ChemicalBook > CAS DataBase List > 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

Product Name
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
CAS No.
109806-71-5
Chemical Name
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
Synonyms
Cetirizine -EP-Imp-G;Levocetirizine Impurity G;Levocetirizine Impurity 6;(R)-2-(4-((4-chlorophenyl);4-Chlorobisphenylmethylphenidate;2-[4-{Chlorophenyl}Phenylmethyl]-1-;Cetirizine EP Impurity G Hydrochloride;Levocetirizine Hydrochloride Impurity G;4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol;4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
CBNumber
CB4334224
Molecular Formula
C19H23ClN2O
Formula Weight
330.85
MOL File
109806-71-5.mol
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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Property

Boiling point:
205-208 °C(Press: 0.1 Torr)
Density 
1.191±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
14.96±0.10(Predicted)
color 
White to Off-White
Stability:
Very Hygroscopic
CAS DataBase Reference
109806-71-5(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C377565
Product name
4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
Packaging
250mg
Price
$205
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC53582
Product name
4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride
Packaging
5G
Price
$425
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC53582
Product name
4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride
Packaging
500mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC53582
Product name
4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride
Packaging
1g
Price
$110
Updated
2021/12/16
AK Scientific
Product number
1175BB
Product name
4-((4-Chlorophenyl)phenylmethyl)-1-piperazineethanol
Packaging
1g
Price
$131
Updated
2021/12/16
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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.

Uses

2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106).

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

4-Chlorobenzophenone Calcium chloride 2-Bromoethanol Toluene Sodium borohydride Triethylamine Piperazine 1,4-Dioxane Tetrahydrofuran Benzene Dichloromethane Isopropyl alcohol Thionyl chloride

Preparation Products

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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Suppliers

Canada 1 China 65 Europe 1 India 8 United Kingdom 5 United States 11 Global 91
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

109806-71-5, 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDERelated Search:

Levocetirizine Hydrochloride Impurity F Acetic acid, 2-[2-[2-[4-[(4- chlorophenyl)phenylMethyl]-1-piperazinyl]ethoxy]ethoxy]- Ethanol 4-[(4-chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride (intermediate of cetirizine dihydrochloride) Hydroxyzine-D8 Dihydrochloride Cetirizine (S)-Cetirizine Acetamide, 2-(2-(4-((2-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy )-, dihydrochloride Hydroxyzine dihydrochloride Levocetirizine 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

  • 2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL
  • 2-[4-{Chlorophenyl}Phenylmethyl]-1-
  • 2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol
  • Levocetirizine Impurity G
  • 4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone
  • 1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]-
  • (R)-2-(4-((4-chlorophenyl)
  • Levocetirizine Impurity 6
  • Cetirizine -EP-Imp-G
  • Cetirizine EP Impurity G Hydrochloride
  • 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
  • Cetirizine Impurity 15 Monomer （Cetirizine EP Impurity G Monomer ）
  • 4-Chlorobisphenylmethylphenidate
  • 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
  • Levocetirizine Hydrochloride Impurity G
  • 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethanol? (Cetirizine Impurity）
  • 4-(p-Chloro-alpha-phenylbenzyl)-1-piperazineethanol
  • 2-[4-([alpha]-phenyl-p-chloro-benzyl)piperazin-1-yl]ethanol
  • 4-(p-Chloro-a-phenylbenzyl)-1-piperazineethanol
  • 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORID
  • 109806-71-5
  • (intermediate of cetirizine dihydrochloride)