2-Bromo-5-methylthiophene

Uses

Product Name: 2-Bromo-5-methylthiophene
CAS No.: 765-58-2
Chemical Name: 2-Bromo-5-methylthiophene
Synonyms: 2-Bromo-5-methylthio;bromomethylthiophene;2-BROMO-5-METHYLTHIOPHENE;5-Methyl-2-bromothiophene;5-Bromo-2-methylthiophene;2-BROMO-5-METHYLTHIOPHENOL;Thiophene, 2-bromo-5-methyl-;2-BROMO-5-METHYLTHIOPHENE,96%;2-BroMo-5-Methylthiophene, 95+%;2-Bromo-5-methylthiophene ISO 9001：2015 REACH
CBNumber: CB4684448
Molecular Formula: C5H5BrS
Formula Weight: 177.06
MOL File: 765-58-2.mol

More

Less

2-Bromo-5-methylthiophene Property

Boiling point:: 65 °C/15 mmHg (lit.)
Density: 1.552 g/mL at 25 °C (lit.)
refractive index: n20/D 1.569(lit.)
Flash point:: 173 °F
storage temp.: 2-8°C
form: Liquid Which May Contain Some Precipitate
Specific Gravity: 1.552
color: Yellow
InChI: InChI=1S/C5H5BrS/c1-4-2-3-5(6)7-4/h2-3H,1H3
InChIKey: ACDLOOGOFKSUPO-UHFFFAOYSA-N
SMILES: C1(Br)SC(C)=CC=1
CAS DataBase Reference: 765-58-2(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 23-36/37/39-37/39-26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 515485
Product name: 2-Bromo-5-methylthiophene
Purity: 95%
Packaging: 1g
Price: $36.7
Updated: 2022/05/15

TCI Chemical

Product number: B1540
Product name: 2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3)
Purity: >98.0%(GC)
Packaging: 5g
Price: $30
Updated: 2025/07/31

TCI Chemical

Product number: B1540
Product name: 2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3)
Purity: >98.0%(GC)
Packaging: 25g
Price: $118
Updated: 2025/07/31

TRC

Product number: B697805
Product name: 2-Bromo-5-methylthiophene
Packaging: 1g
Price: $45
Updated: 2021/12/16

TRC

Product number: B697805
Product name: 2-Bromo-5-methylthiophene
Packaging: 5g
Price: $55
Updated: 2021/12/16

More

Less

2-Bromo-5-methylthiophene Chemical Properties,Usage,Production

Uses

2-Bromo-5-methylthiophene is a heterocyclic compound that can be used as an intermediate in organic synthesis.

Chemical Properties

Yellow liquid

Synthesis

554-14-3

765-58-2

General procedure for the synthesis of 2-bromo-5-methylthiophene from 2-methylthiophene: A bromine solution was prepared by dissolving 48.0 g of bromine (0.3 mol) in 260 cm3 dioxane. This bromine solution was slowly added dropwise under stirring conditions to a solution of 29.4 g 2-methylthiophene (0.3 mmol) dissolved in 140 cm3 dioxane. The reaction mixture was stirred continuously for 3 hours at room temperature. Subsequently, the reaction system was cooled to 0 °C and saturated aqueous sodium bicarbonate solution was carefully added to neutralize the reaction. The mixture was extracted with ethyl acetate and the organic layer was separated. The organic layer was dried over anhydrous sodium sulfate and evaporated under reduced pressure to remove the solvent. The residue was purified by distillation to give 37.2 g 2-bromo-5-methylthiophene (0.21 mol, 70% yield). Boiling point: 68-70 °C (20 mbar). 1H NMR (400 MHz, CDCl3): δ = 2.42 (s, 3H), 6.51 (d, 1H, J = 3.6 Hz), 6.83 (d, 1H, J = 3.6 Hz) ppm. LC-MS: retention time tR = 1.65 min; MS: m/z = 176, 178 ([M+ 1]+, [M+3]+).

References

[1] Journal of Organic Chemistry, 2014, vol. 79, # 4, p. 1836 - 1841
[2] Synthesis, 2002, # 9, p. 1133 - 1135
[3] Green Chemistry, 2018, vol. 20, # 19, p. 4448 - 4452
[4] Synthesis, 2011, # 2, p. 207 - 209
[5] European Journal of Organic Chemistry, 2018, vol. 2018, # 20, p. 2592 - 2602

2-Bromo-5-methylthiophene Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Bromo-5-methylthiophene Suppliers

Americas 1 Canada 2 China 200 Europe 1 France 1 Germany 4 India 5 Japan 3 Slovakia 2 Switzerland 1 Ukraine 1 United Kingdom 14 United States 29 Global 264

Aobolihui

Tel: 0917-18691729 18691729963
Email: 2553382659@qq.com
Country: China
ProdList: 4739
Advantage: 58

Hangzhou Copiore Chemical Co., Ltd.

Tel: 0571-56501939;0571-56076030 13757145729
Fax: 0571-56501939
Email: sales@copiore.com
Country: China
ProdList: 299
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

More

Less

View Lastest Price from 2-Bromo-5-methylthiophene manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 2-Bromo-5-methylthiophene 765-58-2
Price: US $0.00-0.00/KS
Min. Order: 1KS
Purity: 98%
Supply Ability: 2000
Release date: 2025-04-18

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Bromo-5-methylthiophene 765-58-2
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-05

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2-Bromo-5-methylthiophene 765-58-2
Price: US $200.00-95.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-22

765-58-2, 2-Bromo-5-methylthiopheneRelated Search:

Benzyl bromide 3-Bromoanisole Cyclohexylmethyl bromide BROMOPENTAMETHYLBENZENE Bromotrimethylsilane 2-Bromothiophene Methyl bromide Bromine METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE 2,3,4-Tribromo-5-methylthiophene 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME 2-BROMO-5-PHENYLTHIOPHENE 2-(5-BROMO-2-THIENYL)-3-CHLOROQUINOXALINE 2-Acetyl-5-bromothiophene 2-(5-BROMO-2-THIENYL)PYRIDINE 5-Bromothiophene-2-carbaldehyde 3-(5-BROMO-2-THIENYL)ISOXAZOLE 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID

2-BROMO-5-METHYLTHIOPHENE,96%

2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3)

2-Bromo-5-methylthio

2-Bromo-5-methylthiophene, stabilised with Copper (0.1%) and Sodium bicarbonate (0.4%), 95%

2-BROMO-5-METHYLTHIOPHENOL

5-Bromo-2-methylthiophene

5-Methyl-2-bromothiophene

2-BroMo-5-Methylthiophene, 95+%

2-BROMO-5-METHYLTHIOPHENE

bromomethylthiophene

2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3)&gt

Thiophene, 2-bromo-5-methyl-

2-Bromo-5-methylthiophene ISO 9001：2015 REACH

765-58-2

Thiophenes

Halogenated Heterocycles

Heterocyclic Building Blocks

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Thiophenes

ThiophenesBuilding Blocks

Azoles

blocks

Bromides

Sulphur Derivatives

Thiophene&Benzothiophene

Thiophens

Heterocycle-oher series