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ChemicalBook > CAS DataBase List > mPEG3-CH2COOH

mPEG3-CH2COOH

Appearance
Product Name
mPEG3-CH2COOH
CAS No.
16024-60-5
Chemical Name
mPEG3-CH2COOH
Synonyms
mPEG3-CH2COOH;m-PEG4-CH2COOH;mPEG3-acetic acid;MeO-(CH2CH2O)3-CH2COOH;3,6,9,12-Tetraoxatridecanoic acid;2,5,8,11-tetraoxatridecan-13-oic acid;2,5,8,11-Tetraoxa-13-tridecanoic Acid;mPEG3-CH2COOH/3,6,9,12-Tetraoxatridecanoic acid;2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid
CBNumber
CB43095676
Molecular Formula
C9H18O6
Formula Weight
222.24
MOL File
16024-60-5.mol
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mPEG3-CH2COOH Property

Boiling point:
338.4±27.0 °C(Predicted)
Density 
1.127±0.06 g/cm3(Predicted)
pka
3.39±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23432
Product name
m-PEG4-CH2COOH
Purity
98%
Packaging
1g
Price
$270
Updated
2021/12/16
Activate Scientific
Product number
AS104070
Product name
mPEG3-CH2COOH
Purity
95+%
Packaging
1g
Price
$292
Updated
2021/12/16
AK Scientific
Product number
3727CR
Product name
2,5,8,11-Tetraoxatridecan-13-oicacid
Packaging
5g
Price
$836
Updated
2021/12/16
Activate Scientific
Product number
AS104070
Product name
mPEG3-CH2COOH
Purity
95+%
Packaging
5G
Price
$874
Updated
2021/12/16
Acrotein
Product number
B-0957
Product name
mPEG3-CH2COOH
Purity
97%
Packaging
0.5g
Price
$146.66
Updated
2021/12/16
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mPEG3-CH2COOH Chemical Properties,Usage,Production

Appearance

White or Off-White Solid

Description

m-PEG4-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

3,6,9,12-Tetraoxatridecanoic acid is a useful research chemical.

Application

mPEG3-CH2COOH can be used to synthesise lipid couplers of oligo-(14-amino-3,6,9,12-tetraoxotetracosanoic acid) (ATTAn) as monodisperse analogues of poly(ethylene glycol) (PEG) derivatives for use in liposomal drug delivery systems[1]. mPEG3-CH2COOH contains terminal carboxylic acids. The terminal carboxylic acid readily reacts with primary and secondary amines under EDC, DCC, HATU or other amide coupling conditions to form stable amide bonds. mPEG modification increases the water solubility of the resulting compounds.

References

[1] STEVEN M. ANSELL. Application of Oligo-(14-amino-3,6,9,12-tetraoxatetradecanoic acid) Lipid Conjugates as Steric Barrier Molecules in Liposomal Formulations[J]. Bioconjugate Chemistry Bioconjugate, 1999. DOI:10.1021/bc990005p.

mPEG3-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from mPEG3-CH2COOH manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
3,6,9,12-Tetraoxatridecanoic acid 16024-60-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Hebei Yanxi Chemical Co., Ltd.
Product
3,6,9,12-Tetraoxatridecanoic acid 16024-60-5
Price
US $30.00-2.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
30 tons
Release date
2023-09-12
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Methoxypoly(ethylene glycol) carboxymethyl 16024-60-5
Price
US $0.00-0.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100kg
Release date
2021-06-01

16024-60-5, mPEG3-CH2COOHRelated Search:


  • 3,6,9,12-Tetraoxatridecanoic acid
  • 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid
  • m-PEG4-CH2COOH
  • 2,5,8,11-tetraoxatridecan-13-oic acid
  • mPEG3-acetic acid
  • mPEG3-CH2COOH
  • 2,5,8,11-Tetraoxa-13-tridecanoic Acid
  • MeO-(CH2CH2O)3-CH2COOH
  • mPEG3-CH2COOH/3,6,9,12-Tetraoxatridecanoic acid
  • 16024-60-5