ChemicalBook > CAS DataBase List > 5-METHYLPYRIMIDIN-4-OL

5-METHYLPYRIMIDIN-4-OL

Product Name
5-METHYLPYRIMIDIN-4-OL
CAS No.
17758-52-0
Chemical Name
5-METHYLPYRIMIDIN-4-OL
Synonyms
5-methyl-4-pyrimidino;5-Methyl-4-pyrimidinol;5-METHYLPYRIMIDIN-4-OL;5-Methyl-3H-pyrimidin-4-one;5-methylpyrimidin-4(3H)-one;5-methyl-1H-pyrimidin-6-one;4-Hydroxy-5-methylpyrimidine;4(3H)-Pyrimidinone,5-methyl-;5-Methyl-4-hydroxypyrimidine;5-Methylpyrimidin-4-Ol(WX649072)
CBNumber
CB4766980
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
17758-52-0.mol
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5-METHYLPYRIMIDIN-4-OL Property

Melting point:
153-154 °C
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
9.18±0.40(Predicted)
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C5H6N2O/c1-4-2-6-3-7-5(4)8/h2-3H,1H3,(H,6,7,8)
InChIKey
SHLJOANTPJWIHS-UHFFFAOYSA-N
SMILES
C1=NC=C(C)C(=O)N1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
H939883
Product name
4-Hydroxy-5-methylpyrimidine
Packaging
500mg
Price
$155
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
38027
Product name
4-Hydroxy-5-methylpyrimidine
Purity
95+%
Packaging
250mg
Price
$432
Updated
2021/12/16
Apolloscientific
Product number
OR322927
Product name
5-Methylpyrimidin-4-ol
Packaging
500mg
Price
$482
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-0HS
Product name
5-Methylpyrimidin-4-ol
Packaging
500mg
Price
$532
Updated
2021/12/16
Matrix Scientific
Product number
177091
Product name
5-Methyl-4-pyrimidinol
Packaging
1g
Price
$540
Updated
2021/12/16
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5-METHYLPYRIMIDIN-4-OL Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 296, 1984 DOI: 10.1021/jo00176a015

Synthesis

636-26-0

17758-52-0

General procedure for the synthesis of 5-methylpyrimidin-4-ol from 4-hydroxy-2-mercapto-5-methylpyrimidine: 4-hydroxy-2-mercapto-5-methylpyrimidine (1.0 g, 7.0 mmol) was suspended in water (50 mL) and ammonia (3 mL) followed by addition of nickel ruanne suspension in water (20 mL). The reaction mixture was heated to reflux for 16 h. Upon completion of the reaction, the filtrate was thermally filtered through diatomaceous earth (10 g) and the filtrate was washed with water (3 x 25 mL). The filtrate was evaporated and concentrated and the resulting solid was azeotropically dried with toluene (2 x 50 mL) to give the final white solid product 5-methylpyrimidin-4-ol (0.75 g, 97% yield).

References

[1] Patent: WO2010/41054, 2010, A1. Location in patent: Page/Page column 40-41

5-METHYLPYRIMIDIN-4-OL Preparation Products And Raw materials

Raw materials

ZINC Ethyl 2-bromopropionate Ethanol Acetone Sodium sulfate Triethyl orthoformate Toluene Sodium Diethyl ether RANEY NICKEL Iodine Hydrochloric acid Sodium bicarbonate Acetic acid Methanol Activated carbon Thiourea Ammonia

Preparation Products

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View Lastest Price from 5-METHYLPYRIMIDIN-4-OL manufacturers

Dideu Industries Group Limited
Product
5-METHYLPYRIMIDIN-4-OL 17758-52-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-METHYLPYRIMIDIN-4-OL 17758-52-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-METHYLPYRIMIDIN-4-OL 17758-52-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

17758-52-0, 5-METHYLPYRIMIDIN-4-OLRelated Search:

2-AMINO-4,6-DIHYDROXY-5-METHYLPYRIMIDINE BUPIRIMATE 5-CARBETHOXY-2-THIOURACIL Thymine 2,4-Dihydroxypyrimidine-5-carboxylic acid 2-AMINO-5,6-DIMETHYL-4-HYDROXYPYRIMIDINE 5-Hydroxymethyluracil Pirimicarb 2-AMINO-5-CARBOETHOXY-4-HYDROXYPYRIMIDINE ETHIRIMOL 1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER 2-methylpyrimidin-5-ol,2-METHYLPYRIMIDIN-5-OL,PURITY:95% MIN(HPLC) 6-(CHLOROMETHYL)-2-[(4-METHOXYPHENOXY)METHYL]PYRIMIDIN-4-OL 2-AMINO-6-METHYLPYRIMIDIN-4-OL 6-ETHYL-2-METHYLPYRIMIDIN-4-OL 4-METHYLPYRIMIDIN-2-OL HYDROCHLORIDE 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL 4-HYDROXY-2-METHYLPYRIMIDINE

  • 5-METHYLPYRIMIDIN-4-OL
  • 5-methyl-4-pyrimidino
  • 4-Hydroxy-5-methylpyrimidine
  • 4(1H)-Pyrimidinone, 5-methyl- (9CI)
  • 5-Methyl-4-hydroxypyrimidine
  • 5-Methyl-3H-pyrimidin-4-one
  • 4(3H)-Pyrimidinone,5-methyl-
  • 5-methylpyrimidin-4(3H)-one
  • 5-Methyl-4-pyrimidinol
  • 5-methyl-1H-pyrimidin-6-one
  • 5-Methylpyrimidin-4-Ol(WX649072)
  • 5-METHYLPYRIMIDIN-4-OL ISO 9001：2015 REACH
  • 17758-52-0
  • PYRIMIDINE