ChemicalBook > CAS DataBase List > Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate

Product Name
Ethyl 2-chloronicotinate
CAS No.
1452-94-4
Chemical Name
Ethyl 2-chloronicotinate
Synonyms
AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;ETHYL 2-CHLORONICOTINATE;Ehtyl 2-chloronicotinate;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C;Ethyl2-chloronicotinate,98%
CBNumber
CB4312224
Molecular Formula
C8H8ClNO2
Formula Weight
185.61
MOL File
1452-94-4.mol
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Ethyl 2-chloronicotinate Property

Melting point:
68 C
Boiling point:
78°C (0.1 mmHg)
Density 
1.2445 g/cm3(Temp: 25 °C)
refractive index 
1.5210-1.5250
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-1.32±0.10(Predicted)
form 
Liquid
color 
Colorless to Light yellow to Light orange
InChI
InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3
InChIKey
PMIMPBYTPPRBGD-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=CC=C1C(OCC)=O
CAS DataBase Reference
1452-94-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-60-37
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000445
Product name
Flunixin impurity C
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000445
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2413
Product name
Flunixin Related Compound C
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50MG
Price
$534
Updated
2024/03/01
Sigma-Aldrich
Product number
1274631
Product name
Flunixin impurity C
Packaging
50mg
Price
$1720
Updated
2024/03/01
TCI Chemical
Product number
E0844
Product name
Ethyl 2-Chloronicotinate
Purity
>98.0%(GC)
Packaging
25g
Price
$44
Updated
2024/03/01
TCI Chemical
Product number
E0844
Product name
Ethyl 2-Chloronicotinate
Purity
>98.0%(GC)
Packaging
100g
Price
$130
Updated
2024/03/01
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Ethyl 2-chloronicotinate Chemical Properties,Usage,Production

Chemical Properties

Light yellow liquid

Uses

Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A

Synthesis

2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.

Ethyl 2-chloronicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 2-chloronicotinate Suppliers

Americas 1 Belgium 2 Canada 1 China 222 Europe 2 France 2 Germany 7 India 12 Italy 1 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 14 United States 46 Global 313
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View Lastest Price from Ethyl 2-chloronicotinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ethyl 2-chloronicotinate 1452-94-4
Price
US $0.00/KG
Min. Order
200KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-11
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Ethyl 2-chloronicotinate 1452-94-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-05
Shaanxi Dideu Medichem Co. Ltd
Product
Ethyl 2-chloronicotinate 1452-94-4
Price
US $4656.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-07-25

1452-94-4, Ethyl 2-chloronicotinateRelated Search:

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  • ETHYL 2-CHLORONICOTINATE
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  • 2-Chloropyridine-3-carboxylic acid ethyl ester
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  • Flunixin Related CoMpound C
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  • Ethyl2-chloronicotinate,98%
  • AVAC-001
  • oronicotinate
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  • Flunixin Meglumine EP Impurity C
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  • Ethyl 2-Chloropyridine-3-carboxylat
  • Flunixin EP Impurity C
  • Flunixin impurity CQ: What is Flunixin impurity C Q: What is the CAS Number of Flunixin impurity C Q: What is the storage condition of Flunixin impurity C Q: What are the applications of Flunixin impurity C
  • Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631)
  • Flunixin USP Related Compound C
  • ethy-2-chloroisonicoitate
  • Flunixin Meglumine Impurity C
  • Ehtyl 2-chloronicotinate
  • 1452-94-4
  • C8HBCINO2
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