ChemicalBook > CAS DataBase List > 4-Chlorobutanal diethyl acetal

4-Chlorobutanal diethyl acetal

Product Name
4-Chlorobutanal diethyl acetal
CAS No.
6139-83-9
Chemical Name
4-Chlorobutanal diethyl acetal
Synonyms
NSC 96467;4-CHLOROBUTANAL DIETHYL;4-neoprene diethyl acetal;4-Chloro-1,1-dethoxybutane;4-CHLORO-1,1-DIETHOXY BUTANE;Butane,4-chloro-1,1-diethoxy-;4-CHLORO BUTANAL DIETHYL ACETAL;4-chlorobutyraldehyde diethy acetal;5-chloro-2-(1-ethoxypropoxy)pentanal;4-CHLOROBUTYLRALDEHYDE DIETHYLACETAL
CBNumber
CB4726908
Molecular Formula
C8H17ClO2
Formula Weight
180.67
MOL File
6139-83-9.mol
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4-Chlorobutanal diethyl acetal Property

Boiling point:
208.6°C
Density 
0.976
refractive index 
1.4260-1.4300
Flash point:
51.1°C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
color 
Clear Colourless
CAS DataBase Reference
6139-83-9(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
RIDADR 
1993
HS Code 
2933.39.9200
HazardClass 
3
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2717
Product name
4-Chlorobutyraldehyde Diethyl Acetal
Purity
>97.0%(GC)
Packaging
5g
Price
$42
Updated
2025/07/31
TCI Chemical
Product number
C2717
Product name
4-Chlorobutyraldehyde Diethyl Acetal
Purity
>97.0%(GC)
Packaging
25g
Price
$136
Updated
2025/07/31
TRC
Product number
C365051
Product name
4-Chlorobutyraldehyde Diethyl Acetal
Packaging
1g
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20211
Product name
4-Chlorobutyraldehyde diethyl acetal
Packaging
25g
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20211
Product name
4-Chlorobutyraldehyde diethyl acetal
Packaging
50g
Price
$130
Updated
2021/12/16
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4-Chlorobutanal diethyl acetal Chemical Properties,Usage,Production

Chemical Properties

Colourless Liquid

Uses

4-Chlorobutyraldehyde Diethyl Acetal (cas# 6139-83-9) is a compound useful in organic synthesis. It is used in preparation of Fendiline derivatives as KRAS modulators.

Uses

intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan

Synthesis

64-17-5

763101-16-2

6139-83-9

The general procedure for the synthesis of 4-chlorobutanal diethyl acetal from ethanol and the compound (CAS: 763101-16-2) is as follows: preparation of 4-chlorobutanal diethyl acetal: 13.7 g (0.092 mol) of 4-chloro-1-acetoxy-1-butene, 100 ml (1.70 mol) of 95% ethanol, and about 5 g of triethyl orthoformate were mixed (triethyl orthoformate was added to ensure that the reaction proceeds under anhydrous conditions). Subsequently, 1.40 g of Amberlyst 15 catalyst was added and stirred under reflux conditions for 5 hours. Completion of the reaction was confirmed by gas chromatography (GC) analysis. Upon completion of the reaction, it was manipulated and distilled according to conventional methods to give 10.82 g (65% yield) of the product with a boiling point of 45-50 °C (1 mmHg). Nuclear magnetic resonance (NMR) analysis confirmed that the resulting product was pure 4-chlorobutanal diethyl acetal.

References

[1] Organic Preparations and Procedures International, 2004, vol. 36, # 5, p. 487 - 490
[2] Patent: US2004/192958, 2004, A1. Location in patent: Page 3-4

4-Chlorobutanal diethyl acetal Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chlorobutanal diethyl acetal Suppliers

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View Lastest Price from 4-Chlorobutanal diethyl acetal manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Chlorobutanal diethyl acetal 6139-83-9
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
Career Henan Chemical Co
Product
4-Chlorobutanal diethyl acetal 6139-83-9
Price
US $100.00/KG
Min. Order
100G
Purity
98%
Supply Ability
100g,1KG,5KG,10KG
Release date
2018-07-25

6139-83-9, 4-Chlorobutanal diethyl acetalRelated Search:

Bromoacetaldehyde diethyl acetal Diethyl malonate Diethanolamine 2,2-Diethoxyethylamine GLYCOLALDEHYDE Polychloroprene 4-Chlorobutanal dimethyl acetal Acetal Difluorochloromethane 2-Dimethylaminoethanol Diethyl ether Sumatriptan Sucralose SUCRALOSE-D6 N-BUTANE 4-Chlorobutanal diethyl acetal 2,6-DICHLORO-ALPHA-D-GAL(1-3)-BETA-D-GAL-1-OGR 8-METHOXYCARBONYLOCTYL 4,6-DICHLORO-4,6-DIDEOXY-3-O-SULFO-BETA-D-GALACTOPRANOSYL-(1-4)-[2,3,4-TRI-O-BENZYL-ALPHA-L-FUCOPYRANOSYL (1-3)]-2-ACETAMIDO-6-O-BENZYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE

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  • 6139-83-9 4-Chlorobutanal diethyl acetal
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