Chemical properties Application
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Prallethrin

Chemical properties Application
Product Name
Prallethrin
CAS No.
23031-36-9
Chemical Name
Prallethrin
Synonyms
ETOC;s4068;Pralle;ETOC(R);s-4068sf;NYLAR(R);ai3-29750;PRALLETHRIN;S-4068 forte;Prallethrin 0
CBNumber
CB4471390
Molecular Formula
C19H24O3
Formula Weight
300.39
MOL File
23031-36-9.mol
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Prallethrin Property

Melting point:
25°C
Boiling point:
381.62°C (rough estimate)
Density 
d420 1.03
vapor pressure 
﹤4.3×10-5 Pa (23.1 °C)
refractive index 
1.4200 (estimate)
Flash point:
139 °C
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly)
Water Solubility 
8 mg l-1 (25 °C)
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
23031-36-9(CAS DataBase Reference)
EPA Substance Registry System
Prallethrin (23031-36-9)
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Safety

Hazard Codes 
T,N
Risk Statements 
22-23-50/53
Safety Statements 
45-60-61
RIDADR 
UN2811 6.1/PG 2
WGK Germany 
3
HS Code 
29162090
Hazardous Substances Data
23031-36-9(Hazardous Substances Data)
Toxicity
mouse,LD50,oral,190mg/kg (190mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H331Toxic if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32917
Product name
Prallethrin
Purity
PESTANAL
Packaging
100mg
Price
$233
Updated
2024/03/01
Cayman Chemical
Product number
25813
Product name
Prallethrin
Purity
≥95%
Packaging
50mg
Price
$35
Updated
2021/12/16
Cayman Chemical
Product number
25813
Product name
Prallethrin
Purity
≥95%
Packaging
100mg
Price
$67
Updated
2021/12/16
Cayman Chemical
Product number
25813
Product name
Prallethrin
Purity
≥95%
Packaging
250mg
Price
$140
Updated
2021/12/16
TRC
Product number
P700600
Product name
Prallethrin(Mixtureofdiastereomers)
Packaging
250mg
Price
$105
Updated
2021/12/16
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Prallethrin Chemical Properties,Usage,Production

Chemical properties

The original medicine is an oil like liquid. At b.p.>313.5℃ , the relative density is 1.03. It is easy to dissolve in methanol and hexane. The solubility is >50% at normal temperature, The solubility in the water at 25 C is 8.03mg/L, The distribution coefficient is 30800.

Application

The product characteristics of fenvalerate are the same as those of fenpropathrin with strong contact toxicity. The knockdown and killing performance is 4 times higher than that of the right-handed trans pyrethrin, and has a prominent driving effect on cockroaches. It is mainly used for processing mosquito repellent incense, electric mosquito repellent incense, liquid mosquito repellent incense and spray to control household pests such as housefly, mosquito, louse, cockroach etc. The recommended amount of use is as follows: (with effective ingredients) mosquito repellent incense: The electric heat mosquito incense containing 0.05% of the product: Containing 10mg/ tablets of this product to control the temperature of the electric heater center at 125-135℃. Liquid mosquito repellent incense: containing 0.66% of this product, plus proper stabilizer; Sustained-release agent; Aerosols: 0.05 0.2% of this product with appropriate amount of lethal agent, synergist and emulsifier.

Chemical Properties

solid

Uses

Prallethrin is used for the control of insects in domestic and public health situations.

Uses

Prallethrin ia a synthetic pyrethroid; propynyl analog of allethrin. Prallethrin is used as an insecticide.

Definition

ChEBI: Prallethrin is a member of cyclopropanes and a terminal acetylenic compound. It has a role as a pyrethroid ester insecticide and an agrochemical. It is functionally related to a chrysanthemic acid.

Hazard

A poison by ingestion and inhalation. Low toxicity by skin contact.

Pharmacology

Prallethrin is a propynyl analog of allethrin, with 2-methyl-4-oxo-3-(prop-2-ynyl)-cyclopent-2-enyl as the secondary alcohol moiety that has been introduced against public health pests (113–115). The ester of the (S)-alcohol with (1R)-trans,cis-chrysanthemic acid resolved partially is commercialized on the strength of the assessment of insecticidal action of individual stereoisomers (116). Compared with d-allethrin, it is approximately four, six, and five times more effective on Musca domestica (for killing), Blattella germanica (for killing), and Culex pipiens pallens (for knockdown), respectively (43). A lower level of resistance to prallethrin than to phenoxybenzyl pyrethroids was demonstrated in a kdr-resistant housefly strain (116).

Safety Profile

A poison by ingestion and inhalation. Low toxicity by skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.

Metabolic pathway

Prallethrin is stable under normal room temperature storage conditions for up to 36 months. It is labile to alkali at the ester linkage, forming 2 and 3 (Scheme 1). Analogy with the allethrins (from which it differs only in the degree of unsaturation in the side chain - propyne rather than propene) would suggest that the compound is very photolabile.

Degradation

The metabolism of prallethrin was studied following single oral administration and subcutaneous injection of the cis- and trans-isomers to rats at two dose levels and after repeated dosing. The compound was labelled in the alcohol moiety (inferred from the results) (PSD, 1995).
Absorption was rapid with maximum tissue residues being attained 3 hours after the dosing of each isomer. Biphasic clearance of radioactivity then occurred with half-lives of 3 and 14-23 hours (cis-isomer) and 3-5 and 7-35 hours (trans-isomer). Urinary excretion accounted for 13-32% (cis-isomer) and 45-62% (trans-isomer) of the dose with most of the balance in the faeces. Less than 0.1% was exhaled as 14CO2 . Residues in tissues were very low (0.3% of the dose at 7 days). Metabolism and disposition were independent of dose and dose route but residues in tissues were somewhat higher for the cis-isomer.
Twenty-one metabolites were identified (taking account of stereochemistry and conjugates). The major pathways of metabolism involved oxidation at a methyl group of the isobutenyl group in the acid moiety (giving 4 and 5), at the C1 and C2 positions of the propynyl group in the alcohol moiety (giving 6 and 9) and dihydroxylation (to 7 and 8). The resulting hydroxy derivatives were conjugated with glucuronic acid and sulfate.
Hydrolysis of prallethrin also occurred to afford the acid 2 (presumed) and the alcohol 3. Hydrolysis of the hydroxylated prallethrins and further oxidation of 3 afforded 10 and 11. Further oxidation of 10 to the cyclic tertiary alcohol (12) was observed.
When bluegill sunfish were exposed to a l4C-labelled (acid and alcohol groups) prallethrin isomer (1Rtrans), more than 50% of the biliary radioactivity recovered from the gall bladder was observed as one ester metabolite. This was identified as the taurine conjugate of carboxylic acid metabolite 5 (Oshima et al., 1992).

Prallethrin Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate Methylglyoxal Ethanol N,N-Dimethylformamide PROPARGYL BENZENESULFONATE Sodium ethoxide Acetylacetone 6-Heptynoic acid 1-Hexyne Ethyl acetate CHAMAZULEN

Preparation Products

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Prallethrin Suppliers

Canada 2 China 100 Europe 1 France 2 Germany 2 India 7 Italy 1 South Korea 1 Switzerland 1 United Kingdom 2 United States 15 Global 134
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
ProdList
94838
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ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
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China
ProdList
2572
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Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
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50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
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BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
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11726
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UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
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+86 (21) 5895-8628
Email
SALES@UHNSHANGHAI.COM
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China
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The future of Shanghai Industrial Co., Ltd.
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021-61552785
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021-55660885
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sales@shshiji.com
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China
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Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
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China
ProdList
3750
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Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
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422131432@qq.com
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China
ProdList
9986
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TianJin Alta Scientific Co., Ltd.
Tel
022-65378550-8551
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+86-022-2532-9655
Email
contact@altascientific.com
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China
ProdList
2773
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View Lastest Price from Prallethrin manufacturers

Hebei Duling International Trade Co. LTD
Product
Prallethrin 23031-36-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-04-25
Hubei Langyou International Trading Co., Ltd
Product
Prallethrin 23031-36-9
Price
US $300.00/KG
Min. Order
20KG
Purity
93%
Supply Ability
20000 tons
Release date
2021-08-19
Hebei Yanxi Chemical Co., Ltd.
Product
Prallethrin 23031-36-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-09-18

23031-36-9, PrallethrinRelated Search:

Allethrin N,N-Dimethylacetamide Dimethyl carbonate ETHANE chlorempenthrin S-Bioallethrin N,N-Dimethylallylamine Esbiothrin Imiprothrin N,N-Dimethylformamide Dimethyl sulfoxide Dimethyl phthalate Dimethyl sulfate Cyclopropane Poly(dimethylsiloxane) Dimethyl fumarate Dacthal Dimethyl ether

  • s-4068sf
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  • (RS)-2-Methyl-4-oxo-3-prop-2-ynylcyclopent-2-enyl (1RS,3RS:1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
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  • 2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid 2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl ester
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  • S-4068 forte
  • 2,2-DiMethyl-3-(2-Methyl-1-propen-1-yl)cyclopropanecarboxylic Acid 2-Methyl-4-oxo-3-(2-propyn-1-yl)-2-cyclopenten-1-yl Ester
  • Acetylene C PerMethrin
  • trans-(±)-4-Hydroxy- 3-Methyl-2-(2-propynyl)-2-cyclopenten-1-one 2,2-DiMethyl-3-(2-Methylpropenyl) cyclopropanecarboxylate, (8CI)
  • Prallethrin 10mg [23031-36-9]
  • 2-Methyl-4-oxo-3-(prop-2-yn-1-yl)cyclopent-2-en-1-yl 2,2-diMethyl-3-(2-Methylprop-1-en-1-yl)cyclopropanecarboxylate
  • Prallethrin (Mixture of diastereoMers)
  • (S)-2-METHYL-4-OXO-3-(2-PROPYNYL)-CYCLOPENT-1-YL (1R)-CIS-TRANS-CHRYSANTHEMATE
  • (S)-2-METHYL-4-OXO-3-PROP-2-YNYLCYCLOPENT-1-YL(1R)-CIS,TRANS-2,2-DIMETHYL-3-(2-METHYLPROP-1-ENYL)-CYCLOPROPANECARBOXYLATE
  • PRALLETHRIN
  • NYLAR(R)
  • (RS)-2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl(1RS)-cis,trans-chrysanthemate
  • Prallethrin 0
  • (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)-1-cyclopropanecarboxylic acid [(1R)-2-methyl-4-oxo-3-prop-2-ynyl-1-cyclopent-2-enyl] ester
  • D-Trans-Prallethrin
  • 2-Methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
  • Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl ester
  • prallethrin (bsi,draft e-iso9, prallethrine (draft f-iso)etoc
  • PRALLETHRIN,RICH-D-TRANS
  • 2,2-Dimethyl-3-(2-methylprop-1-enyl)-cyclopropanecarboxylate
  • 2-Methyl-4-oxo-3-(prop-2-ynyl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
  • ETOC(R)
  • ETOC
  • CYCLOPROPANECARBOXYLIC ACID, 2,2-DIMETHYL-3-(2-METHYL-1-PROPENYL)-(1S)-2-METHYL-4-OXO-3-(2-PROPENYL)-2-CYCLOPENTEN-1-YL ESTER, (1R)
  • prallethrin ETOC 2-methyl-4-oxo-3-(prop-2-ynyl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
  • 2,2-dimethyl-3-(2-methylpropenyl)-,esterwith4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-oCyclopropanecarboxylicacid
  • 2-dimethyl-3-(2-methylpropenyl)-esterwith4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-onecyclopropanecarboxylicaci
  • 2-Methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl(1R)-cis,trans-chrysanthemate
  • ai3-29750
  • d,d-t80-prallethrin
  • s4068
  • Prallethrin @100 μg/mL in Methanol
  • Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 2-methyl-4-oxo-3-(2-propyn-1-yl)-2-cyclopenten-1-yl ester
  • Prallethrin(Mixture of diastereom)
  • 23031-36-9
  • Agro-Products
  • INSECTICIDE