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Ethyl 3-phenylpropionate

Product Name
Ethyl 3-phenylpropionate
CAS No.
2021-28-5
Chemical Name
Ethyl 3-phenylpropionate
Synonyms
Ethyl 3-phenylpropanoate;ETHYL DIHYDROCINNAMATE;ETHYL HYDROCINNAMATE;3- benzenepropanoate;3-Ethyl phenylpropionate;ethylphenylpropionate;ethylphenyl propanoate;FEMA 2455;3-phenylpentanoate;RARECHEM AL BI 0160
CBNumber
CB4744955
Molecular Formula
C11H14O2
Formula Weight
178.23
MOL File
2021-28-5.mol
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Ethyl 3-phenylpropionate Property

Melting point:
122-124 °C
Boiling point:
247-248 °C(lit.)
Density 
1.01 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.494(lit.)
FEMA 
2455 | ETHYL 3-PHENYLPROPIONATE
Flash point:
226 °F
storage temp. 
2-8°C
solubility 
Chloroform (Soluble), DMSO (Slightly), Methanol
form 
Oil
color 
Colourless
Specific Gravity
1.013
Odor
at 100.00 %. hyacinth rose honey fruity rum
Odor Type
floral
Water Solubility 
<0.1 g/100 mL at 25 ºC
JECFA Number
644
BRN 
1910432
InChIKey
JAGZUIGGHGTFHO-UHFFFAOYSA-N
LogP
2.79
CAS DataBase Reference
2021-28-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzenepropanoic acid, ethyl ester(2021-28-5)
EPA Substance Registry System
Ethyl 3-phenylpropionate (2021-28-5)
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29163900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
284416
Product name
Ethyl hydrocinnamate
Purity
99%
Packaging
25g
Price
$41.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W245518
Product name
Ethyl 3-Phenylpropionate
Purity
≥98%, FG
Packaging
sample
Price
$59.8
Updated
2023/01/07
TCI Chemical
Product number
P1304
Product name
Ethyl 3-Phenylpropionate
Purity
>98.0%(GC)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
P1304
Product name
Ethyl 3-Phenylpropionate
Purity
>98.0%(GC)
Packaging
250g
Price
$237
Updated
2024/03/01
Alfa Aesar
Product number
A13055
Product name
Ethyl 3-phenylpropionate, 98+%
Packaging
50g
Price
$57.65
Updated
2024/03/01
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Ethyl 3-phenylpropionate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Chemical Properties

Ethyl 3-phenylpropionate has an ethereal, rum, fruity, floral odor.

Occurrence

Reported found in rum, passion fruit, plum brandy, caja fruit (Spondias lutea L.) and checkur (Alpinia sessilis).

Uses

Ethyl 3-phenylpropionate is used as an active pharmaceutical ingredient intermediate. It is also used in the synthesis of pyrimidine based inhibitors of cyclin-dependant kinases.

Definition

ChEBI: Ethyl 3-phenylpropanoate is a fatty acid ester.

Preparation

By hydrogenation of the corresponding ethyl cinnamate in the presence of nickel in alcohol solution.

Aroma threshold values

Detection: 17 to 40 ppb

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 3406, 1985 DOI: 10.1021/jo00218a033
Synthetic Communications, 22, p. 2683, 1992 DOI: 10.1080/00397919208021668
Tetrahedron Letters, 42, p. 781, 2001 DOI: 10.1016/S0040-4039(00)02176-6

General Description

Clear colorless liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Ethyl 3-phenylpropionate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

The flash point of Ethyl 3-phenylpropionate has not been determined. but Ethyl 3-phenylpropionate is probably combustible.

Synthesis

Ethyl 3-phenylpropionate is synthesized by Hydrocinnamic acid and Ethanol by normal esterification.

Ethyl 3-phenylpropionate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 3-phenylpropionate Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from Ethyl 3-phenylpropionate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl 3-phenylpropionate 2021-28-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
Ethyl 3-phenylpropionate 2021-28-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-23
JINING XINHE CHEMICAL CO., LTD
Product
Ethyl 3-phenylpropionate 2021-28-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
10ton
Release date
2024-07-18

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