mPEG3-CH2COOH

ChemicalBook > CAS DataBase List > mPEG3-CH2COOH

Appearance

Product Name: mPEG3-CH2COOH
CAS No.: 16024-60-5
Chemical Name: mPEG3-CH2COOH
Synonyms: mPEG3-CH2COOH;m-PEG4-CH2COOH;mPEG3-acetic acid;MeO-(CH2CH2O)3-CH2COOH;3,6,9,12-Tetraoxatridecanoic acid;2,5,8,11-tetraoxatridecan-13-oic acid;2,5,8,11-Tetraoxa-13-tridecanoic Acid;mPEG3-CH2COOH/3,6,9,12-Tetraoxatridecanoic acid;2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid
CBNumber: CB43095676
Molecular Formula: C9H18O6
Formula Weight: 222.24
MOL File: 16024-60-5.mol

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mPEG3-CH2COOH Property

Boiling point:: 338.4±27.0 °C(Predicted)
Density: 1.127±0.06 g/cm3(Predicted)
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23432
Product name: m-PEG4-CH2COOH
Purity: 98%
Packaging: 1g
Price: $270
Updated: 2021/12/16

Activate Scientific

Product number: AS104070
Product name: mPEG3-CH2COOH
Purity: 95+%
Packaging: 1g
Price: $292
Updated: 2021/12/16

AK Scientific

Product number: 3727CR
Product name: 2,5,8,11-Tetraoxatridecan-13-oicacid
Packaging: 5g
Price: $836
Updated: 2021/12/16

Activate Scientific

Product number: AS104070
Product name: mPEG3-CH2COOH
Purity: 95+%
Packaging: 5G
Price: $874
Updated: 2021/12/16

Acrotein

Product number: B-0957
Product name: mPEG3-CH2COOH
Purity: 97%
Packaging: 0.5g
Price: $146.66
Updated: 2021/12/16

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mPEG3-CH2COOH Chemical Properties,Usage,Production

Appearance

White or Off-White Solid

Description

m-PEG4-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

3,6,9,12-Tetraoxatridecanoic acid is a useful research chemical.

Application

mPEG3-CH2COOH can be used to synthesise lipid couplers of oligo-(14-amino-3,6,9,12-tetraoxotetracosanoic acid) (ATTAn) as monodisperse analogues of poly(ethylene glycol) (PEG) derivatives for use in liposomal drug delivery systems^[1]. mPEG3-CH2COOH contains terminal carboxylic acids. The terminal carboxylic acid readily reacts with primary and secondary amines under EDC, DCC, HATU or other amide coupling conditions to form stable amide bonds. mPEG modification increases the water solubility of the resulting compounds.

References

[1] STEVEN M. ANSELL. Application of Oligo-(14-amino-3,6,9,12-tetraoxatetradecanoic acid) Lipid Conjugates as Steric Barrier Molecules in Liposomal Formulations[J]. Bioconjugate Chemistry Bioconjugate, 1999. DOI:10.1021/bc990005p.

mPEG3-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from mPEG3-CH2COOH manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 3,6,9,12-Tetraoxatridecanoic acid 16024-60-5
Price: US $30.00-2.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 30 tons
Release date: 2023-09-12

Hebei Guanlang Biotechnology Co., Ltd.

Product: 3,6,9,12-Tetraoxatridecanoic acid 16024-60-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-10-14

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: Methoxypoly(ethylene glycol) carboxymethyl 16024-60-5
Price: US $0.00-0.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100kg
Release date: 2021-06-01

16024-60-5, mPEG3-CH2COOHRelated Search:

Butyl acetate mPEG8-Alkyne MPEG3-CH2CH2COOH m-PEG5-bromide METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID m-PEG13-acid MPEG3-Propyne MPEG6-CH2CH2COOH MPEG7-CH2CH2COOH MPEG4-CH2CH2COOH 1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane m-PEG4-(CH2)3-acid m-PEG4-aldehyde Triethylene Glycol 2-Bromoethyl Methyl Ether 2,5,8,11,14-pentaoxahexadecan-16-oic acid [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid mPEG6-CH2COOH 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid

3,6,9,12-Tetraoxatridecanoic acid

2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid

m-PEG4-CH2COOH

2,5,8,11-tetraoxatridecan-13-oic acid

mPEG3-acetic acid

mPEG3-CH2COOH

2,5,8,11-Tetraoxa-13-tridecanoic Acid

MeO-(CH2CH2O)3-CH2COOH

mPEG3-CH2COOH/3,6,9,12-Tetraoxatridecanoic acid

16024-60-5