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S-ADENOSYL-L-METHIONINE CHLORIDE SALT

Product Name
S-ADENOSYL-L-METHIONINE CHLORIDE SALT
CAS No.
24346-00-7
Chemical Name
S-ADENOSYL-L-METHIONINE CHLORIDE SALT
Synonyms
SAM-Cl;SAM CHLORIDE;Einecs 246-184-8;ACTIVE METHIONINE;SAM-E CHLORIDE SALT;ADEMETHIONINECHLORIDE;Active methionine chloride;S-ADENOSYL-L-METHIONINE CHLORIDE;ADENOSYL-L-METHIONINE CHLORIDE, S-;S-ADENOSYL METHIONINE CHLORIDE SALT
CBNumber
CB4723189
Molecular Formula
C15H23ClN6O5S
Formula Weight
434.9
MOL File
24346-00-7.mol
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S-ADENOSYL-L-METHIONINE CHLORIDE SALT Property

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O: 100 mg/mL
form 
Solid
color 
Off-White to Dark Yellow
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-68/20/21/22
Safety Statements 
36-45
WGK Germany 
1
F 
10-21
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
AAA0004890
Product name
S-(5'-ADENOSYL)-L-METHIONINE CHLORIDE
Purity
95.00%
Packaging
5MG
Price
$501.88
Updated
2021/12/16
Matrix Scientific
Product number
097918
Product name
5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride
Purity
95+%
Packaging
250mg
Price
$515
Updated
2021/12/16
AK Scientific
Product number
1800AB
Product name
5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosinechloride
Packaging
250mg
Price
$745
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0004890
Product name
S-(5'-ADENOSYL)-L-METHIONINE CHLORIDE
Purity
95.00%
Packaging
250MG
Price
$877.8
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
19369
Product name
S-(5?-Adenosyl)-L-methionineChloride
Packaging
1g
Price
$990
Updated
2021/12/16
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S-ADENOSYL-L-METHIONINE CHLORIDE SALT Chemical Properties,Usage,Production

Purification Methods

Purify it by ion exchange on Amberlite IRC-150 and eluting with 0.1-4M HCl. [Stolowitz & Minch J Am Chem Soc 103 6015 1981.] It has been isolated as the tri-reineckate salt by adding 2volumes of 1% solution of ammonium reineckate in 2% perchloric acid. The reineckate salt separates at once but is kept at 2o overnight. The salt is collected on a sintered glass funnel, washed with 0.5% of ammonium reineckate, dried (all operations at 2o) and stored at 2o. To obtain adenosylmethionine, the reineckate is dissolved in a small volume of methyl ethyl ketone (MEK) and centrifuged at room temperature to remove a small amount of solid. The clear dark red supernatant is extracted (in a separating funnel) with a slight excess of 0.1N H2SO4. The aqueous phase is re-extracted with fresh MEK until it is colourless. [Note that reineckates have UV absorption at 305nm ( 15,000), and the optical density at 305nm is used to detect and estimate reineckate ions.] MEK is removed from the aqueous layer containing adenosylmethionine sulfate; the pH is adjusted to 5.6-6.0 and extracted with two volumes of Et2O. The sulfate is obtained by evaporating the aqueous layer in vacuo. The hydrochloride can be obtained in the same way but using HCl instead of H2SO4. SAM-HCl has a solubility of 10% in H2O. The salts are stable in the cold at pH 4-6 but decompose in alkaline media. [Cantoni Biochemical Preparations 5 58 1957.] The purity of SAM can be determined by paper chromatography [Cantoni J Biol Chem 204 403 1953, Methods Enzymol 3 601 1957], electrophoretic methods or enzymic analysis [Cantoni & Vignos J Biol Chem 209 647 1954]. [Beilstein 26 III/IV 3676.]

S-ADENOSYL-L-METHIONINE CHLORIDE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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S-ADENOSYL-L-METHIONINE CHLORIDE SALT Suppliers

Canada 1 China 41 Europe 2 Germany 1 Japan 1 Switzerland 1 United Kingdom 1 United States 8 Global 56
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from S-ADENOSYL-L-METHIONINE CHLORIDE SALT manufacturers

Career Henan Chemical Co
Product
S-ADENOSYL-L-METHIONINE CHLORIDE SALT 24346-00-7
Price
US $1.00/g
Min. Order
100g
Purity
>98%
Supply Ability
g/kg/Ton
Release date
2020-01-14

24346-00-7, S-ADENOSYL-L-METHIONINE CHLORIDE SALTRelated Search:

S-ADENOSYL-L-METHIONINE P-TOLUENESULFONATE SALT S-ADENOSYL-L-METHIONINE IODIDE SALT S-Adenosyl-L-methionine S-ADENOSYL-L-METHIONINE DISULFATE TOSYLATE USP/EP/BP L-Methioninol L-Methionine DL-METHIONINE METHYLSULFONIUM CHLORIDE DL-METHIONINE METHYLSULFONIUM CHLORIDE Adenine Sulfate 4-(METHYLTHIO)BUTANOL D,L-BUTHIONINE DL-ETHIONINE 5'-DEOXY-5'-METHYLTHIOADENOSINE 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE L-ETHIONINE 3-Mercapto-1,2-propanediol Adenine hydrochloride hemihydrate Adenine hydrochloride

  • SAM-E CHLORIDE SALT
  • SAM CHLORIDE
  • ACTIVE METHIONINE
  • ADENOSYL-L-METHIONINE, S-CHLORIDE SALT
  • (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfaniumyl)butanoate hydrochloride
  • S-ADENOSYL-L-METHIONINE CHLORIDE
  • S-ADENOSYL-L-METHIONINE CHLORIDE SALT
  • S-ADENOSYL METHIONINE CHLORIDE SALT
  • S-(5'-ADENOSYL)-L-METHIONINE CHLORIDE
  • (3S)-5'-[(3-amino-3-carboxypropyl)methylsulphonio]-5'-deoxyadenosine chloride
  • S-Adenosyl-5'-L-MethionineChlorideEx
  • ADEMETHIONINECHLORIDE
  • Active methionine, AdoMet, SAM chloride
  • Active methionine chloride
  • S-Adenosyl-5'-L-methionine chloride
  • Einecs 246-184-8
  • ADENOSYL-L-METHIONINE CHLORIDE, S-(RG)
  • S-(5′-Adenosyl)-L-methionine chloride,Active methionine, AdoMet, SAM chloride
  • 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride
  • SAM-Cl
  • S-ADENOSYL-L-METHIONINE CHLORIDE SALT USP/EP/BP
  • ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride
  • (2S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate hydrochloride
  • ADENOSYL-L-METHIONINE CHLORIDE, S-
  • 24346-00-7
  • C15H23ClN6O5S
  • C15H23N6O5SCl
  • Enzyme Cofactor
  • BioChemical
  • Cancer Research
  • Chemopreventive Agents
  • Amino Acids & Derivatives
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Nucleotides
  • Sulfur & Selenium Compounds