4-Chlorobutanal diethyl acetal
- Product Name
- 4-Chlorobutanal diethyl acetal
- CAS No.
- 6139-83-9
- Chemical Name
- 4-Chlorobutanal diethyl acetal
- Synonyms
- NSC 96467;4-CHLOROBUTANAL DIETHYL;4-neoprene diethyl acetal;4-Chloro-1,1-dethoxybutane;4-CHLORO-1,1-DIETHOXY BUTANE;Butane,4-chloro-1,1-diethoxy-;4-CHLORO BUTANAL DIETHYL ACETAL;4-chlorobutyraldehyde diethy acetal;5-chloro-2-(1-ethoxypropoxy)pentanal;4-CHLOROBUTYLRALDEHYDE DIETHYLACETAL
- CBNumber
- CB4726908
- Molecular Formula
- C8H17ClO2
- Formula Weight
- 180.67
- MOL File
- 6139-83-9.mol
4-Chlorobutanal diethyl acetal Property
- Boiling point:
- 208.6°C
- Density
- 0.976
- refractive index
- 1.4260-1.4300
- Flash point:
- 51.1°C
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Clear Colourless
- CAS DataBase Reference
- 6139-83-9(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- RIDADR
- 1993
- HS Code
- 2933.39.9200
- HazardClass
- 3
- PackingGroup
- III
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C2717
- Product name
- 4-Chlorobutyraldehyde Diethyl Acetal
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- C2717
- Product name
- 4-Chlorobutyraldehyde Diethyl Acetal
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $136
- Updated
- 2025/07/31
- Product number
- C365051
- Product name
- 4-Chlorobutyraldehyde Diethyl Acetal
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 074938
- Product name
- 4-Chlorobutyraldehyde diethyl acetal
- Purity
- 95+%
- Packaging
- 10g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- J90287
- Product name
- 4-Chlorobutanaldiethylacetal
- Packaging
- 5g
- Price
- $25
- Updated
- 2021/12/16
4-Chlorobutanal diethyl acetal Chemical Properties,Usage,Production
Chemical Properties
Colourless Liquid
Uses
4-Chlorobutyraldehyde Diethyl Acetal (cas# 6139-83-9) is a compound useful in organic synthesis. It is used in preparation of Fendiline derivatives as KRAS modulators.
Uses
intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan
Synthesis
64-17-5
763101-16-2
6139-83-9
The general procedure for the synthesis of 4-chlorobutanal diethyl acetal from ethanol and the compound (CAS: 763101-16-2) is as follows: preparation of 4-chlorobutanal diethyl acetal: 13.7 g (0.092 mol) of 4-chloro-1-acetoxy-1-butene, 100 ml (1.70 mol) of 95% ethanol, and about 5 g of triethyl orthoformate were mixed (triethyl orthoformate was added to ensure that the reaction proceeds under anhydrous conditions). Subsequently, 1.40 g of Amberlyst 15 catalyst was added and stirred under reflux conditions for 5 hours. Completion of the reaction was confirmed by gas chromatography (GC) analysis. Upon completion of the reaction, it was manipulated and distilled according to conventional methods to give 10.82 g (65% yield) of the product with a boiling point of 45-50 °C (1 mmHg). Nuclear magnetic resonance (NMR) analysis confirmed that the resulting product was pure 4-chlorobutanal diethyl acetal.
References
[1] Organic Preparations and Procedures International, 2004, vol. 36, # 5, p. 487 - 490
[2] Patent: US2004/192958, 2004, A1. Location in patent: Page 3-4
4-Chlorobutanal diethyl acetal Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chlorobutanal diethyl acetal manufacturers
- Product
- 4-Chlorobutanal diethyl acetal 6139-83-9
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-22
- Product
- 4-Chlorobutanal diethyl acetal 6139-83-9
- Price
- US $100.00/KG
- Min. Order
- 100G
- Purity
- 98%
- Supply Ability
- 100g,1KG,5KG,10KG
- Release date
- 2018-07-25