Levosulpiride

Product Name: Levosulpiride
CAS No.: 23672-07-3
Chemical Name: Levosulpiride
Synonyms: Levosulpride;l-Form;rv-12309;Levopride;levopraid;l-Sulpirid;levosupride;l-Sulpiride;LEVOSULPIRIDE;(S)-(-)-Sulpir
CBNumber: CB4422019
Molecular Formula: C15H23N3O4S
Formula Weight: 341.43
MOL File: 23672-07-3.mol

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Levosulpiride Property

Melting point:: 183-186 °C(lit.)
Density: 1.236±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 9.98±0.60(Predicted)
form: Solid
color: White to Off-White
Merck: 14,8989
InChIKey: BGRJTUBHPOOWDU-NSHDSACASA-N
CAS DataBase Reference: 23672-07-3(CAS DataBase Reference)

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Safety

RIDADR: 3077
WGK Germany: 3
RTECS: BZ3400100
HS Code: 29350090
Toxicity: LD50 oral in rabbit: > 1500mg/kg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S7771
Product name: (S)-(?)-Sulpiride
Purity: ≥98% (titration)
Packaging: 5g
Price: $96.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 34002
Product name: (S)-(−)-Sulpiride
Purity: VETRANAL?, analytical standard
Packaging: 100mg
Price: $145
Updated: 2024/03/01

Sigma-Aldrich

Product number: 5.05626
Product name: (S)-Sulpiride - CAS 23672-07-3 - Calbiochem
Packaging: 100mg
Price: $82.2
Updated: 2022/05/15

TCI Chemical

Product number: I0821
Product name: (S)-(-)-Sulpiride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $108
Updated: 2024/03/01

TCI Chemical

Product number: I0821
Product name: (S)-(-)-Sulpiride
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $271
Updated: 2024/03/01

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Levosulpiride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

(S)-(?)-Sulpiride was used to study the effect of dopamine D₂ receptor function on activation of KCNQ potassium channels¹⁰ and on depression-like behavior in ovariectomized female rats.¹¹

Uses

dopamine receptor antagonists

Uses

Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.

Definition

ChEBI: An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, 1 and D5 receptors respectively).

General Description

(S)-(?)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.

Biological Activity

Active enantiomer. Selective D 2 -like dopamine antagonist (K i values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 μ M at D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively).

Biochem/physiol Actions

(S)-(?)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(?)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9

storage

Room temperature

Levosulpiride Preparation Products And Raw materials

Raw materials

Lithium tert-butoxide Ethanol Aminosulfonate Sulpiride (S)-2-(Aminomethyl)-1-ethylpyrrolidine 2-(Aminomethyl)-1-ethylpyrrolidine L-Proline Lithium Aluminum Hydride Sodium hydroxide L(+)-Tartaric acid Methyl benzoate

Preparation Products

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Levosulpiride Suppliers

Americas 1 Argentina 1 Belgium 1 Brazil 1 Canada 4 China 212 Europe 3 Germany 7 India 107 Italy 3 Japan 3 Poland 1 South Korea 8 Switzerland 1 The Netherlands 1 United Kingdom 20 United States 50 Global 424

Merck Millipore

Tel: --
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Email: ccc@merckgroup.com
Country: Germany
ProdList: 2008
Advantage: 58

CHEMOS GmbH & Co. KG

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Email: chemos@chemos.de
Country: Germany
ProdList: 6727
Advantage: 58

Burmester Pharmatrade Gmbh

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Email: info@burmester-pharma.de
Country: Germany
ProdList: 1347
Advantage: 58

ChemPur GmbH

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Email: info@ChemPur.de
Country: Germany
ProdList: 2737
Advantage: 50

Dr. Ehrenstorfer GmbH

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Email: info@analytical-standards.com
Country: Germany
ProdList: 5545
Advantage: 66

ratiochem GmbH

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Email: info@ratiochem.org
Country: Germany
ProdList: 310
Advantage: 34

BIOTREND Chemicals AG

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Email: info@biotrend.ch
Country: Germany
ProdList: 1250
Advantage: 62

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View Lastest Price from Levosulpiride manufacturers

Hong Kong Excellence Biotechnology Co., Ltd.

Product: Levosulpiride 23672-07-3
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-10-12

Sigma Audley

Product: Levosulpiride 23672-07-3
Price: US $35.00-25.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 200tons/year
Release date: 2024-03-15

Sigma Audley

Product: Levosulpiride 23672-07-3
Price: US $45.00-35.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 200tons/year
Release date: 2024-01-16

23672-07-3, LevosulpirideRelated Search:

METSULFURON METHYL Bensulfuron methyl Amisulpride Thiophanate-methyl Methyl acetate Chlorantraniliprole Methyl acrylate Benzamide Kresoxim-methyl Methylparaben Calcium levofolinate Levomilnacipran Levothyroxine sodium L(+)-Tartaric acid Methyl L(-)-Carvone Levodopa L(-)-Carnitine hydrochloride

(s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide

(s)-(-)-o-anisamid

(S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide

China (S)-(-)-Sulpiride

Levosulpiride, (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

S-(-)-Sulpiride，Levobren，Levopraid

(s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide 5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid ( s-(-)-benzamid

rv-12309 s-(-)-n-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide

s-(-)-sulpiride (S)--5-Aminosulfonyl-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide

levosupride

(S)-(-)-5-(Aminoulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

Levopride

5-(AMinosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]Methyl]-2-Methoxy-benzaMide

5-(AMinosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]Methyl]-2-benzaMide

l-Sulpirid

(S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide Levosulpiride

(S)-(-)-5-(aMinosulfonyl)-N-[(1-ethyl-2-pyrrolinyl)Methyl]

Levosulpiride (Irritable Bowel SyndroMe)

(S)-(-)-Sulpir

(S)-(-)-SULPIRIDE

(S)-(-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE

5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid(

levopraid

rv-12309

s-(-)-n-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide

(-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXY-BENZAMIDE

Levosulpride

(S)-(-)-Sulpiride, Vetranal

S(-)-SULPIRIDE DOPAMINE D1 ANTAGONIS

LEVOSULPIRIDE/LEVOSULPRIDE

Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, (S)-

Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy- (9CI)

l-Sulpiride

(S)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE

(-)-N-1-[ETHYLPYRROLIDIN-2-YLMETHYL]-2-METHOXY-5-SULFAMOYLBENZAMIDE

LEVOSULPIRIDE

(S)-(-)-Sulpiride, 98%, a selective antagonist for D2 dopamine receptor

l-Form

LEVOSULPIRIDE (RV-12309)

Left-handed sulpiride

(S)-(-)-Sulpiride&gt

Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-

Levosulpiride USP/EP/BP

L-Sulpiride Impurity

LevosulpirideQ: What is Levosulpiride Q: What is the CAS Number of Levosulpiride Q: What is the storage condition of Levosulpiride Q: What are the applications of Levosulpiride

LevosulprideQ: What is Levosulpride Q: What is the CAS Number of Levosulpride

Lform of Sulpiride

Levosulpiride (S)-(-)-Sulpiride

LEVOSULPRIDE 60% SR PELLETS

Caprylic Acid Impurity 36

(S)-Sulpiride, D2-like dopamine antagonist

23672-07-3

C15H23N3O4O4

Analytical Standards

Analytical Chromatography Product Catalog

Alphabetic

SN - SZ

Dopamine receptor