Dimethyl 2,4-pyridinedicarboxylate
- Product Name
- Dimethyl 2,4-pyridinedicarboxylate
- CAS No.
- 25658-36-0
- Chemical Name
- Dimethyl 2,4-pyridinedicarboxylate
- Synonyms
- Nsc78960;Dimethyl 2,4-pyridinedicarboxylate;diMethyl pyridine-2,4-dicarboxylate;2,4-DIMETHYL PYRIDINE-2,4-DICARBOXYLATE;2,4-Pyridinedicarboxylic acid dimethyl ester;2,4-pyridine dicarboxylic acid 2,4-diMethyl ester;2,4-PYRIDINEDICARBOXYLIC ACID,DIMETHYL ESTER(6Cl,7Cl,8Cl,9Cl);Dimethyl 2,4-Pyridinedicarboxylate Pyridine-2,4-Dicarboxylic Acid Dimethyl Ester
- CBNumber
- CB42263641
- Molecular Formula
- C9H9NO4
- Formula Weight
- 195.17
- MOL File
- 25658-36-0.mol
Dimethyl 2,4-pyridinedicarboxylate Property
- Melting point:
- 252-253 °C(Solv: water (7732-18-5))
- Boiling point:
- 302.5±22.0 °C(Predicted)
- Density
- 1.231±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -0.96±0.10(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D482445
- Product name
- DimethylPyridine-2,4-dicarboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3273AL
- Product name
- Dimethylpyridine-2,4-dicarboxylate
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 118084
- Product name
- Dimethyl pyridine-2,4-dicarboxylate
- Packaging
- 1g
- Price
- $536
- Updated
- 2021/12/16
- Product number
- 4H23-1-8U
- Product name
- Dimethyl pyridine-2,4-dicarboxylate
- Packaging
- 1g
- Price
- $560
- Updated
- 2021/12/16
- Product number
- CHM0004164
- Product name
- PYRIDINE-2,4-DICARBOXYLIC ACID DIMETHYL ESTER
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $945.95
- Updated
- 2021/12/16
Dimethyl 2,4-pyridinedicarboxylate Chemical Properties,Usage,Production
Synthesis
67-56-1
499-80-9
25658-36-0
Phosphorus pentachloride (PCl5, 39 g, 0.186 mol, 3 eq.) and 2,4-pyridinedicarboxylic acid (11.5 g, 6.2 x 10^-2 mol) were added to a 500 mL round bottom flask. The mixture was stirred at room temperature for 45 minutes and the mixture was observed to transform into a green liquid. Subsequently, the reaction mixture was diluted with dichloromethane (80 mL) and methanol (20 mL) was added slowly. The reaction mixture was poured into water (300 mL) containing sodium bicarbonate (NaHCO3, 60 g), the aqueous phase was extracted with dichloromethane (4 x 50 mL) and the combined organic phases were washed with 1 M sodium carbonate (Na2CO3, 2 x 50 mL). The crude product was purified by fast column chromatography (eluent: ethyl acetate/cyclohexane, 75:25). A solid product of 11.71 g was obtained in 96% yield. The product was stored at room temperature.1H NMR (200 MHz, CDCl3): δ 4.03 (s, 3H, -OCH3), 4.09 (s, 3H, -OCH3), 8.07 (dd, J = 6 Hz, 1H, H-3), 8.68 (s, 1H, H-5), 8.91 (d, 1H, H-2).13C NMR (75 MHz. CDCl3): δ 53.28 (-OCH3), 124.49 (C-5), 126.29 (C-3), 138.64 (C-4), 149.06 (C-6), 150.92 (C-2), 162.45 (C=O), 164.96 (C=O).
References
[1] Patent: US9266902, 2016, B2. Location in patent: Page/Page column 12
[2] Chemistry - An Asian Journal, 2018, vol. 13, # 19, p. 2854 - 2867
[3] Bulletin of the Chemical Society of Japan, 1985, vol. 58, # 4, p. 1331 - 1332
[4] Journal of the American Chemical Society, 2003, vol. 125, # 1, p. 296 - 304
[5] Patent: WO2010/43866, 2010, A2. Location in patent: Page/Page column 77-78
Dimethyl 2,4-pyridinedicarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dimethyl 2,4-pyridinedicarboxylate manufacturers
- Product
- Dimethyl 2,4-pyridinedicarboxylate 25658-36-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09