1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Product Name: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
CAS No.: 7226-23-5
Chemical Name: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
Synonyms: DMPU;1,3-Dimethyltetrahydropyrimidin-2(1H)-one;1,3-Dimethyl-1,3-diazinan-2-one;1,3-DIMETHYLTETRAHYDRO-2-PYRIMIDINONE;tetrahydro-1,3-dimethyl-2(1h)pyrimidine;Lycii Cortex;DMPU(solvent);mmHg： 7.5（50℃）;Cortex Lycii P.E.;Tedizolid Impurity 69
CBNumber: CB4675240
Molecular Formula: C6H12N2O
Formula Weight: 128.17
MOL File: 7226-23-5.mol

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1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone Property

Melting point:: -20 °C
Boiling point:: 146 °C44 mm Hg(lit.)
Density: 1.06 g/mL at 25 °C(lit.)
vapor pressure: 0.5 hPa (57 °C)
refractive index: n20/D 1.488(lit.)
Flash point:: 121 °C
storage temp.: Store below +30°C.
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Liquid
pka: -0.65±0.20(Predicted)
color: Clear colorless to slightly yellow
PH: 11 (100g/l, H2O, 20℃)
explosive limit: 1.6-9.3%(V)
Water Solubility: soluble
Sensitive: Hygroscopic
BRN: 110562
Dielectric constant: 36.119999999999997
Stability:: Hygroscopic
InChIKey: GUVUOGQBMYCBQP-UHFFFAOYSA-N
LogP: 0.05 at 25℃
CAS DataBase Reference: 7226-23-5(CAS DataBase Reference)
EPA Substance Registry System: 2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl- (7226-23-5)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36-43-62-41
Safety Statements: 23-26-36/37/39-45
WGK Germany: 2
RTECS: UW7582500
F: 3-10
Autoignition Temperature: 255 °C
TSCA: Yes
HS Code: 29335995
Toxicity: LD50 orally in Rabbit: 1770 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.18214
Product name: 1,3-Dimethyltetrahydro-2(1H)-pyrimidinone
Purity: for synthesis
Packaging: 100mL
Price: $84
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.18214
Product name: 1,3-Dimethyltetrahydro-2(1H)-pyrimidinone
Purity: for synthesis
Packaging: 500mL
Price: $221
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.18214
Product name: 1,3-Dimethyltetrahydro-2(1H)-pyrimidinone
Purity: for synthesis
Packaging: 25kg
Price: $4890
Updated: 2025/07/31

Sigma-Aldrich

Product number: 251569
Product name: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
Purity: 98%
Packaging: 25g
Price: $40.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: 251569
Product name: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
Purity: 98%
Packaging: 100g
Price: $86.9
Updated: 2025/07/31

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1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone Chemical Properties,Usage,Production

Chemical Properties

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is clear colorless to slightly yellowish liquid

Uses

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is a versatile organic solvent in and less toxic than HMPA. It is mainly applied in the synthesis of pharmaceuticals and agrochemicals. DMPU is also used in the electronics industry.

Uses

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is a versatile solvent used in the N-alkylation of chiral and O-alkylation of aldoses. It is involved in the preparation of poly(aryl ethers). It is a cyclic urea and used as a polar aprotic organic solvent. Further, it reacts with trifluoro-methanesulfonic acid anhydride to prepare 2,2'-oxy-bis(1,3-dimethyl-tetrahydropyrimidinium) bis(trifluoromethanesulfonate).

Uses

Versatile solvent employed in N-alkylation of chiral, primary amines, O-alkylation of aldoses, and in the synthesis of poly(aryl ethers).

Flammability and Explosibility

Non flammable

Synthesis

124-38-9

142-28-9

74-89-5

7226-23-5

96690-06-1

The general procedure for the synthesis of N,N-dimethylpropenyl urea and compounds (CAS:96690-06-1) from carbon dioxide, 1,3-dichloropropane and monomethylamine was as follows: 1.24 g of aqueous 1,3-dichloropropane and 5.15 g of a 40% aqueous solution of methylamine were added to a pressure vessel made of 20 mL of SUS316. At a pressure of about 0.5 MPa, 1.95 g of carbon dioxide gas was passed into the vessel. Subsequently, the reaction mixture was reacted at a constant temperature at 120°C for 2 hours. At the end of the reaction, 3-methyl-1,3-oxazin-2-one was obtained in 15% yield, as well as 1,3-dimethyltetrahydropyrimidin-2(1H)-one in 64% yield.

References

[1] Patent: US2005/154200, 2005, A1. Location in patent: Page/Page column 4

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone Preparation Products And Raw materials

Raw materials

Benzyltriethylammonium chloride p-Toluenesulfonic acid monohydrate Potassium carbonate 1,4-Dioxane Propyleneurea Dichloromethane Dimethyl sulfate

Preparation Products

2-MORPHOLINONICOTINALDEHYDE 2-Chloro-3-pyridinecarboxaldehyde

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1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone Suppliers

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View Lastest Price from 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone manufacturers

.GZ HONESTCHEM CO.,LTD

Product: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone 7226-23-5
Price: US $1.00/g
Min. Order: 300g
Purity: 99.8%
Supply Ability: 20 TONS
Release date: 2025-10-20

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone 7226-23-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-12

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone 7226-23-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

7226-23-5, 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinoneRelated Search:

Dimethicone Dimethyl fumarate Dimethyl sulfoxide Dimethyl sebacate Dimethyl sulfone ETHANE Dimethyl carbonate CHLORPROPAMIDE 2,2-Dimethyl-1,3-propanediol Dimethyl phthalate CHLORODIMETHYLVINYLSILANE Dimethyl ether POLY(N-ISOPROPYL ACRYLAMIDE) N,N-Dimethylaniline N-Methylolacrylamide Poly(dimethylsiloxane) N,N-Dimethylformamide N,N-Dimethylacetamide

1,3-dimethyl-perhydro-2-pyrimidinone

1,3-dimethyl-tetrahydro-pyrimidin-2-one

n,n’-dimethyltrimethyleneurea

tetrahydro-1,3-dimethyl-2(1h)pyrimidine

tetrahydro-1,3-dimethyl-2(1h)-pyrimidinon

1,3-Dimethyl-2-oxohexahydropyrimidine

1,3-Dimethyltetrahydropyrimidin-2(1H)-one

DMPUN,N'-DiMethylpropyleneurea

1,3-DiMethyl-3,4,5,6-tetrahydro-2(1H)-pyriMidinone, 97%, pure

1,3-DiMethyl-3,4,5,6-tetrahydro-2(1H)-pyriMidinone, 97% 100ML

1,3-DiMethyl-3,4,5,6-tetrahydro-2(1H)-pyriMidinone, 97% 500ML

1,3-DIMETHYLTETRAHYDRO-2(1H)-PYRIMIDINON

1,3-DiMethyl-3,4,5,6-tetrahydro-2(1H)-pyriMidinone 98%

1,3-DiMethyl-3,4,5,6-tetrahydro-2(1H)-pyriMidinone absolute, over Molecular sieve (H2O <=0.03%), >=99.0% (GC)

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1<i>H</i>)-pyrimidinone (DMPU)

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone≥ 99% (GC)

1,3-Dimethyltetrahydro-2(1H)-pyrimidinone for synthesis

LABOTEST-BB LT00848352

DMPU

DIMETHYLPROPYLENE UREA

DIMETHYL(1,3-)-3,4,5,6-TETRAHYDRO-2H-PYRIMIDONE

1,3-DIMETHYLTETRAHYDRO-2-PYRIMIDINONE

1,3-DIMETHYL-PROPYLENEUREA

1,3-DIMETHYL-2-OXOHEXAHYDROPYIRIMIDINE

1,3-Dimethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one

tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one

N,N'-Dimethyl-N,N'-trimethyleneurea (DMPU)

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidione

2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-

N,N'-Dimethylpropylenharnstoff

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU)

1,3-DIMETHYL-3,4,5,6-TETRAHYDRO-2(1H)-PYRIMIDONE

N,N-Dimethyl Propylene urea(DMPU)

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 98+%

1,3-Dimethyl-2-oxohexahydropyrimidine, N,Nμ-Dimethylpropylene urea, DMPU

1,3-Dimethyl-1,3-diazinan-2-one

3,4,5,6-Tetrahydro-1,3-dimethyl-2(1H)-pyrimidinone

3,4,5,6-Tetrahydro-1,3-dimethylpyrimidin-2(1H)-one

DMPU(solvent)

N,N'-DIMETHYL-N,N'-TRIMETHYLENEUREA

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone,97%

1,3-DIMETHYL-3,4,5,6-TETRAHYDRO-2(1H)-PY RIMIDINONE ABS.

N,N-Dimethyl Propionyl urea

1,3-Dimethyl-3,4,5,6- tetrahydro-2-pyrimidinone

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone ,99%

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone ,99.95%

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone,1,3-Dimethyl-2-oxohexahydropyrimidine, N,N′-Dimethylpropylene urea, DMPU

Cortex Lycii P.E.

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, pure, 97%

3-DiMethyl-propyleneurea

1,3-DIMETHYL-3,4,5,6-TETRAHYDRO-2(1H)-PYRIMIDINONE

Lycii Cortex

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone 7226-23-5

1,3-Dimethyltetrahydro-2(1H)-pyrimidinone

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone&gt

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinonel

Tedizolid Impurity 69

-3,4,5,6-tetrahydro-2(1H)-pyrimidinone