Bispyrithione
- Product Name
- Bispyrithione
- CAS No.
- 3696-28-4
- Chemical Name
- Bispyrithione
- Synonyms
- OMDS;osy20;omadineds;NSC 84740;NSC 677437;NSC 241716;ipyrithione;dipyrithione;BISPYRITHIONE;omadinedisulfide
- CBNumber
- CB4500917
- Molecular Formula
- C10H8N2O2S2
- Formula Weight
- 252.31
- MOL File
- 3696-28-4.mol
Bispyrithione Property
- Melting point:
- 200.5°C (rough estimate)
- Boiling point:
- 582.8±25.0 °C(Predicted)
- Density
- 1.4423 (rough estimate)
- refractive index
- 1.5650 (estimate)
- solubility
- Methanol (Slightly), Water (Slightly, Heated, Sonicated)
- pka
- -0.77±0.10(Predicted)
- form
- solid
- color
- Gray or off-white paste
- PH
- 5.0-7.0(25°C,1%soln.)
- Stability:
- Hygroscopic
- EPA Substance Registry System
- Dipyrithione (3696-28-4)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D494253
- Product name
- 2,2''-Dithiobis(pyridine-N-oxide)
- Packaging
- 2mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- D494253
- Product name
- 2,2''-Dithiobis(pyridine-N-oxide)
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FD165252
- Product name
- 2,2'-Dithiobis(pyridine-N-oxide) - 80%
- Packaging
- 100g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- OR912173
- Product name
- 2,2'-Dithiobis(pyridine-N-oxide)
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- J10433
- Product name
- 2,2'-Dithiobis(pyridine-N-oxide)
- Packaging
- 5mg
- Price
- $19.8
- Updated
- 2021/12/16
Bispyrithione Chemical Properties,Usage,Production
Description
Bispyrithione is a pyrithione derivate used as bactericide and fungicide. The drug was marketed under the name Crimanex in the form of shampoo for the treatment of dandruff, however it is no longer available on the manufacturer website (Drossa Pharm . It is currently used as a pesticide.
Chemical Properties
beige to slightly grey powder and chunks
Uses
Bispyrithione can be used as an antibacterial; antifungal.
Application
Bispyrithione is a new antidandruff agent behind zinc pyrithione. It has similar chemical structure to zinc pyrithione, thus performs the same bactericidal property, with unique bactericidal actions, especially to mycetes, mild fungus and microzymes. It also can effectively disinfect oval bacil, candia albicans and other mycetes, while normal antimicrobials can't. It is not sensitive to metal ion and dissolves in water more easily than zinc pyrithione, which improves the compatibility and leads to best bactericidal effect. In 2-in-1 shampoo, it doesn't affect the pearly effect but enhance color stability.
Definition
ChEBI: Dipyrithione is a pyridinium ion.
Synthesis
1, drop into successively the 600g2-chloropyridine in the 5000ml four-hole boiling flask, 100g maleic and acid anhydrides, 600g hydrogen peroxide (35%) are opened to stir and are warmed up to 60 ℃ of successive reactions 12 hours, make 2-chloropyridine-N-oxide water solution.
2, the 2-chloropyridine that uses the 4000g2-methyl chloride to divide four extractions to make-N-oxide water solution merges extraction phase, and condensing crystal makes sterling 2-chloropyridine-N-oxide compound.
3, the 2-chloropyridine that purification is obtained-N-oxide compound, 430g sodium sulphite, the 2000g high purity water, drop into successively in the 5000ml four-hole boiling flask, open and stir, be warming up to 70 ℃, along with the carrying out of reaction added a part of yellow soda ash in good time, the PH of adjustment system is stabilized in 9～10, and reaction finishes 70 ℃ of insulations 2 hours, and insulation finishes to cool.Make the pyrithione sodium water solution.
4, use an amount of dilute sulphuric acid to adjust the PH to 2 of pyrithione sodium water solution system, separate out a large amount of white crystals.Filtrated stock cleans solid, namely gets pyrithione.
5, the pyrithione that the reaction of upper step is obtained, the 1000g ultrapure water drops in the plastic cup, the unlatching dispersed with stirring is even, then slowly splash into 220g hydrogen peroxide (35%), reaction is 1 hour about 50 ℃, make finished product Bispyrithione 497g (99.72%, five step of content overall yield of reaction: 74.6%).
Bispyrithione Preparation Products And Raw materials
Raw materials
Preparation Products
Bispyrithione Suppliers
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- 0510-83593312 13665125081
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- 021-50795055
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- China
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- 400-188-0725 +86 21 34310725 13611771617
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- +86 21 34311076
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- Please Send Email 18652950785
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- 025-87193546
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- +86-21-61629029
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- 0371-13526885213 15637198702
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- 0371-63709726
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View Lastest Price from Bispyrithione manufacturers
- Product
- Bispyrithione 3696-28-4
- Price
- US $0.00/Kg/Drum
- Min. Order
- 25Kg/Bag
- Purity
- 0.3
- Supply Ability
- 20tons
- Release date
- 2021-12-28
- Product
- Bispyrithione 3696-28-4
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-19
- Product
- Bispyrithione 3696-28-4
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000tons
- Release date
- 2023-06-19