Mezlocillin sodium

ChemicalBook > CAS DataBase List > Mezlocillin sodium

Product Name: Mezlocillin sodium
CAS No.: 59798-30-0
Chemical Name: Mezlocillin sodium
Synonyms: Chebi:52067;MEZLOCILLIN SODIUM;Mezlocillin　Baypen;Meloxicillin sodium;Sodium salt monohydrate;Mezlocillin (sodium salt);Mezlocillin Sodium (350 mg);Mezlocillin sodium USP/EP/BP;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanate;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate
CBNumber: CB4353793
Molecular Formula: C22H27N6NaO9S2
Formula Weight: 606.6
MOL File: 59798-30-0.mol

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Mezlocillin sodium Property

Melting point:: 197-201°C (dec.)
storage temp.: Refrigerator
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Water Solubility: Soluble in water or DMSO
CAS DataBase Reference: 59798-30-0(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J66306
Product name: Mezlocillin sodium salt
Packaging: 100mg
Price: $215
Updated: 2024/03/01

Alfa Aesar

Product number: J66306
Product name: Mezlocillin sodium salt
Packaging: 500mg
Price: $515
Updated: 2021/12/16

Cayman Chemical

Product number: 30691
Product name: Mezlocillin (sodium salt)
Packaging: 500mg
Price: $290
Updated: 2024/03/01

Cayman Chemical

Product number: 30691
Product name: Mezlocillin (sodium salt)
Packaging: 1g
Price: $547
Updated: 2024/03/01

Cayman Chemical

Product number: 30691
Product name: Mezlocillin (sodium salt)
Packaging: 250mg
Price: $153
Updated: 2024/03/01

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Mezlocillin sodium Chemical Properties,Usage,Production

Description

Mezlocillin is a β-lactam antibiotic and derivative of ampicillin . It is active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 μg/ml, respectively). Mezlocillin (32 μg/ml) is also active against 10 strains of S. faecalis. In vivo, mezlocillin (240 mg/kg) increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis. It completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection when administered at a dose of 300 mg/kg. Formulations containing mezlocillin have been used in the treatment of various bacterial infections.

Chemical Properties

Mezlocillin sodium is white to slightly yellow cryst. powder

Uses

Antibacterial.

Uses

Mezlocillin Sodium (cas# 59798-30-0) is a derivative of penicillin and an antimicrobial.

Definition

ChEBI: Mezlocillin sodium is an organic sodium salt. It contains a mezlocillin(1-).

brand name

Mezlin (Bayer).

Clinical Use

Mezlocillin (Mezlin) is an acylureidopenicillin with an antibacterialspectrum similar to that of carbenicillin andticarcillin; however, there are some major differences. It ismuch more active against most Klebsiella spp., P. aeruginosa,anaerobic bacteria (e.g., Streptococcus faecalis andB. fragilis), and H. influenzae. It is recommended for thetreatment of serious infections caused by these organisms.
Mezlocillin is not generally effective against β-lactamase–producing bacteria, nor is it active orally. It isavailable as a white, crystalline, water-soluble sodium saltfor injection. Solutions should be prepared freshly and, ifnot used within 24 hours, refrigerated. Mezlocillin and otheracylureidopenicillins, unlike carbenicillin, exhibit nonlinearpharmacokinetics. Peak plasma levels, half-life, and areaunder the time curve increase with increased dosage.Mezlocillin has less effect on bleeding time than carbenicillin,and it is less likely to cause hypokalemia.

Mezlocillin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mezlocillin sodium manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Mezlocillin Sodium 59798-30-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-21

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Mezlocillin Sodium 59798-30-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-04-29

Hebei Mojin Biotechnology Co., Ltd

Product: Mezlocillin sodium 59798-30-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-06-30

59798-30-0, Mezlocillin sodiumRelated Search:

Sodium benzoate Dimethyl sulfate Dimethyl carbonate ETHANE Sodium alginate Dimethyl ether Sodium acetate Sodium chloride Dacthal Diclofenac sodium Sodium bicarbonate Dimethyl sulfide Sodium hydroxide N,N-Dimethylformamide Dimethyl sulfoxide Dimethyl sebacate Dimethyl fumarate Acetaminophen

(2S,5R,6R)-3,3-DiMethyl-6-((R)-2-(3-(3-(Methylsulfonyl)-2-oxoiMidazolidine-1-carbonyl)ureido)-2-phenylacetaMido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, sodiuM salt

Chebi:52067

Sodium (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate

Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanate

Mezlocillin Sodium (350 mg)

sodium 3,3-dimethyl-6-[[2-[[(3-methylsulfonyl-2-oxo-1-imidazolidinyl)-oxomethyl]amino]-1-oxo-2-phenylethyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

3,3-dimethyl-6-[[2-[(3-methylsulfonyl-2-oxo-imidazolidin-1-yl)carbonylamino]-2-phenyl-acetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt

MEZLOCILLIN SODIUM

Sodium salt monohydrate

Mezlocillin　Baypen

Mezlocillin (sodium salt)

Mezlocillin sodium USP/EP/BP

Meloxicillin sodium

59798-30-0

C21H24N5NaO8S2

C21H24N5O8S2NaH2O

C21H24NaN5O8S2H2O

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