1-Indanone-6-carboxylic acid

Product Name: 1-Indanone-6-carboxylic acid
CAS No.: 60031-08-5
Chemical Name: 1-Indanone-6-carboxylic acid
Synonyms: 6-CARBOXY-1-INDANONE;6-CARBOXYLIC ACID 1-INDANONE;1-INDANONE-6-CARBOXYLIC ACID;3-OXOINDANE-5-CARBOXYLIC ACID;3-OXO-INDAN-5-CARBOXYLIC ACID;3-oxo-1,2-dihydroindene-5-carboxylic Acid;2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID;3-oxo-2,3-dihydro-1H-indene-5-carboxylic acid;1H-Indene-5-carboxylic acid, 2,3-dihydro-3-oxo-;JR-8361, 2,3-Dihydro-3-oxo-1H-indene-5-carboxylic acid, 97%
CBNumber: CB4684307
Molecular Formula: C10H8O3
Formula Weight: 176.17
MOL File: 60031-08-5.mol

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1-Indanone-6-carboxylic acid Property

Melting point:: 256-260 °C
Boiling point:: 375.2±31.0 °C(Predicted)
Density: 1.381±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 3.99±0.20(Predicted)
Appearance: White to off-white Solid
CAS DataBase Reference: 60031-08-5(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 25-36/37/38
Safety Statements: 26-36/37/39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2918300090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: I655748
Product name: 1-Indanone-6-carboxylicAcid
Packaging: 25g
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0967081
Product name: 2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 1G
Price: $1030.84
Updated: 2021/12/16

AK Scientific

Product number: W7273
Product name: 1-Indanone-6-carboxylicacid
Packaging: 10g
Price: $1747
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0967081
Product name: 2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5G
Price: $4244.63
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0967081
Product name: 2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 10G
Price: $7882.88
Updated: 2021/12/16

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1-Indanone-6-carboxylic acid Chemical Properties,Usage,Production

Synthesis

38628-51-2

60031-08-5

The general procedure for the synthesis of 1-indanone-6-carboxylic acid from 4-(2-carboxyethyl)benzoic acid is as follows: 6-carboxy-1-indanone, which is the feedstock of Example 206, was prepared as follows: 3-(4-carboxyphenyl)propionic acid (5 g, 0.026 mol), fresh AlCl3 (25 g, 7.2 equivalents, 0.187 mol) and NaCl (2.5 g , 10% of the mass of AlCl3) were added to a 100 mL flask equipped with a condenser and an internal thermometer. The flask was shaken briefly to mix the solids well and subsequently heated in an oil bath set at 190°C. The reaction was maintained at an internal temperature of 180°C or above for 1 hour (the mixture melted to a dark brown liquid during the reaction). After the reaction was complete, the mixture was cooled and poured into a 2000 mL beaker containing ice and washed with water. 180mL of 6M HCl and 250mL of EtOAc were added and the layers were separated. The aqueous layer was extracted with EtOAc (3 x 200mL). The organic layers were combined, washed sequentially with 2M HCl, water and brine, dried with MgSO4, filtered and concentrated in vacuum to give a light brown solid 6-carboxy-1-indanone (4.10 g, 90% yield), which was used directly in the next synthesis.

References

[1] Patent: WO2005/87236, 2005, A1. Location in patent: Page/Page column 39
[2] Patent: US2010/249095, 2010, A1. Location in patent: Page/Page column 68-69
[3] Tetrahedron, 1995, vol. 51, # 1, p. 203 - 216
[4] Journal of the Chemical Society, 1956, p. 4647,3652
[5] Patent: US2012/71461, 2012, A1. Location in patent: Page/Page column 60

1-Indanone-6-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Indanone-6-carboxylic acid Suppliers

Austria 1 China 69 Germany 1 India 2 Switzerland 1 United Kingdom 2 United States 14 Global 90

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View Lastest Price from 1-Indanone-6-carboxylic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 1-Indanone-6-carboxylic acid 60031-08-5
Price: US $0.10-10.00/KG
Min. Order: 0.10000000149011612KG
Purity: 98%
Supply Ability: 200TONS
Release date: 2025-08-14

Career Henan Chemical Co

Product: 1-Indanone-6-carboxylic acid 60031-08-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KGS
Release date: 2019-12-25

60031-08-5, 1-Indanone-6-carboxylic acidRelated Search:

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6-CARBOXY-1-INDANONE

3-OXO-INDAN-5-CARBOXYLIC ACID

3-OXOINDANE-5-CARBOXYLIC ACID

2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID

1-INDANONE-6-CARBOXYLIC ACID

6-CARBOXYLIC ACID 1-INDANONE

3-oxo-2,3-dihydro-1H-indene-5-carboxylic acid

JR-8361, 2,3-Dihydro-3-oxo-1H-indene-5-carboxylic acid, 97%

3-oxo-1,2-dihydroindene-5-carboxylic Acid

1H-Indene-5-carboxylic acid, 2,3-dihydro-3-oxo-

60031-08-5

pharmacetical

Benzocycles