5'-DMT-RIBO ADENOSINE (N-BZ)

Product Name: 5'-DMT-RIBO ADENOSINE (N-BZ)
CAS No.: 81246-82-4
Chemical Name: 5'-DMT-RIBO ADENOSINE (N-BZ)
Synonyms: DMT-rA(Bz);N6-Bz-DMT-Ar;5'-DMT-Bz-rA;5'-O-DMT-Bz-rA;5'-O-DMT-N6-Bz Adenosine;N6-Bz-5'-O-DMT-adenosine;-DMT-RIBO ADENOSINE (N-BZ);5’-O-DMTr-Adenosine (N-bz);5'-DMT-RIBO ADENOSINE (N-BZ);5'-O-DMTr-N6-benzoyladenosine
CBNumber: CB4391155
Molecular Formula: C38H35N5O7
Formula Weight: 673.71
MOL File: 81246-82-4.mol

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5'-DMT-RIBO ADENOSINE (N-BZ) Property

Density: 1.36
storage temp.: Sealed in dry,2-8°C
form: Solid
pka: 7.87±0.43(Predicted)
color: White to off-white

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D494208
Product name: 5''-DMT-Bz-rA
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Ark Pharm

Product number: P000083611
Product name: 5'-DMT-Bz-rA
Purity: 95+%
Packaging: 250mg
Price: $8
Updated: 2021/12/16

Ark Pharm

Product number: P000083611
Product name: 5'-DMT-Bz-rA
Purity: 95+%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Ark Pharm

Product number: P000083611
Product name: 5'-DMT-Bz-rA
Purity: 95+%
Packaging: 5g
Price: $38
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NB07167
Product name: N6-Benzoyl-5'-O-DMT-adenosine
Packaging: 1g
Price: $65
Updated: 2021/12/16

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5'-DMT-RIBO ADENOSINE (N-BZ) Chemical Properties,Usage,Production

Uses

5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds?synthesis[1].

Synthesis

40615-36-9

4546-55-8

129666-75-7

The general procedure for the synthesis of the target compound (CAS: 129666-75-7) from 4,4'-dimethoxytrityl chloride (DMTrCl) and N6-benzoyl adenosine was as follows: to a pyridine solution (100 g, 269.3 mmol, 0.5 mmol) containing N-(9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl) at 0 °C, N-(9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl )-benzamide (100 g, 269.3 mmol) to a pyridine solution (500 mL) was added DMAP (1.64 g, 13.46 mmol, 0.05 equiv) and DMTrCl (100.4 g, 296.2 mmol, 1.1 equiv) in sequence. The reaction mixture was stirred at room temperature for 16 h. Upon completion of the reaction, the reaction was quenched by addition of methanol (500 mL). Volatiles were removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography (elution gradient: 1/1 petroleum ether/ethyl acetate to 100% ethyl acetate) to afford N-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzene Formamide, as a white foamy solid (150 g, 223 mmol, 83% yield).

References

[1] Boyu Zhong, et al. Cyclic di-nucleotide compounds and methods of use. Patent WO2017161349.

5'-DMT-RIBO ADENOSINE (N-BZ) Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-DMT-RIBO ADENOSINE (N-BZ) Suppliers

Canada 1 China 97 India 1 United Kingdom 2 United States 8 Global 109

A.J Chemicals

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View Lastest Price from 5'-DMT-RIBO ADENOSINE (N-BZ) manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4
Price: US $0.00-0.00/G
Min. Order: 1G
Purity: 98%
Supply Ability: 2000
Release date: 2025-06-04

Henan Aochuang Chemical Co.,Ltd.

Product: 5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

Career Henan Chemical Co

Product: 5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4?
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-21

81246-82-4, 5'-DMT-RIBO ADENOSINE (N-BZ)Related Search:

Diphenyldimethoxysilane 1,1-Dimethoxyethane 5'-Deoxyadenosylcobalamin Adenosine 2,6-Dimethoxybenzaldehyde ADENOSINE 5'-TRIPHOSPHATASE Benzoyl chloride Vidarabine Dimethyldimethoxysilane Benzoyl peroxide Dimethoxymethane N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-tert-butyldimethylsilyl guanosine 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine N-BENZOYLADENOSINE 5'-DMT-RIBO ADENOSINE (N-BZ)

N6-Benzoyl-5'-O-DMT-adenosine

DTN-006 5'-O-(4,4'-DiMethoxytrityl)-N6-benzoyl-adenosine

5'-DMT-Bz-rA

5'-O-DMT-N6-Bz Adenosine

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]adenosine

N6-Bz-DMT-Ar

5'-O-dimethoxytrityl-N6-benzoyl adenosine

N-[9-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]purin-6-yl]benzamide

Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-

5'-O-DMTr-N6-benzoyladenosine

N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-ADENOSINE

5'-DMT-RIBO ADENOSINE (N-BZ)

-DMT-RIBO ADENOSINE (N-BZ)

5'-O-DMT-Bz-rA

5'-DMT-RIBO ADENOSINE (N-BZ) USP/EP/BP

C38H35N5O7 5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4

5'-O-DMT-N6-Benzoyl-Adenosine

N6-Bz-5'-O-DMT-adenosine

N-(9-((2S,3S,4R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine

N-(9-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine

N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]purin-6-yl]benzamide

DMT-rA(Bz)

5'-DMT-RIBOADENOSINChemicalbookE(N-BZ)

5’-O-DMTr-Adenosine (N-bz)

N6-Benzoyl-5′-O-DMT-adenosine, CAS 81246-82-4

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine

81246-82-4

C38H35N5O7