PIMARIC ACID

Product Name: PIMARIC ACID
CAS No.: 127-27-5
Chemical Name: PIMARIC ACID
Synonyms: Pimaric;NSC 2956;PIMARIC ACID;Pimaric Acid (>DextropiMaric Acid;Δ8(14)-PiMaric Acid;Pimaric acid (PiMA);Pimaric Acid (> 75%);Hexazinone Impurity 27;8(14),15-PiMaradien-18-oic Acid
CBNumber: CB4506393
Molecular Formula: C20H30O2
Formula Weight: 302.45
MOL File: 127-27-5.mol

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PIMARIC ACID Property

Melting point:: 217-219°
alpha: D18 +74.7° (c = 0.4 in chloroform); D20 +87.3° (in chloroform)
Boiling point:: bp18 282°
Density: 1.0434 (rough estimate)
refractive index: 1.4800 (estimate)
storage temp.: Store at -20°C
solubility: DMSO: soluble,Water: soluble
pka: 4.68±0.60(Predicted)
form: Solid
color: White to off-white
LogP: 6.731 (est)
EPA Substance Registry System: Pimaric acid (127-27-5)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26062
Product name: Pimaric Acid
Packaging: 500μg
Price: $68
Updated: 2022/04/27

Cayman Chemical

Product number: 26062
Product name: Pimaric Acid
Packaging: 5mg
Price: $269
Updated: 2022/04/27

Cayman Chemical

Product number: 26062
Product name: Pimaric Acid
Packaging: 1mg
Price: $122
Updated: 2022/04/27

Usbiological

Product number: 286933
Product name: Pimaric acid
Packaging: 1mg
Price: $582
Updated: 2021/12/16

TRC

Product number: P445100
Product name: PimaricAcid(>75%)
Packaging: 10mg
Price: $1540
Updated: 2021/12/16

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PIMARIC ACID Chemical Properties,Usage,Production

Description

Pimaric acid is a resin acid that has been found in A. cordata and various pines. It reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) in a concentration-dependent manner when used at concentrations ranging from 5 to 20 μM. Pimaric acid (10-20 μM) reduces nuclear expression and binding of the transcription factors NF-κB and AP-1 to the MMP-9 promoter in HASMCs. Pimaric acid also reduces TNF-α-induced HASMC migration to control levels when used at a concentration of 20 μg/ml.

Uses

A novel activators of large-conductance Ca2+-activated K+ channel α-subunit.

Definition

ChEBI: (+)-Pimaric acid is a diterpenoid.

PIMARIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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PIMARIC ACID Suppliers

Canada 1 China 55 Germany 1 India 1 United Kingdom 1 United States 9 USA 1 Global 69

ALB Technology Limited

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EMMX Biotechnology LLC

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Aladdin Scientific

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TargetMol Chemicals Inc.

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Alfa Chemistry

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MedChemExpress

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Cayman Chemical Company

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3B Scientific Corporation

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MP Biomedicals, Inc.

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View Lastest Price from PIMARIC ACID manufacturers

Career Henan Chemical Co

Product: PIMARIC ACID 127-27-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 20 tons
Release date: 2019-12-25

127-27-5, PIMARIC ACIDRelated Search:

Sodium tungstate 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Cyperone beta-Sitosterol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether MOSLOFLAVONE Hydroxyecdysone beta-Eudesmol hydroxygenkwanin alpha-Terpineol cis-1,2,3,6-Tetrahydrophthalic anhydride sandaracopimaric acid PIMARIC ACID (CIS)-8-METHYLNON-6-ENOIC ACID

(1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-triMethyl-1-phenanthrenecarboxylic Acid

13α-Methyl-13-vinylpodocarp-8(14)-en-15-oic acid

PIMARIC ACID

1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahyd

7-trimethyl-,[1theta-(1alpha,4abeta,4balpha,7beta,10aalpha)]-ro-4a

13-alpha-methyl-13-vinylpodocarp-8(14)-en-15-oic acid

1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,4bS,7S,10aR)-

8(14),15-PiMaradien-18-oic Acid

DextropiMaric Acid

NSC 2956

PiMara-8(14),15-dien-19-oic Acid

Δ8(14)-PiMaric Acid

Pimaric Acid (Contains 10-25% Sandaracopimaric Acid)

Pimaric Acid (&gt

Pimaric Acid (> 75%)

Pimaric

Hexazinone Impurity 27

Pimaric acid (PiMA)

127-27-5

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