ChemicalBook > CAS DataBase List > 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

Product Name: 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
CAS No.: 109806-71-5
Chemical Name: 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
Synonyms: Cetirizine -EP-Imp-G;Levocetirizine Impurity G;Levocetirizine Impurity 6;(R)-2-(4-((4-chlorophenyl);4-Chlorobisphenylmethylphenidate;2-[4-{Chlorophenyl}Phenylmethyl]-1-;CETIRIZINE EP IMPURITY G (FREE BASE);Cetirizine EP Impurity G Hydrochloride;Levocetirizine Hydrochloride Impurity G;4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
CBNumber: CB4334224
Molecular Formula: C19H23ClN2O
Formula Weight: 330.85
MOL File: 109806-71-5.mol

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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Property

Boiling point:: 205-208 °C(Press: 0.1 Torr)
Density: 1.191±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: 14.96±0.10(Predicted)
color: White to Off-White
Stability:: Very Hygroscopic
InChI: InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2
InChIKey: ZJQSBXXYLQGZBR-UHFFFAOYSA-N
SMILES: N1(CCO)CCN(C(C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1
CAS DataBase Reference: 109806-71-5(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C377565
Product name: 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
Packaging: 250mg
Price: $205
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC53582
Product name: 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride
Packaging: 5G
Price: $425
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC53582
Product name: 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC53582
Product name: 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride
Packaging: 1g
Price: $110
Updated: 2021/12/16

AK Scientific

Product number: 1175BB
Product name: 4-((4-Chlorophenyl)phenylmethyl)-1-piperazineethanol
Packaging: 1g
Price: $131
Updated: 2021/12/16

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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.

Uses

2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106).

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

4-Chlorobenzophenone Calcium chloride 2-Bromoethanol Toluene Sodium borohydride Triethylamine Piperazine 1,4-Dioxane Tetrahydrofuran Benzene Dichloromethane Isopropyl alcohol Thionyl chloride

Preparation Products

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109806-71-5, 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDERelated Search:

Levocetirizine Hydrochloride Impurity F Acetic acid, 2-[2-[2-[4-[(4- chlorophenyl)phenylMethyl]-1-piperazinyl]ethoxy]ethoxy]- Ethanol 4-[(4-chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride (intermediate of cetirizine dihydrochloride) Hydroxyzine-D8 Dihydrochloride Cetirizine (S)-Cetirizine Acetamide, 2-(2-(4-((2-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy )-, dihydrochloride Hydroxyzine dihydrochloride Levocetirizine 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL

2-[4-{Chlorophenyl}Phenylmethyl]-1-

2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol

Levocetirizine Impurity G

4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone

1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]-

(R)-2-(4-((4-chlorophenyl)

Levocetirizine Impurity 6

Cetirizine -EP-Imp-G

Cetirizine EP Impurity G Hydrochloride

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol

Cetirizine Impurity 15 Monomer （Cetirizine EP Impurity G Monomer ）

4-Chlorobisphenylmethylphenidate

Levocetirizine Hydrochloride Impurity G

2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethanol? (Cetirizine Impurity）

4-(p-Chloro-alpha-phenylbenzyl)-1-piperazineethanol

2-[4-([alpha]-phenyl-p-chloro-benzyl)piperazin-1-yl]ethanol

4-(p-Chloro-a-phenylbenzyl)-1-piperazineethanol

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORID

CETIRIZINE EP IMPURITY G (FREE BASE)

Cetirizine EP Impurity G (Cetirizine USP Related Compound G (Free Form), Levocetirizine EP Impurity H)

109806-71-5

(intermediate of cetirizine dihydrochloride)