ChemicalBook > CAS DataBase List > 5'-DMT-RIBO ADENOSINE (N-BZ)

5'-DMT-RIBO ADENOSINE (N-BZ)

Product Name
5'-DMT-RIBO ADENOSINE (N-BZ)
CAS No.
81246-82-4
Chemical Name
5'-DMT-RIBO ADENOSINE (N-BZ)
Synonyms
DMT-rA(Bz);N6-Bz-DMT-Ar;5'-DMT-Bz-rA;5'-O-DMT-Bz-rA;5'-O-DMT-N6-Bz Adenosine;N6-Bz-5'-O-DMT-adenosine;-DMT-RIBO ADENOSINE (N-BZ);5’-O-DMTr-Adenosine (N-bz);5'-DMT-RIBO ADENOSINE (N-BZ);5'-O-DMTr-N6-benzoyladenosine
CBNumber
CB4391155
Molecular Formula
C38H35N5O7
Formula Weight
673.71
MOL File
81246-82-4.mol
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5'-DMT-RIBO ADENOSINE (N-BZ) Property

Density 
1.36
storage temp. 
Sealed in dry,2-8°C
form 
Solid
pka
7.87±0.43(Predicted)
color 
White to off-white
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D494208
Product name
5''-DMT-Bz-rA
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
NB07167
Product name
N6-Benzoyl-5'-O-DMT-adenosine
Packaging
1g
Price
$65
Updated
2021/12/16
Ark Pharm
Product number
P000083611
Product name
5'-DMT-Bz-rA
Purity
95+%
Packaging
10g
Price
$68
Updated
2021/12/16
Ark Pharm
Product number
P000083611
Product name
5'-DMT-Bz-rA
Purity
95+%
Packaging
250mg
Price
$8
Updated
2021/12/16
Ark Pharm
Product number
P000083611
Product name
5'-DMT-Bz-rA
Purity
95+%
Packaging
1g
Price
$10
Updated
2021/12/16
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5'-DMT-RIBO ADENOSINE (N-BZ) Chemical Properties,Usage,Production

Uses

5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds?synthesis[1].

Synthesis

40615-36-9

4546-55-8

129666-75-7

The general procedure for the synthesis of the target compound (CAS: 129666-75-7) from 4,4'-dimethoxytrityl chloride (DMTrCl) and N6-benzoyl adenosine was as follows: to a pyridine solution (100 g, 269.3 mmol, 0.5 mmol) containing N-(9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl) at 0 °C, N-(9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl )-benzamide (100 g, 269.3 mmol) to a pyridine solution (500 mL) was added DMAP (1.64 g, 13.46 mmol, 0.05 equiv) and DMTrCl (100.4 g, 296.2 mmol, 1.1 equiv) in sequence. The reaction mixture was stirred at room temperature for 16 h. Upon completion of the reaction, the reaction was quenched by addition of methanol (500 mL). Volatiles were removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography (elution gradient: 1/1 petroleum ether/ethyl acetate to 100% ethyl acetate) to afford N-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzene Formamide, as a white foamy solid (150 g, 223 mmol, 83% yield).

References

[1] Boyu Zhong, et al. Cyclic di-nucleotide compounds and methods of use. Patent WO2017161349.

5'-DMT-RIBO ADENOSINE (N-BZ) Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-DMT-RIBO ADENOSINE (N-BZ) Suppliers

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View Lastest Price from 5'-DMT-RIBO ADENOSINE (N-BZ) manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4
Price
US $0.00-0.00/G
Min. Order
1G
Purity
98%
Supply Ability
2000
Release date
2025-06-04
Henan Aochuang Chemical Co.,Ltd.
Product
5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29
Career Henan Chemical Co
Product
5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4?
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-21

81246-82-4, 5'-DMT-RIBO ADENOSINE (N-BZ)Related Search:

Diphenyldimethoxysilane 1,1-Dimethoxyethane 5'-Deoxyadenosylcobalamin Adenosine 2,6-Dimethoxybenzaldehyde ADENOSINE 5'-TRIPHOSPHATASE Benzoyl chloride Vidarabine Dimethyldimethoxysilane Benzoyl peroxide Dimethoxymethane N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-tert-butyldimethylsilyl guanosine 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine N-BENZOYLADENOSINE 5'-DMT-RIBO ADENOSINE (N-BZ)

  • N6-Benzoyl-5'-O-DMT-adenosine
  • DTN-006 5'-O-(4,4'-DiMethoxytrityl)-N6-benzoyl-adenosine
  • 5'-DMT-Bz-rA
  • 5'-O-DMT-N6-Bz Adenosine
  • N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine
  • N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]adenosine
  • N6-Bz-DMT-Ar
  • 5'-O-dimethoxytrityl-N6-benzoyl adenosine
  • N-[9-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]purin-6-yl]benzamide
  • Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-
  • 5'-O-DMTr-N6-benzoyladenosine
  • N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-ADENOSINE
  • 5'-DMT-RIBO ADENOSINE (N-BZ)
  • -DMT-RIBO ADENOSINE (N-BZ)
  • 5'-O-DMT-Bz-rA
  • 5'-DMT-RIBO ADENOSINE (N-BZ) USP/EP/BP
  • C38H35N5O7 5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4
  • 5'-O-DMT-N6-Benzoyl-Adenosine
  • N6-Bz-5'-O-DMT-adenosine
  • N-(9-((2S,3S,4R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
  • 6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine
  • N-(9-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
  • 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine
  • N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]purin-6-yl]benzamide
  • DMT-rA(Bz)
  • 5'-DMT-RIBOADENOSINChemicalbookE(N-BZ)
  • 5’-O-DMTr-Adenosine (N-bz)
  • N6-Benzoyl-5′-O-DMT-adenosine, CAS 81246-82-4
  • 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine
  • 81246-82-4
  • C38H35N5O7