Pheophorbide A

Product Name: Pheophorbide A
CAS No.: 15664-29-6
Chemical Name: Pheophorbide A
Synonyms: PHEOPHORBIDE A;Phaeophorbide A;Pheophorbide A (>13-Epi-phaeophorbide-a;Chlorophyll Impurity 2;pheophorbide a AldrichCPR;Demagnesia chloric acid -a;Pheophorbide a (mixture of diastereomers);[3s-(3alpha,4beta,21beta)]-ramethyl-20-oxo;Pheophorbide A (>80%) (mixture of diastereomers)
CBNumber: CB4426628
Molecular Formula: C35H36N4O5
Formula Weight: 592.7
MOL File: 15664-29-6.mol

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Pheophorbide A Property

Melting point:: 191-195 °C
Boiling point:: 1019.0±65.0 °C(Predicted)
Density: 1.282±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO: soluble0.5mg/mL, clear (warmed)
form: Solid
color: blue, to dark brown to black
Stability:: Light Sensitive
EPA Substance Registry System: 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-, (3S,4S,21R)- (15664-29-6)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1218
Product name: Pheophorbide-a
Purity: ≥90% (HPLC)
Packaging: 10MG
Price: $54.2
Updated: 2023/06/20

Cayman Chemical

Product number: 16072
Product name: Pheophorbide a
Purity: ≥90% (mixture of diastereomers)
Packaging: 25mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 16072
Product name: Pheophorbide a
Purity: ≥90% (mixture of diastereomers)
Packaging: 50mg
Price: $130
Updated: 2024/03/01

Cayman Chemical

Product number: 16072
Product name: Pheophorbide a
Purity: ≥90% (mixture of diastereomers)
Packaging: 100mg
Price: $241
Updated: 2024/03/01

TRC

Product number: P998428
Product name: PheophorbideA(>80%)(mixtureofdiastereomers)
Packaging: 50mg
Price: $520
Updated: 2021/12/16

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Pheophorbide A Chemical Properties,Usage,Production

Uses

Pheophorbide a is a chlorophyll-related compound studied for it’s anti-tumor & anti-cancer activity.

Uses

Pheophorbide-a has been used as a photosensitizer:

for the photodynamic therapy (PDT) in oral cancer cell lines
to test its effect on inducing oxidative stress and death in L. amazonensis
to test its effect on the viability of HeLa cells

Definition

ChEBI: Pheophorbide a is a pheophorbide. It is a conjugate acid of a pheophorbide a(2-).

Biochem/physiol Actions

Pheophorbide-a, due to its photosensitizing effect, may serve as a promising bioactive compound to treat leishmaniasis. It is a metabolite of chlorophyll and possesses immunostimulation functionality. Pheophorbide-a is a photosensitizer for the photodynamic therapy. It is an ATP Binding Cassette Subfamily G Member 2 (ABCG2) transporter specific substrate. Overexpression of ATP-binding cassette (ABC) transporters in cancer cells is associated with the multidrug resistance phenotype.

Enzyme inhibitor

This chlorophyll a degradation intermediate (MW = 579.68 g/mol; CAS 15664-29-6), which is identical to chlorophyll a, except for the absence of the latter’s magnesium ion and ester at the 17-position, is obtained by acid hydrolysis of chlorophyll a. Pheophorbide a inhibits acyl-CoA:cholesterol acyltransferase and magnesium protoporphyrin IX methyltransferase, acts as an endothelin receptor antagonist, and also induces apoptosis. Pheophorbide a is also as an anti-tumor promoter.

Pheophorbide A Preparation Products And Raw materials

Raw materials

Preparation Products

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Pheophorbide A Suppliers

China 69 Germany 1 India 5 Japan 1 United Kingdom 1 United States 13 Global 90

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View Lastest Price from Pheophorbide A manufacturers

Career Henan Chemical Co

Product: Pheophorbide A 15664-29-6
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

15664-29-6, Pheophorbide ARelated Search:

Ethyl pyruvate Ethyl acrylate ISOXADIFEN-ETHYL Ethyl acetate Ethanol Ethylparaben Ethyl formate Ethyl cyanoacetate Methyl pheophorbide b Methyl pheophorbide a Sodium pheophorbide a PHEOPHYTIN A 1-(4-Methyl-1H-pyrrol-3-yl)ethanone PHEOPHYTIN B Pheophorbide A vanadyl pheophorbide complex pheophorbide b N-(2-methylethyl)pheophorbide

PHEOPHORBIDE A

[3s-(3alpha,4beta,21beta)]-ramethyl-20-oxo

3-phorbinepropanoicacid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tet

[3S-(3alpha,4beta,21beta)]-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic acid

(3S,4S)-9-Ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid

13-Epi-phaeophorbide-a

3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-

Inchi=1/C35H36N4o5/C1-8-19-15(3)22-12-24-17(5)21(10-11-28(40)41)32(38-24)30-31(35(43)44-7)34(42)29-18(6)25(39-33(29)30)14-27-20(9-2)16(4)23(37-27)13-26(19)36-22/H8,12-14,17,21,31,36,39H,1,9-11H2,2-7H3,(H,40,41)/B22-12-,23-13-,24-12-,25-14-,26-13-,27-14-

Rel-3-[(3R,4R)-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid

pheophorbide a AldrichCPR

Phaeophorbide A

Pheophorbide a (mixture of diastereomers)

Demagnesia chloric acid -a

Chlorophyll Impurity 2

Pheophorbide A (&gt

3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-, (3S,4S,21R)-

Pheophorbide A (>80%) (mixture of diastereomers)

15664-29-6

C35H36N4O5

Natural Porphyrins and Derivitives

Porphyrins

Elisa Kit-plant ELISA Kit