3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 885271-25-0
- Chemical Name
- 3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- Methyl 3-iodoindazole-5-c...;Methyl 3-iodoindazole-5-carboxylate;3-Iodo-5-(methoxycarbonyl)-1H-indazole;Methyl 3-iodo-1H-indazole-7-carboxylate;Methyl 3-iodo-1H-indazole-5-carboxylate;3-IODO-5-INDAZOLECARBOXYLIC ACID METHYL ESTER;1H-Indazole-5-carboxylicacid,3-iodo-,Methylester;3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER
- CBNumber
- CB4749884
- Molecular Formula
- C9H7IN2O2
- Formula Weight
- 302.07
- MOL File
- 885271-25-0.mol
3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER Property
- Boiling point:
- 421.4±25.0 °C(Predicted)
- Density
- 1.948
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 10.85±0.40(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
N-Bromosuccinimide Price
- Product number
- M219328
- Product name
- Methyl3-Iodo-1H-indazole-5-carboxylate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 4H23-H-X3
- Product name
- Methyl 3-iodo-1H-indazole-5-carboxylate
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 068462
- Product name
- Methyl 3-iodoindazole-5-carboxylate
- Purity
- >95%
- Packaging
- 5g
- Price
- $1554
- Updated
- 2021/12/16
- Product number
- M11197
- Product name
- Methyl3-iodo-1H-indazole-5-carboxylate
- Purity
- 98%
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 4H23-H-X3
- Product name
- Methyl 3-iodo-1H-indazole-5-carboxylate
- Packaging
- 1g
- Price
- $232
- Updated
- 2021/12/16
3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
473416-12-5
885271-25-0
GENERAL METHOD: To a cooled DMF solution, methyl 1H-indazole-5-carboxylate (1.0 eq.), K2CO3 or KOH (ca. 3 eq.), and I2 (2-4 eq.) were sequentially added at 0 °C. The reaction mixture was stirred under cooling conditions or at room temperature for several hours. Upon completion of the reaction, the reaction is quenched with an excess of 10% aqueous NaHSO3, followed by dilution with H2O. In most cases, the precipitate is collected by filtration and washed with H2O to give methyl 3-iodo-5-indazolecarboxylate of the desired purity.
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 17, p. 4968 - 4997
[2] Patent: WO2017/136395, 2017, A1. Location in patent: Page/Page column 197
[3] Patent: WO2006/86255, 2006, A2. Location in patent: Page/Page column 85; 86
[4] Patent: WO2017/35349, 2017, A1. Location in patent: Paragraph 0539
3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 3-IODO-1H-INDAZOLE-5-CARBOXYLIC ACID METHYL ESTER 885271-25-0
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-08-05