5-Chloro-8-hydroxyquinoline
- Product Name
- 5-Chloro-8-hydroxyquinoline
- CAS No.
- 130-16-5
- Chemical Name
- 5-Chloro-8-hydroxyquinoline
- Synonyms
- Cloxyquin;Cloxiquin;cloxiquine;5-CHLORO-8-QUINOLINOL;Cloxyqui;Chlorisept;Cloxyquine;Dermofungin;DERMOFONGIN;5-CHLOROOXINE
- CBNumber
- CB4434834
- Molecular Formula
- C9H6ClNO
- Formula Weight
- 179.6
- MOL File
- 130-16-5.mol
5-Chloro-8-hydroxyquinoline Property
- Melting point:
- 122-124 °C(lit.)
- Boiling point:
- 348.7±22.0 °C(Predicted)
- Density
- 1.2364 (rough estimate)
- vapor pressure
- 0.003Pa at 25℃
- refractive index
- 1.5330 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 0.019g/l (experimental)
- form
- Powder
- pka
- 3.77±0.10(Predicted)
- color
- Light green to gray
- Sensitive
- Light Sensitive
- Merck
- 14,2422
- BRN
- 5289
- InChIKey
- RWPWQYXFGFYJBA-UHFFFAOYSA-N
- CAS DataBase Reference
- 130-16-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 8-Quinolinol, 5-chloro-(130-16-5)
- EPA Substance Registry System
- 8-Quinolinol, 5-chloro- (130-16-5)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- RTECS
- VC4590000
- TSCA
- Yes
- HS Code
- 29334990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C47000
- Product name
- 5-Chloro-8-quinolinol
- Purity
- 95%
- Packaging
- 100g
- Price
- $68.6
- Updated
- 2024/03/01
- Product number
- C0645
- Product name
- 5-Chloro-8-hydroxyquinoline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $36
- Updated
- 2024/03/01
- Product number
- C0645
- Product name
- 5-Chloro-8-hydroxyquinoline
- Purity
- >98.0%(GC)(T)
- Packaging
- 250g
- Price
- $158
- Updated
- 2024/03/01
- Product number
- B22856
- Product name
- 5-Chloro-8-hydroxyquinoline, 95%
- Packaging
- 50g
- Price
- $35.65
- Updated
- 2024/03/01
- Product number
- B22856
- Product name
- 5-Chloro-8-hydroxyquinoline, 95%
- Packaging
- 250g
- Price
- $88.65
- Updated
- 2024/03/01
5-Chloro-8-hydroxyquinoline Chemical Properties,Usage,Production
Chemical Properties
light green to grey powder
Uses
antibacterial, antifungal
Uses
Dermofungin, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.
Definition
ChEBI: Cloxiquine is a member of quinolines and an organochlorine compound.
Synthesis Reference(s)
The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x
in vitro
Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis .
Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.|
Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.
Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
in vivo
Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.
Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
5-Chloro-8-hydroxyquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
5-Chloro-8-hydroxyquinoline Suppliers
- Tel
- --
- Fax
- --
- info@marjinalco.com.tr
- Country
- Turkey
- ProdList
- 50
- Advantage
- 58
View Lastest Price from 5-Chloro-8-hydroxyquinoline manufacturers
- Product
- 5-Chloro-8-hydroxyquinoline 130-16-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-31
- Product
- 5-Chloro-8-hydroxyquinoline 130-16-5
- Price
- US $20.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-01
- Product
- 5-Chloro-8-hydroxyquinoline 130-16-5
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2024-04-10