ChemicalBook > CAS DataBase List > 2,4,6-Trifluorobenzoic acid

2,4,6-Trifluorobenzoic acid

Product Name
2,4,6-Trifluorobenzoic acid
CAS No.
28314-80-9
Chemical Name
2,4,6-Trifluorobenzoic acid
Synonyms
2,4,6-TrifL;BUTTPARK 44\01-13;2,4,6-TRIFLUOROBEN;TIMTEC-BB SBB006688;RARECHEM AL BO 0448;Lasmiditan Impurity;2,4,6-Trifluorobenzo;Lamidipan Impurity 1;2,4,6-Trifluorobenzoic;2,4,6-TRIFLUOROBENZOIC ACID
CBNumber
CB4463593
Molecular Formula
C7H3F3O2
Formula Weight
176.09
MOL File
28314-80-9.mol
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2,4,6-Trifluorobenzoic acid Property

Melting point:
142-145 °C (lit.)
Boiling point:
218.2±35.0 °C(Predicted)
Density 
1.4362 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.28±0.10(Predicted)
color 
White to Light yellow
BRN 
1958300
InChIKey
SJZATRRXUILGHH-UHFFFAOYSA-N
CAS DataBase Reference
28314-80-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2409
Product name
2,4,6-Trifluorobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$51
Updated
2024/03/01
Alfa Aesar
Product number
A19758
Product name
2,4,6-Trifluorobenzoic acid, 98%
Packaging
1g
Price
$46.65
Updated
2024/03/01
Alfa Aesar
Product number
A19758
Product name
2,4,6-Trifluorobenzoic acid, 98%
Packaging
5g
Price
$156.65
Updated
2024/03/01
TRC
Product number
T792653
Product name
2,4,6-Trifluorobenzoic Acid
Packaging
1g
Price
$40
Updated
2021/12/16
Matrix Scientific
Product number
003636
Product name
2,4,6-Trifluorobenzoic acid
Purity
98%
Packaging
25g
Price
$49
Updated
2021/12/16
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2,4,6-Trifluorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

2,4,6-Trifluorobenzoic Acid is used in preparation of Difluorophenol.

Application

The 2,4,6-Trifluorobenzoic acid is crucial and an important raw material for preparing the photosensitizers, medicines and pesticides, and also finds applications in pharmaceutical and agrochemical industries.

General Description

2,4,6-Trifluorobenzoic acid is a fluorobenzoic acid. Crystal structure of 2,4,6-trifluorobenzoic acid has been studied.

Synthesis

Add 90 grams of 2,4,6-trifluoro-3,5-dichlorobenzoic acid, 540 grams of water, 33 grams of magnesium oxide, and 0.9 grams of 10% wet palladium-carbon to a 1-liter pressure-resistant reactor. Replace the gas with nitrogen 3 times, and then replace the gas with hydrogen 5 times. Use hydrogen to control the internal pressure of the kettle to 0.8-0.9 MPa, turn on the stirring, increase the temperature to 80-85°C for 10 hours, and stop the reaction. The reaction system is lowered to room temperature, the pressure in the kettle is removed, the reaction liquid is filtered, and the filtrate is adjusted to pH 1-2 with 20% hydrobromic acid solution, filtered, and the filter cake is rinsed and dried to obtain 2,4,6-Trifluorobenzoic acid 62.95 grams, the yield is 97.3%, and the purity is 99.1%.

Structure and conformation

In the title compound, C7H3F3O2, the C—C—C angles in the ring are greater than 120° for F-bonded C atoms [123.69 (13), 123.88 (12) and 123.66 (12)°]. In the crystal, inter-molecular O—H—O hydrogen bonds between carboxyl groups give rise to the formation of a centrosymmetric dimer, while dispersive F—O contacts [2.8849 (16) Å] connect the dimers into infinite strands along the a axis.

2,4,6-Trifluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,6-Trifluorobenzoic acid Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
CAS Organic Company
Tel
--
Fax
--
Email
Sales@casorganic.com
Country
Ukraine
ProdList
5026
Advantage
34
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View Lastest Price from 2,4,6-Trifluorobenzoic acid manufacturers

Speranza Chemical Co., Ltd.
Product
2,4,6-Trifluorobenzoic acid 28314-80-9
Price
US $20.00/KG
Min. Order
1KG
Purity
0.98
Supply Ability
200tons/ year
Release date
2020-03-11
Zibo Hangyu Biotechnology Development Co., Ltd
Product
2,4,6-Trifluorobenzoic acid 28314-80-9
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
2,4,6-Trifluorobenzoic acid 28314-80-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

28314-80-9, 2,4,6-Trifluorobenzoic acidRelated Search:


  • BUTTPARK 44\01-13
  • 2,4,6-TRIFLUOROBENZOIC ACID
  • 2,4,6-Trifluorobenzo
  • 2,4,6-trifluorobenzoic acid derivatives
  • 2,4,6-TRIFLUOROBENZIOC ACID
  • 2,4,6-Trilfuorobenzoic acid
  • 2,4,6-TRIFLUOROBENZOIC ACID THE DERIVATIVES
  • 2,4,6-Trifluorobenzoic
  • 2,4,6-Trifluorobenzoic acid 98%
  • 2,4,6-Trifluorobenzoicacid98%
  • 2,4,6-Trifluorobenzoic acid and the derivatives
  • TIMTEC-BB SBB006688
  • RARECHEM AL BO 0448
  • 2,4,6-TRIFLUOROBEN
  • 2,4,6-TRIFLUOROBENZOIC ACID THE DERI
  • 2,4,6-Trifluorobenzoic Acid, 97+%
  • 2,4,6-triflouorobnzoic acid
  • 2,4,6-TrifL
  • Benzoic acid, 2,4,6-trifluoro-
  • Lamidipan Impurity 1
  • Lasmiditan Impurity
  • 28314-80-9
  • 314-80-9
  • C7H2F3O2R
  • ARYL ACID
  • Organic Building Blocks
  • C7
  • Carboxylic Acids
  • Carbonyl Compounds
  • Building Blocks
  • Pharm intermediate
  • Fluorine series
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Benzene series
  • Benzoic acid
  • Heterocyclic Compounds
  • Miscellaneous
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids