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2,6-Dimethylpyrazine

Description Reference
Product Name
2,6-Dimethylpyrazine
CAS No.
108-50-9
Chemical Name
2,6-Dimethylpyrazine
Synonyms
Pyrazine, 2,6-dimethyl-;2,6-Dimethylpiazine;FEMA 3273;FEMA NUMBER 3273;6-DiMethylpyrazine;3,5-Dimethylpyrazine;2,6-DIMETHYLPYRAZINE;2,6-dimethyl-pyrazin;2,6-SIMETHYLPYRAZINE;2.6-Dimethyl pryazine
CBNumber
CB4349060
Molecular Formula
C6H8N2
Formula Weight
108.14
MOL File
108-50-9.mol
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2,6-Dimethylpyrazine Property

Melting point:
35-40 °C(lit.)
Boiling point:
154 °C(lit.)
Density 
0.965(50.0000℃)
FEMA 
3273 | 2,6-DIMETHYLPYRAZINE
refractive index 
1.5000
Flash point:
127 °F
storage temp. 
-20°C
solubility 
Chloroform, Methanol (Slightly)
form 
Low Melting Crystalline Solid
pka
2.49±0.10(Predicted)
color 
Pale yellow
PH
7 (H2O, 20℃)
Odor
at 10.00 % in dipropylene glycol. ethereal cocoa nutty roasted roasted meaty beefy brown coffee buttermilk
Odor Type
chocolate
biological source
synthetic
Water Solubility 
Soluble in water.
JECFA Number
767
BRN 
1726
Dielectric constant
2.6499999999999999
LogP
0.64
CAS DataBase Reference
108-50-9(CAS DataBase Reference)
NIST Chemistry Reference
Pyrazine, 2,6-dimethyl-(108-50-9)
EPA Substance Registry System
Pyrazine, 2,6-dimethyl- (108-50-9)
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Safety

Hazard Codes 
Xn,F
Risk Statements 
10-22-37/38-41-11
Safety Statements 
16-26-39
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
3
RTECS 
UQ2975000
TSCA 
Yes
HazardClass 
4.1
PackingGroup 
III
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W327312
Product name
2,6-Dimethylpyrazine
Purity
natural (US)
Packaging
1 unit
Price
$153
Updated
2025/07/31
Sigma-Aldrich
Product number
W327312
Product name
2,6-Dimethylpyrazine
Purity
natural (US)
Packaging
1 unit
Price
$153
Updated
2025/07/31
Sigma-Aldrich
Product number
W327312
Product name
2,6-Dimethylpyrazine
Purity
natural (US)
Packaging
50g
Price
$576
Updated
2025/07/31
Sigma-Aldrich
Product number
W327312
Product name
2,6-Dimethylpyrazine
Purity
natural (US)
Packaging
250g
Price
$2300
Updated
2025/07/31
Sigma-Aldrich
Product number
W327301
Product name
2,6-Dimethylpyrazine
Purity
≥98%, FG
Packaging
1 unit
Price
$56.3
Updated
2025/07/31
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2,6-Dimethylpyrazine Chemical Properties,Usage,Production

Description

2,6-Dimethylpyrazine is one of alkylpyrazines. It occurs naturally in cocoa products, coffee, dairy products, meat, peanuts, pecans, filberts, potato products, rum and whisky, soy products. It is used as a flavoring agent in foods such as cereals and products such as cigarettes.

Reference

Glovanni Fenaroli, Fenaroli's Handbook of Flavor Ingredients, 1975, ISBN 0-87819-533-5

Chemical Properties

PALE YELLOW LOW MELTING CRYSTALLINE SOLID

Chemical Properties

2,6-Dimethylpyrazine has a nutty, coffee-like odor.

Occurrence

Reported found in cocoa products, coffee, diary products, peanuts, pecans, filberts, potato products, rum, whiskey, soy products, tomato puree, baked potato, cooked beef and chicken, mushroom, roasted barley, roasted pecan, tea, and Virginia tobacco; reported found in grilled beef; also a volatile flavor component of potato chips. Also reported found in cheeses, tamarind, coriander seed and corn tortilla

Uses

2,6-Dimethylpyrazine is used Preparation of chocolate, coffee, meat and nuts and other flavors

Definition

ChEBI: 2,6-Dimethylpyrazine is a member of pyrazines.

Preparation

By condensation of 1,2-diaminopropane, followed by column chromatography to separate the 2,6-methylpyrazine from the 2,5-dimethylpyrazine.

Aroma threshold values

Detection: 400 to 1500 ppb. Aroma characteristics at 1.0%: musty, cocoa powdery, tobacco, dry leaf tea, earthy mushroom cap and potato-like, meaty, roasted peanut shell, and coffee.

Taste threshold values

Taste characteristics at 5.0 ppm: musty and earthy, nutty peanut shell, cocoa powdery, earthy coffee, yeasty, woody, milk roasted peanut.

2,6-Dimethylpyrazine Preparation Products And Raw materials

Raw materials

2,5-Dimethyl pyrazine 1,2-Diaminopropane

Preparation Products

2,6-Dimethylpiperazine 3,5-DIMETHYL-2-ETHYLPYRAZINE
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2,6-Dimethylpyrazine Suppliers

Americas 2 Belgium 1 China 324 Europe 1 France 1 Germany 8 India 4 Japan 3 Norway 1 Singapore 1 Slovakia 1 Spain 2 Switzerland 2 The Netherlands 1 United Kingdom 19 United States 70 USA 1 Global 443
Pure Chemistry Scientific Inc.
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View Lastest Price from 2,6-Dimethylpyrazine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2,6-Dimethylpyrazine 108-50-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
2,6-Dimethylpyrazine 108-50-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-11
HebeiShuoshengImportandExportco.,Ltd
Product
2,6-Dimethylpyrazine 108-50-9
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08

108-50-9, 2,6-DimethylpyrazineRelated Search:

Glipizide Dimethyl ether ETHANE Dimethyl disulfide Dimethyl phthalate Dimethyl fumarate Dimethyl sulfate Dimethyl carbonate Dimethyl sulfoxide 2-Methylpyrazine N,N-Dimethylformamide Dacthal Pyrazinamide Sulfachoropyrazine sodium Pyrazine 2,3-Dimethylpyrazine,99%,2 3-DIMETHYLPYRAZINE 95+% FCC,dimethylpyrazine,2,3-dimethylpyrazine,2,3-dimethyl-1,4-diazine 2 5-DIMETHYLPYRAZINE FCC,dimethylpyrazine,2,5-dimethylpyrazine,2,5-dimethyl-1,4-diazine 2-AMINO-4-HYDROXYPTERIDINE-6-CARBOXYLIC ACID

  • 2,6-dimethyl-pyrazin
  • 2,6-dimethylpyrazine,balance2,5-isomer
  • 3,5-Dimethylpyrazine
  • FEMA NUMBER 3273
  • FEMA 3273
  • 2,6-DIMETHYLPYRAZINE
  • 2,6-DIMETHYL PARADIAZINE
  • 2,6-DIMETHYL-1,4-DIAZINE
  • 2 6-DIMETHYLPYRAZINE 98+% FCC
  • 2,6-Dimethylpiazine
  • dimethylpyrazine,2,6-dimethylpyrazine,2,6-dimethyl-1,4-diazine
  • Pyrazine, 2,6-dimethyl-
  • 2,6-DIMETHYLPYRAZINE, FEMA NO.3273
  • 2,6-SIMETHYLPYRAZINE
  • 1,2-Propanediol, 3-(ethylthio)-
  • 3-Ethylsulfanylpropane-1,2-diol
  • 2,6-Dimethylpyrazine ,98%
  • 2,6-DIMETHYLPYRAZINE, 96%, BALANCE 2,5-ISOMER
  • 6-DiMethylpyrazine
  • 2,6-DiMethylpyrazine, balance 2,5-isoMer, 96% 5GR
  • 2,6-DIMETHYLPYRAZINE FOR SYNTHESIS
  • 2,6-Dimethylpyrazine,typically96%
  • 2,6-Dimethylpyrazine, typically 96%
  • 2,6-Dimethylpyrazine &gt
  • 2,6-Dimethylpyrazine USP/EP/BP
  • 2,6-Dimethylpyrazine CAS 108-50-9 with good price
  • 2.6-Dimethyl pryazine
  • 108-50-9 2,6-Dimethylpyrazine
  • Posaconazole 171228-49-2
  • Glipizide Impurity 43
  • 2,6-Dimethylpyrazine in isooctane
  • 2,6-Dimethylpyrazine, 10 mM in DMSO
  • 108-50-9
  • Pyrazines
  • Mono- & Polyalkylpyrazines
  • Building Blocks
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Alphabetical Listings
  • C-D
  • Flavors and Fragrances
  • Mono- & Polyalkylpyrazines
  • pyrazine Flavor
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Pharmaceutical Raw Materials
  • Pyrazine
  • Heterocyclic Compounds
  • Pyrazines