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Mezlocillin sodium

Product Name
Mezlocillin sodium
CAS No.
59798-30-0
Chemical Name
Mezlocillin sodium
Synonyms
Chebi:52067;MEZLOCILLIN SODIUM;Mezlocillin Baypen;Meloxicillin sodium;Sodium salt monohydrate;Mezlocillin (sodium salt);Mezlocillin Sodium (350 mg);Mezlocillin sodium USP/EP/BP;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanate;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate
CBNumber
CB4353793
Molecular Formula
C22H27N6NaO9S2
Formula Weight
606.6
MOL File
59798-30-0.mol
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Mezlocillin sodium Property

Melting point:
197-201°C (dec.)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
Soluble in water or DMSO
CAS DataBase Reference
59798-30-0(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66306
Product name
Mezlocillin sodium salt
Packaging
100mg
Price
$215
Updated
2024/03/01
Alfa Aesar
Product number
J66306
Product name
Mezlocillin sodium salt
Packaging
500mg
Price
$515
Updated
2021/12/16
Cayman Chemical
Product number
30691
Product name
Mezlocillin (sodium salt)
Packaging
500mg
Price
$290
Updated
2024/03/01
Cayman Chemical
Product number
30691
Product name
Mezlocillin (sodium salt)
Packaging
1g
Price
$547
Updated
2024/03/01
Cayman Chemical
Product number
30691
Product name
Mezlocillin (sodium salt)
Packaging
250mg
Price
$153
Updated
2024/03/01
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Mezlocillin sodium Chemical Properties,Usage,Production

Description

Mezlocillin is a β-lactam antibiotic and derivative of ampicillin . It is active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 μg/ml, respectively). Mezlocillin (32 μg/ml) is also active against 10 strains of S. faecalis. In vivo, mezlocillin (240 mg/kg) increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis. It completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection when administered at a dose of 300 mg/kg. Formulations containing mezlocillin have been used in the treatment of various bacterial infections.

Chemical Properties

Mezlocillin sodium is white to slightly yellow cryst. powder

Uses

Antibacterial.

Uses

Mezlocillin Sodium (cas# 59798-30-0) is a derivative of penicillin and an antimicrobial.

Definition

ChEBI: Mezlocillin sodium is an organic sodium salt. It contains a mezlocillin(1-).

brand name

Mezlin (Bayer).

Clinical Use

Mezlocillin (Mezlin) is an acylureidopenicillin with an antibacterialspectrum similar to that of carbenicillin andticarcillin; however, there are some major differences. It ismuch more active against most Klebsiella spp., P. aeruginosa,anaerobic bacteria (e.g., Streptococcus faecalis andB. fragilis), and H. influenzae. It is recommended for thetreatment of serious infections caused by these organisms.
Mezlocillin is not generally effective against β-lactamase–producing bacteria, nor is it active orally. It isavailable as a white, crystalline, water-soluble sodium saltfor injection. Solutions should be prepared freshly and, ifnot used within 24 hours, refrigerated. Mezlocillin and otheracylureidopenicillins, unlike carbenicillin, exhibit nonlinearpharmacokinetics. Peak plasma levels, half-life, and areaunder the time curve increase with increased dosage.Mezlocillin has less effect on bleeding time than carbenicillin,and it is less likely to cause hypokalemia.

Mezlocillin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Mezlocillin sodium Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Mezlocillin sodium manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Mezlocillin Sodium 59798-30-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Mezlocillin Sodium 59798-30-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-29
Hebei Mojin Biotechnology Co., Ltd
Product
Mezlocillin sodium 59798-30-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-30

59798-30-0, Mezlocillin sodiumRelated Search:


  • (2S,5R,6R)-3,3-DiMethyl-6-((R)-2-(3-(3-(Methylsulfonyl)-2-oxoiMidazolidine-1-carbonyl)ureido)-2-phenylacetaMido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, sodiuM salt
  • Chebi:52067
  • Sodium (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate
  • Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanate
  • Mezlocillin Sodium (350 mg)
  • sodium 3,3-dimethyl-6-[[2-[[(3-methylsulfonyl-2-oxo-1-imidazolidinyl)-oxomethyl]amino]-1-oxo-2-phenylethyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • 3,3-dimethyl-6-[[2-[(3-methylsulfonyl-2-oxo-imidazolidin-1-yl)carbonylamino]-2-phenyl-acetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
  • MEZLOCILLIN SODIUM
  • Sodium salt monohydrate
  • Mezlocillin Baypen
  • Mezlocillin (sodium salt)
  • Mezlocillin sodium USP/EP/BP
  • Meloxicillin sodium
  • 59798-30-0
  • C21H24N5NaO8S2
  • C21H24N5O8S2NaH2O
  • C21H24NaN5O8S2H2O
  • Miscellaneous