4,4'-Methylenebis(N,N-dimethylaniline) Property

Melting point:

88-89 °C(lit.)

Boiling point:

390 °C

Density 

1.0344 (rough estimate)

refractive index 

1.5794 (estimate)

Flash point:

178 °C

storage temp. 

Sealed in dry,Room Temperature

form 

Crystalline Powder, Crystals and/or Chunks

pka

5.57±0.12(Predicted)

color 

Off-white or light gray or beige-brown

Water Solubility 

Insoluble

Merck 

14,6176

BRN 

479956

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, active metals, oxides, chlorates, halogenated compounds, iron chloride, nitro acompounds, peroxides, strong ammonia solution, sulfides, vinyl polymers.

InChIKey

JNRLEMMIVRBKJE-UHFFFAOYSA-N

CAS DataBase Reference

101-61-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 4,4'-methylenebis[N,N-dimethyl-(101-61-1)

IARC

2B (Vol. 27, Sup 7, 99) 2010

EPA Substance Registry System

4,4'-Methylenebis[N,N-dimethylaniline] (101-61-1)

Safety

Hazard Codes 

T,N,Xi

Risk Statements 

45-50/53

Safety Statements 

53-45-60-61

RIDADR 

UN 3077 9/PG 3

WGK Germany 

3

RTECS 

BY5250000

Hazard Note 

Harmful/Irritant

TSCA 

Yes

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29215990

Hazardous Substances Data

101-61-1(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H350May cause cancer

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

4,4'-Methylenebis(N,N-dimethylaniline) Chemical Properties,Usage,Production

Description

4,4-Methylenebis(N,N-dimethyl)benzenamineis a yellow crystalline compound. Molecular weight =254.41; Boiling point = 390℃; Freezing/Melting point =90- 91℃. Hazard Identification (based on NFPA-704 MRating System): Health 2, Flammability 1, Reactivity 0.Insoluble in water.

Chemical Properties

yellow to tan crystals

Chemical Properties

4,40 -Methylenebis(N,N-dimethyl)benzenamine is a yellow crystalline compound.

Uses

Has been used in manufacture of dyes. As reagent for lead: Dtsch. Med. Wochenschr. 52, 1855 (1926).

Uses

4,4'-Methylenebis(N,N-dimethylaniline)is used as a chemical intermediate in the manufacture of dyes and for its hydrochloric salt and is also used as an analytical reagent in the determination of lead.

Definition

ChEBI: 4,4'-Methylenebis(N,N-dimethylaniline) is a diarylmethane.

General Description

Yellowish glistening leaflets or plates or tan crystals. Weak odor. Sublimes without decomposition.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4,4'-Methylenebis(N,N-dimethylaniline) is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. 4,4'-Methylenebis(N,N-dimethylaniline) is also incompatible with active metals, potassium, oxides, chlorates, halogenated compounds, iron chloride, nitro compounds, peroxides, strong ammonia solutions, sulfides and vinyl polymers .

Fire Hazard

4,4'-Methylenebis(N,N-dimethylaniline) is combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx.

Potential Exposure

4,40 -methylenebis(N,N-dimethyl) benzenamine is used as an intermediate in dye manufacture and as an analytical reagent in the determination of lead.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobin in urine.

Carcinogenicity

4,4′-Methylenebis(N,N-dimethyl)benzenamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

storage

Color Code—Blue: Health Hazard/Poison: Store ina secure poison location. Prior to working with this chemicalyou should be trained on its proper handling and storage.4,40-Methylenebis(N,N-dimethyl)benzenamine must be storedto avoid contact with oxidizers (such as perchlorates, peroxides, permanganates, chlorates, and nitrates) and strong acids(such as hydrochloric, sulfuric, and nitric), since violent reactions occur. Store in tightly closed containers in a cool, wellventilated area. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045.

Shipping

UN3259 Amines, solid, corrosive, n.o.s, or Polyamines, solid, corrosive, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Crystallise the base from EtOH (2mL/g) or 95% EtOH (ca 12mL/g). It sublimes on heating. [Beilstein 13 IV 390.]

Incompatibilities

Strong acids, oxidizers, acid chlorides; acid anhydrides.