ChemicalBook > CAS DataBase List > 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one

8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one

Product Name
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
CAS No.
31251-41-9
Chemical Name
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
Synonyms
8-Chloro-10;Keto loratadine;Loratad Impurity B;2-b]pyridin-11-one;D] cycloheptan-5-one;Loratadine impurity B;6-dihydro-11H-benzo[5;Loratadine tricycline;Loratadine EP IMpurity B;Loratadine Impurity B（EP ）
CBNumber
CB4456713
Molecular Formula
C14H10ClNO
Formula Weight
243.69
MOL File
31251-41-9.mol
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8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Property

Melting point:
90-92°C
Boiling point:
433.6±45.0 °C(Predicted)
Density 
1.313±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
3.14±0.20(Predicted)
color 
Pale Yellow to Pale Brown
CAS DataBase Reference
31251-41-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
HS Code 
2933997500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2309
Product name
Loratadine Related Compound C
Purity
Pharmaceutical Secondary Standard; Certified Reference Standard
Packaging
50MG
Price
$608
Updated
2024/03/01
Sigma-Aldrich
Product number
1370269
Product name
Loratadine Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
C3181
Product name
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$155
Updated
2024/03/01
TCI Chemical
Product number
C3181
Product name
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$387
Updated
2024/03/01
TRC
Product number
C365245
Product name
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
Packaging
500mg
Price
$135
Updated
2021/12/16
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8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one (Loratadine EP Impurity B; Loratadine USP Related Compound C) is a Loratadine intermediate. Loratidine impurity C.

8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Preparation Products And Raw materials

Raw materials

Preparation Products

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8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Suppliers

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View Lastest Price from 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 31251-41-9
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
100KGS
Release date
2021-06-05
Henan Aochuang Chemical Co.,Ltd.
Product
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 31251-41-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10
Career Henan Chemical Co
Product
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 31251-41-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-12-25

31251-41-9, 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-oneRelated Search:

Pyridine hydrobromide Copper Pyrithione 2-Chloro-3-cyanopyridine Zinc pyrithione Benzo[b]thien-2-ylboronic acid Clopidol Pentachloropyridine Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Pyridine hydrofluoride 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecarbonitrile 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one (Loratadine Impurity) 3-Hydroxy loratadine Loratadine EP IMpurity F Loratadine Impurity 17 Loratadine Impurity 13 Loratadine Impurity 13 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Loratadine Impurity 15

  • 8-CHLORO-5,6-DIHYDRO-11H-BENZO-(5,6)-CYCLOHEPTA-(1,2-B)-PYRIMIDINE-11-ON
  • 8-Chloro-10,11-dihydro-4-aza-5
  • 8-chloro-10,11-dihydro-4-AZA-5H-benzo〔A,D〕cyclohepta-5-one
  • 8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIMIDINE-11-ONE
  • 4-Aza-8-chloro-10,11-dihydro-5H-benzo[a,d]cyclo-5-heptanone
  • 8-CHLORO-10,11-DIHYDRO-4 AZA-5H-BENZO[A,D] CYCLOHEPTAN-5-ONE =98%
  • 8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-ONE
  • 8-CHLORO-10,11-DIHYDRO-4-AZA-5H-DIBENZO-(A,D)CYCLOHEPTAN-5-ONE
  • 8-CHLORO-10,11-DIHYDRO-4-AZA-5H-BENZO[A,D] CYCLOHEPTAN-5-ONE
  • 8-CHLORO-6,11-DIHYDRO-11-(1-METHYL-4-PIPERIDYLEDENE)-5H-BENZO(5,6)-CYCLOHEPTA(1,2,B)PYRIDINE
  • 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one
  • 11-dihydro-4-aza-5H-benzo[A
  • 8-Chloro-10
  • D] cycloheptan-5-one
  • 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclo hepta[1,2-b]pyridin-11-
  • Loratadine Related Compound C (15 mg) (8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one)
  • Loratadine EP IMpurity B
  • Loratadine Related CoMpound C
  • 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one,8-chloro-5,6-dihydro-
  • Loratadine impurity B
  • 8-Chloro-5,6-dihydro-11<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]pyridin-11-one
  • Keto loratadine
  • Loratadine Impurity 2(Loratadine EP Impurity B)
  • Loratad Impurity B
  • 8-Chloro-5,6-dihydro-11H-benzo[5.6]
  • 4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclo-
  • 2-b]pyridin-11-one
  • 6-dihydro-11H-benzo[5
  • 8-Chloro-10,11-dihydro-4-AZA-5H-dibenzo(a,d)- Cyclohepten-5-One(or)(Loraketone)
  • 13-chloro-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-one
  • 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one (Desloratadine Impurity)
  • Loratidine EP Impurity B/ Loratidine Related Compound C
  • 8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptan-5-on...
  • Loratadine Related Compound C (8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one) (1370269)
  • Loratadine Impurity B（EP ）
  • Loratadine USP Related Compound C
  • 8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
  • 8-Chloro-10,11-dihydro-4-aza-5H-dibenzo (a,d)ycloheptan-5-one
  • 2-chloromethyl-3-methy1-4-(2,2,2- triflu oroethoxy) pyridine hydrochloride
  • Loratadine tricycline
  • 8-chloro-5,6-dihydro-11H-benzo [5,6] cycloheptano [1,2-b] pyridin-11 one
  • 8-chloro-10,Chemicalbook11-dihydro-4-AZA-5H-benzo〔A,D〕cyclohepta-5-one
  • Loratadine EP Impurity B (Loratadine USP Related Compound C)
  • 13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one
  • 31251-41-9
  • 31521-41-9
  • C14H10ClNO
  • Aromatics
  • Heterocycles
  • Intermediates
  • Aromatics Compounds