Sucrose octaacetate
- Product Name
- Sucrose octaacetate
- CAS No.
- 126-14-7
- Chemical Name
- Sucrose octaacetate
- Synonyms
- Soa;FEMA 3038;SUCROSE OCTACETATE;Octa D;aacetate;204-772-1;bitter taste;OCTAACETYLSUCROSE;Sucrose octa actate;Sucrose octaacetate
- CBNumber
- CB4296191
- Molecular Formula
- C28H38O19
- Formula Weight
- 678.59
- MOL File
- 126-14-7.mol
Sucrose octaacetate Property
- Melting point:
- 82-85 °C(lit.)
- Boiling point:
- 260 °C(lit.)
- alpha
- D25.4 +58.5° (c = 2.56 in abs alcohol)
- Density
- 1.28
- FEMA
- 3038 | SUCROSE OCTAACETATE
- refractive index
- 60 ° (C=2, EtOH)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- form
- Powder
- color
- White to creamy white
- Odor
- odorless
- Odor Type
- odorless
- optical activity
- [α]22/D +58.8°, c = 2.5 in ethanol
- Water Solubility
- SLIGHTLY SOLUBLE
- Merck
- 14,8881
- BRN
- 79290
- InChIKey
- ZIJKGAXBCRWEOL-SAXBRCJISA-N
- LogP
- 3.19
- CAS DataBase Reference
- 126-14-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Sucrose, octaacetate(126-14-7)
- EPA Substance Registry System
- Sucrose octaacetate (126-14-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-37/39-26
- WGK Germany
- 2
- RTECS
- WN6620000
- F
- 3
- HS Code
- 29400090
- Toxicity
- LD50 orally in Rabbit: 5000 mg/kg LD50 dermal Rabbit 5000 mg/kg
N-Bromosuccinimide Price
- Product number
- W303801
- Product name
- Sucrose octaacetate
- Purity
- ≥97%, FG
- Packaging
- 1kg
- Price
- $105
- Updated
- 2024/03/01
- Product number
- W303801
- Product name
- Sucrose octaacetate
- Purity
- ≥97%, FG
- Packaging
- 10Kg
- Price
- $666
- Updated
- 2024/03/01
- Product number
- W303801
- Product name
- Sucrose octaacetate
- Purity
- ≥97%, FG
- Packaging
- 25kg
- Price
- $1200
- Updated
- 2024/03/01
- Product number
- 8.22144
- Product name
- D-(+)-Saccharose octaacetate
- Purity
- for synthesis
- Packaging
- 250g
- Price
- $67.5
- Updated
- 2024/03/01
- Product number
- 252603
- Product name
- D-(+)-Sucrose octaacetate
- Purity
- 98%
- Packaging
- 1kg
- Price
- $129
- Updated
- 2024/03/01
Sucrose octaacetate Chemical Properties,Usage,Production
Chemical Properties
white to creamy white powder
Chemical Properties
Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.
Chemical Properties
Sucrose octaacetate is odorless with an intensly bitter flavor influenced by food acids
Uses
LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide
Uses
Octa-O-acetyl D-(+)-Surcose was used in studies involving human bitter taste receptor hTAS2R46.
Uses
Adhesive; impregnating and insulating papers; in lacquers and plastics; as a denaturant for alcohol.
Definition
ChEBI: Sucrose octaacetate is a glycoside.
Preparation
May be prepared by heating sucrose, acetamide and sodium acetate; or by acetylation of sucrose using acetic anhydride, zinc chloride and acetic acid.
Production Methods
Sucrose octaacetate is typically produced by chemical synthesis; one reported synthetic method is by pyridine-catalyzed acetylation of sucrose.
Pharmaceutical Applications
Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.
Safety Profile
Slightly toxic by ingestion andskin contact. A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors.
Safety
Sucrose octaacetate is generally regarded as safe. It is considered
slightly hazardous in cases of skin contact (irritant), ingestion, or
inhalation.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg
storage
Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.
Purification Methods
After three recrystallisations from EtOH or 95% EtOH (charcoal), the m of the octaacetate rises to 88-90o, or Et2O with m 89o and [] D +58.5o (c 2.6, EtOH). It has a bitter taste. [Linstead et al. J Am Chem Soc 62 3260 1940, Lemieux & Huber J Am Chem Soc 78 4117 1956, Beilstein 17/8 V 410.]
Regulatory Status
GRAS listed. Approved by the FDA as both a direct and an indirect food additive, and as a nail-biting deterrent for over-the-counter drug products.
Sucrose octaacetate Preparation Products And Raw materials
Raw materials
Preparation Products
Sucrose octaacetate Suppliers
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- Country
- Germany
- ProdList
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View Lastest Price from Sucrose octaacetate manufacturers
- Product
- Sucrose Octaacetatee 126-14-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20MT
- Release date
- 2024-08-22
- Product
- Sucrose octaacetate 126-14-7
- Price
- US $99.00-66.00/kg
- Min. Order
- 0.001kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-09
- Product
- Octa-O-acetylsucrose 126-14-7
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-05-06