L-Homoserine lactone hydrochloride
- Product Name
- L-Homoserine lactone hydrochloride
- CAS No.
- 2185-03-7
- Chemical Name
- L-Homoserine lactone hydrochloride
- Synonyms
- HSL;LHS;AOMS4;FPLD6;LSHLO.HCl;95.0%(N&-Homoserine L;HSE LACTONE HCL;actone hydrochL;L-Amino lactone
- CBNumber
- CB0252683
- Molecular Formula
- C4H8ClNO2
- Formula Weight
- 137.56
- MOL File
- 2185-03-7.mol
L-Homoserine lactone hydrochloride Property
- Melting point:
- 210-220 °C (dec.)(lit.)
- alpha
- -25 º (c=0.5, water)
- refractive index
- -26 ° (C=0.2, H2O)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Pale Beige
- biological source
- rabbit
- optical activity
- [α]20/D 27.8°, c = 1 in H2O
- Water Solubility
- soluble
- BRN
- 3562187
- InChI
- InChI=1/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/s3
- InChIKey
- XBKCXPRYTLOQKS-DFWYDOINSA-N
- SMILES
- [C@H]1(N)CCOC1=O.Cl |&1:0,r|
- CAS DataBase Reference
- 2185-03-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- F
- 3-10
- HS Code
- 29322090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- HPA006567
- Product name
- Anti-LIPE antibody produced in rabbit
- Purity
- Prestige Antibodies<SUP>®</SUP> Powered by Atlas Antibodies, affinity isolated antibody
- Packaging
- 100 μL
- Price
- $555
- Updated
- 2025/07/31
- Product number
- 459224
- Product name
- (S)-α-Amino-γ-butyrolactone hydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $79.45
- Updated
- 2025/07/31
- Product number
- A1445
- Product name
- (S)-(-)-alpha-Amino-gamma-butyrolactone Hydrochloride
- Purity
- >95.0%(N)(T)
- Packaging
- 1g
- Price
- $158
- Updated
- 2025/07/31
- Product number
- H7015-30
- Product name
- L-Homoserine Lactone, Hydrochloride
- Packaging
- 1g
- Price
- $425
- Updated
- 2021/12/16
- Product number
- H615100
- Product name
- L-HomoserineLactone,Hydrochloride
- Packaging
- 50g
- Price
- $425
- Updated
- 2021/12/16
L-Homoserine lactone hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
(S)-α-Amino-γ-butyrolactone hydrochloride can be used:
- As a precursor for the preparation of amino-keto-alcohols and β-amino acids.
- To prepare N-acylhomoserine lactone (AHL) analogs by reacting with substituted 2-chloro-N-phenylacetamide and different halides.
- As a starting material for the synthesis of L-discadenine.
Synthesis
672-15-1
2185-03-7
The general procedure for synthesizing L-homoserine lactone hydrochloride from L-homoserine is as follows: mix L-homoserine (0.84 mol) with 600 mL of concentrated hydrochloric acid (6.1 mol). The reaction mixture was stirred for about 15 minutes until all solids were completely dissolved. Subsequently, the water was removed by distillation under reduced pressure over a period of 1.5 hours. Finally, the residue was dried. The yield of this step was 99% to give 2-amino-4-butyrolactone hydrochloride.
References
[1] Patent: US7368600, 2008, B2. Location in patent: Page/Page column 16-17
[2] Tetrahedron Asymmetry, 1995, vol. 6, # 11, p. 2819 - 2828
[3] Patent: US2011/53890, 2011, A1. Location in patent: Page/Page column 3
[4] Journal of Organic Chemistry, 2016, vol. 81, # 11, p. 4516 - 4529
[5] Tetrahedron Letters, 2010, vol. 51, # 50, p. 6500 - 6502
L-Homoserine lactone hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-Homoserine lactone hydrochloride manufacturers
- Product
- L-Homoserine lactone hydrochloride 2185-03-7
- Price
- US $1.00/kg
- Min. Order
- 0.001kg
- Purity
- 99.99%
- Supply Ability
- 200000T
- Release date
- 2025-06-06
- Product
- L-Homoserine Lactone hydrochloride 2185-03-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-19
- Product
- L-Homoserine lactone hydrochloride 2185-03-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11