260 1940, Lemieux & Huber J Am Chem Soc 78 4117 1956, Beilstein 17/8 V 410.]

Regulatory Status

GRAS listed. Approved by the FDA as both a direct and an indirect food additive, and as a nail-biting deterrent for over-the-counter drug products.

Sucrose octaacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sucrose octaacetate manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Sucrose octaacetate 126-14-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-11-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sucrose octaacetate 126-14-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
10000kgs
Release date
2021-10-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
Sucrose octaacetate 126-14-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-11

126-14-7, Sucrose octaacetateRelated Search:

Tocopherol Acetylsalicylic acid Sucrose fatty acid esters Ethylene glycol monoethyl ether acetate Dimethylbenzylcarbinyl acetate Ethylene glycol diacetate POLY(VINYL ACETATE) Sucrose Acetylspiramycin INDOPHENOL ACETATE Acetylcholine Acetaminophen Vinyl acetate Triacetin Sucralose Sucrose acetate isobutyrate Benzyl acetate SUCROSE MONOLAURATE

  • OCTA-O-ACETYL D-(+)-SACCHAROSE
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  • SUCROSEOCTAACETATE,NF
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  • [(2S,3S,4R,5R)-4-Acetyloxy-2,5-bis(acetyloxymethyl)-2-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyoxolan-3-yl] acetate
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  • Octa-O-acetylsucrose
  • 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-fructofuranosyl α-D-glucopyranoside 2,3,4,6-tetraacetate
  • 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-fructofuranosyl-α-D-glucopyranoside 2,3,4,6-tetraacetate
  • β-D-Fructofuranosyl α-D-glucopyranoside octaacetate
  • Sucrose octaacetate,98%
  • Sucrose octaacetate
  • Sucrose Octaacetate (500 mg)
  • D-(+)-Saccharose Octaacetate Octa-O-acetyl D-(+)-Saccharose D-(+)-Sucrose Octaacetate
  • Sucrose OCLaacetate
  • (2R,3R,4S,5R,6R)-2-(acetoxyMethyl)-6-(((2S,3S,4R,5R)-3,4-diacetoxy-2,5-bis(acetoxyMethyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate
  • Octa-O-acetyl D-(+)-Surcose
  • a-D-Glucopyranoside,1,3,4,6-tetra-O-acetyl-b-D-fructofuranosyl, 2,3,4,6-tetraacetate
  • D-(+)-Saccharose octaacetate for synthesis
  • Sucrose octaacetateOCTAACETATE
  • OCTAACETYLSUCROSE
  • SACCHAROSE OCTAACETATE
  • .alpha.-D-Glucopyranoside,1,3,4,6-tetra-O-acetyl-.beta.-D-fructofuranosyl,tetraacetate
  • 1,3,4,6-tetra-o-acetyl-beta-d-fructofuranosyl-alpha-d-glucopyranosidtetr
  • 1,3,4,6-Tetra-O-acetylhex-2-ulofuranosyl 2,3,4,6-tetra-O-acetylhexopyranoside
  • aacetate
  • alpha-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-beta-D-fructofuranosyl, tetraacetate
  • alpha-d-glucopyranoside,1,3,4,6-tetra-o-acetyl-beta-d-fructofuranosyl,tetra
  • Soa
  • FEMA 3038
  • D-(+)-SACCHAROSE OCTAACETATE
  • D-SACCHAROSE OCTAACETATE
  • D-(+)-SUCROSE OCTAACETATE
  • Octa-O-acetyl D-(+)-Sucrose &gt
  • Octa D
  • α-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-β-D-fructofuranosyl, 2,3,4,6-tetraacetate
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  • High Purity Best Price Sucrose Octaacetate CAS 126-14-7 with Best Price
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  • bitter taste
  • 2-PHENYLPROPIONALDEHYDE 93-53-8
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  • Sucrose octaacetate, 10 mM in DMSO
  • Bittering agent (Sucrose octaacetate)
  • <sc>D</sc>-(+)-Sucrose octaacetate
  • 126-14-7
  • 124-14-7
  • C28H38O19