ChemicalBook > CAS DataBase List > Azido-PEG9-acid

Azido-PEG9-acid

Product Name: Azido-PEG9-acid
CAS No.: 1670249-37-2
Chemical Name: Azido-PEG9-acid
Synonyms: N3-PEG9-COOH;Azido-PEG9-acid;N3-PEG9-CH2CH2COOH;Azido-PEG9-CH2CH2COOH;1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid;N3-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-;3-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CBNumber: CB43062373
Molecular Formula: C21H41N3O11
Formula Weight: 511.57
MOL File: 1670249-37-2.mol

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Azido-PEG9-acid Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Safety

HS Code: 2929900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Apolloscientific

Product number: BIPG1110
Product name: Azido-PEG9-acid
Packaging: 50mg
Price: $166
Updated: 2021/12/16

ChemScene

Product number: CS-0108196
Product name: Azido-PEG9-acid
Packaging: 250mg
Price: $202
Updated: 2021/12/16

BroadPharm

Product number: BP-21825
Product name: Azido-PEG9-acid
Purity: 98%
Packaging: 100mg
Price: $230
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1110
Product name: Azido-PEG9-acid
Packaging: 100mg
Price: $283
Updated: 2021/12/16

BroadPharm

Product number: BP-21825
Product name: Azido-PEG9-acid
Purity: 98%
Packaging: 250mg
Price: $390
Updated: 2021/12/16

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Azido-PEG9-acid Chemical Properties,Usage,Production

Description

Azido-PEG9-acid is a PEG molecule consisting of an azide and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU).

Uses

Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Non-cleavable Linker

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG9-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azido-PEG9-acid manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid 1670249-37-2
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG9-Acid 1670249-37-2
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-23

1670249-37-2, Azido-PEG9-acidRelated Search:

N3-PEGn-OH 2K, 5K, 10K, 20K Azido-PEG11-alcohol Azido-PEG12-acid Azido-PEG10-acid Azido-PEG9-t-butyl ester Azido-PEG10-alcohol Polyethylene Glycol Azido-PEG10-azide N3-PEG9-CH2CH2NH2 Azido-PEG9-alcohol Azido-PEG9-NHS ester t-boc-N-amido-PEG9-azide Ethyl acetate N3-PEG10-N3 Azido-PEG9-Br Azido-PEG9-hydrazide N3-PEG9-Tos Hydrazoic acid

3-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Azido-PEG9-acid

N3-PEG9-CH2CH2COOH

N3-PEG9-COOH

N3-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-

Azido-PEG9-CH2CH2COOH

1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid

1670249-37-2

C21H41N3O11

peg