L-Lactide

Product Name: L-Lactide
CAS No.: 4511-42-6
Chemical Name: L-Lactide
Synonyms: LACTIDE;L-LA;L-(-)-LACTIDE;LL-Lactide;L,L-Dilactide;(3S)-CIS-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONE;actide;-(-)-L;(3S,6S);L-LACTIDE
CBNumber: CB4416791
Molecular Formula: C6H8O4
Formula Weight: 144.13
MOL File: 4511-42-6.mol

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L-Lactide Property

Melting point:: 92-94 °C(lit.)
Boiling point:: 255°C
Density: 1.186±0.06 g/cm3(Predicted)
vapor pressure: 0.311Pa at 25℃
refractive index: 1.4475
storage temp.: 2-8°C
solubility: Soluble in chloroform, and methanol. Slightly soluble in benzene.
form: Solid
color: White to Off-White
optical activity: [α]20/D 285°, c = 1 in toluene
Water Solubility: 16.7g/L at 20℃
Sensitive: Moisture Sensitive
BRN: 82124
Stability:: Hygroscopic
InChIKey: JJTUDXZGHPGLLC-IMJSIDKUSA-N
LogP: 0.4 at 25℃
CAS DataBase Reference: 4511-42-6(CAS DataBase Reference)
EPA Substance Registry System: 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)- (4511-42-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-36
Safety Statements: 26-37/39
WGK Germany: 3
TSCA: Yes
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 367044
Product name: (3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione
Purity: 98%
Packaging: 25g
Price: $88.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 367044
Product name: (3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione
Purity: 98%
Packaging: 100g
Price: $307
Updated: 2024/03/01

TCI Chemical

Product number: L0115
Product name: L-(-)-Lactide
Purity: >98.0%(T)
Packaging: 25g
Price: $93
Updated: 2024/03/01

TCI Chemical

Product number: L0115
Product name: L-(-)-Lactide
Purity: >98.0%(T)
Packaging: 250g
Price: $557
Updated: 2024/03/01

Alfa Aesar

Product number: L09031
Product name: L-Lactide, 98+%
Packaging: 5g
Price: $27.65
Updated: 2024/03/01

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L-Lactide Chemical Properties,Usage,Production

Description

L-lactide (3,6-dimethyl-1,4-dioxane-2,5-dione) is a cyclic lactone that is derived from lactic acid. It has the molecular formula C3H6O2 and is an essential building block for synthesizing polylactic acid (PLA) plastics, which are widely used in the manufacturing industry.

Chemical Properties

White crystal

Uses

(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione may be used in the synthesis of optically active terpyridine containing poly(L-lactide)s, polydisperse lactic acid oligomers, bicyclic and tricyclic lactide derivatives.

Application

L-Lactide is a monomer used to produce polylactic acid (PLA), which is a biodegradable thermoplastic that has many uses in the pharmaceutical industry. Additionally, L-Lactide can be used to modify existing drug carriers or create new ones from scratch. As such, the pharmaceutical industry relies heavily on L-Lactide for its versatile applications.

Flammability and Explosibility

Non flammable

Purification Methods

This is the cyclic dilactone of lactic acid. The (±)-cis-racemate has been distilled with b 142o/8mm; the distillate which solidifies gives yellow needles on recrystallisation from EtOH with m 128o, from Et2O with m 129o, or CHCl3 with m 126o , 1720-1740 cm-1. It hydrolyses in cold max H2O. [Carothers et al. J Am Chem Soc 54 772 1932]. A trans-form (probably RS,SR) has been reported which crystallises from Et2O with m 42-43o [Hummel et al. Acta Cryst (Sect B) 38 1679 1982]. The R,R -(+)-lactide has b 150o/2mm and crystallises from Et2O with m 95o , or m 96.5 -97.5o (from CHCl3) or m 97.7o (from EtOAc) and [] D +297o (c 1.2, *C6H6). The S,S-(-)-lactide has b 150o/2.5mm and crystallises from EtOAc with m 98.7o, or m 95o (from CHCl3) or m 96.5-97.5o (from CCl4) and []D -297o (c 1.2, *C6H6). [Toniolo et al. J Org Chem 35 6 1970, Beilstein 19 H 154, 19 I 179, 19 II 176, 19 IV 1927, 19/5 V 10.]

L-Lactide Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl lactate Butyl lactate

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L-Lactide Suppliers

Americas 1 China 258 China Hong Kong 1 Europe 1 Germany 3 India 7 Japan 4 Poland 1 Switzerland 1 Ukraine 1 United Kingdom 5 United States 22 Global 305

Accela ChemBio Inc.

Tel: +1-858-6993322
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Aladdin Scientific

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Monomer Polymer & Dajac Labs

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Frinton Laboratories Inc.,

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Alichem Inc.

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United States Biological

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Combi-Blocks Inc.

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Frontier Scientific, Inc.

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Matrix Scientific

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CarboMer, Inc.

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Frinton Laboratories, Inc.

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Alfa Aesar

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HONEST JOY HOLDINGS LIMITED

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3B Scientific Corporation

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Pfaltz & Bauer, Inc.

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Polysciences, Inc.

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Richman Chemical Inc.

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Purac America, Inc.

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Monomer-Polymer & Dajac Laboratories, Inc.

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View Lastest Price from L-Lactide manufacturers

Hebei Longbang Technology Co., Ltd

Product: L-Lactide 4511-42-6
Price: US $6.00/kg
Min. Order: 1kg
Purity: More than 99%
Supply Ability: 2000KG/Month
Release date: 2024-05-27

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: L-Lactide 4511-42-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-08

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: L-(-)-Lactide 4511-42-6
Price: US $70.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-06-04

4511-42-6, L-LactideRelated Search:

Dimethyl carbonate Cyclohexane ETHANE Dimethyl sulfoxide Hexane Dimethyl fumarate Dimethyl ether N,N-Dimethylformamide Cyclohexene oxide Methylcyclohexane 1,4-Dioxane L-Homoserine lactone hydrochloride POLY(D,L-LACTIDE-CO-GLYCOLIDE) LACTIDE(D,L-),DL-LACTIDE,LACTIDE 2-hydroxypropionicacid,isopropylester 1,4-Dioxane-2,5-dione (S)-(-)-2-ACETOXYPROPIONIC ACID ETHYL (S)-(-)-2-METHOXYPROPIONATE

L-3,6-Dimethyl-1,4-dioxane-2,5-dione

1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)-

3,6-dimethyl-1,4-dioxane-2,5-quinone

actide

L-(-)-LACTIDE 98+%

3,6-Dimethyl-2,5-p-dioxanedione

L-(-)-Lactide ,99%

L,L-Dilactide

L-3,6-DiMethyl-p-dioxane-2,5-dione

LL-Lactide

L-(-)-Dilactide (3S,6S)-(-)-3,6-Dimethyl-1,4-dioxane-2,5-dione

L(-)-Lactide USP

(3S)-cis-3,6-DiMethyl-1,4-dioxane-2,5-dione 98%

<small>L</small>-(-)-Lactide

(3S,6S)

(3S)-CIS-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONE

(3S,6S)-(-)-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONE

L-LACTIDE S

L-(-)-LACTIDE

L-LACTIDE

LACTIDE

LACTIDE(L-)

L-(-)-DILACTIDE

PURASORB(R) L

5-dione,3,6-dimethyl-,(3s,6s)-4-dioxane-2

(S,S)-3,6-Dimethyl-1,4-dioxane-2,5-dione

L-LA

L-(-)-Lactide&gt

L-(-)-Dilactide,99%+

(3S-cis)-3,6-Dimethyl-1,4-dioxan-2,5-dion

-(-)-L

Biomaterial Intermediate Monomer L-Lactide (LLA) CAS No.:?4511-42-6

Polyhexamethyleneguanidine hydrochloride 57028-96-3

L-lactide/L-lactide (with details)

Aaron chemistry

4511-42-6

4551-42-6

Asymmetric Synthesis

Glycidyl Compounds, etc. (Chiral)

Lactones & Lactides (for High-Performance Polymer Research)

Dioxanes

Chiral Building Blocks

Dioxanes & Dioxolanes

Reagent for High-Performance Polymer Research

Organic Building Blocks

Lactones

Chiral Building Blocks

Dioxanes

Dioxanes & Dioxolanes

Functional Materials

Glycidyl Compounds, etc. (Chiral)

Lactones & Lactides (for High-Performance Polymer Research)

Reagent for High-Performance Polymer Research

Synthetic Organic Chemistry

4511-42-6