ChemicalBook > CAS DataBase List > 2-Amino-6-fluoropyridine

2-Amino-6-fluoropyridine

Product Name
2-Amino-6-fluoropyridine
CAS No.
1597-32-6
Chemical Name
2-Amino-6-fluoropyridine
Synonyms
6-Fluoropyridin-2-amine;6-FLUORO-PYRIDIN-2-YLAMINE;EOS-60628;6-Fluoro-2-pyridinamine;2-AMINO-6-FLUOROPYRIDINE;2-Fluoro-6-aminopyridine;2-Pyridinamine, 6-fluoro-;2-AMino-6-fluoropyriMidine;2-Amino-6-fluoropyridine >2-Amino-6-fluoropyridine 98%
CBNumber
CB4438746
Molecular Formula
C5H5FN2
Formula Weight
112.11
MOL File
1597-32-6.mol
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2-Amino-6-fluoropyridine Property

Melting point:
59-61°C
Boiling point:
225.0±20.0 °C(Predicted)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.26±0.24(Predicted)
color 
White to Almost white
InChI
InChI=1S/C5H5FN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)
InChIKey
UZALKVXCOUSWSL-UHFFFAOYSA-N
SMILES
C1(N)=NC(F)=CC=C1
CAS DataBase Reference
1597-32-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
725064
Product name
2-Amino-6-fluoropyridine
Purity
98%
Packaging
1g
Price
$46.8
Updated
2023/06/20
Sigma-Aldrich
Product number
725064
Product name
2-Amino-6-fluoropyridine
Purity
98%
Packaging
5g
Price
$173
Updated
2023/06/20
TCI Chemical
Product number
A2879
Product name
2-Amino-6-fluoropyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$50
Updated
2025/07/31
TCI Chemical
Product number
A2879
Product name
2-Amino-6-fluoropyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$151
Updated
2025/07/31
TRC
Product number
F596293
Product name
6-Fluoropyridin-2-amine
Packaging
500mg
Price
$65
Updated
2021/12/16
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2-Amino-6-fluoropyridine Chemical Properties,Usage,Production

Description

2-Amino-6-fluoropyridine is an organic intermediate that can be prepared via the nucleophilic substitution reaction of 2,6-difluoropyridine with ammonia.

Uses

2-Amino-6-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

1513-65-1

1597-32-6

The general procedure for the synthesis of 2-amino-6-fluoropyridine from 2,6-difluoropyridine was as follows: 2,6-difluoropyridine (50 g, 434 mmol) was dissolved in ammonium hydroxide solution (200 mL, 28.0-30.0%) in a steel tube and the reaction was heated for 15 hr at 105 °C. Upon completion of the reaction, the mixture was cooled in an ice bath and the precipitate was subsequently collected by filtration. The precipitate was washed with cold water and dried to give 6-fluoro-2-pyridinamine (45.8 g, 94% yield) as a white solid. The structure of the product was confirmed by 1H-NMR (CDCl3): δ 7.53 (m, 1H), 6.36 (dd, 1H), 6.26 (dd, 1H), 4.56 (s, 2H).

References

[1] Patent: WO2006/76131, 2006, A2. Location in patent: Page/Page column 39-40
[2] Patent: WO2007/27999, 2007, A2. Location in patent: Page/Page column 35
[3] Patent: WO2006/36816, 2006, A2. Location in patent: Page/Page column 59-60
[4] Patent: WO2006/26703, 2006, A2. Location in patent: Page/Page column 64-65
[5] Patent: WO2007/87549, 2007, A2. Location in patent: Page/Page column 44; 59

2-Amino-6-fluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-6-fluoropyridine Suppliers

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View Lastest Price from 2-Amino-6-fluoropyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Amino-6-fluoropyridine 1597-32-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26
Career Henan Chemical Co
Product
2-Amino-6-fluoropyridine 1597-32-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-09

1597-32-6, 2-Amino-6-fluoropyridineRelated Search:

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  • 6-FLUORO-PYRIDIN-2-YLAMINE
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  • 2-Amino-6-fluoropyridine ISO 9001：2015 REACH
  • 1597-32-6
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