Cobolimab

Product Name: Cobolimab
CAS No.: 2022215-65-0
Chemical Name: Cobolimab
Synonyms: Cobolimab;TSR-022|||GSK4069889;Cobolimab (anti-TIM-3);Research Grade Cobolimab;Research Grade Cobolimab(DHJ28401)
CBNumber: CB48081120
Formula Weight: 0
MOL File: Mol file

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Cobolimab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Cobolimab Chemical Properties,Usage,Production

Uses

Cobolimab (TSR-022) is an anti-TIM-3 monoclonal antibody. Cobolimab mediates the internalization of TIM3 with an IC50 value of 0.4464 nM. Cobolimab has potential application in solid tumors and non-small cell lung cancer (NSCLC)[1][2][3].

References

[1] Falchook G S, et al. Phase 1 trial of TIM-3 inhibitor cobolimab monotherapy and in combination with PD-1 inhibitors nivolumab or dostarlimab (AMBER)[J]. 2022.
[2] Markham A. Dostarlimab: First Approval. Drugs. 2021 Jul;81(10):1213-1219. DOI:10.1007/s40265-021-01539-5
[3] Kuang Z, et al. A novel antibody targeting TIM-3 resulting in receptor internalization for cancer immunotherapy. Antib Ther. 2020 Nov 9;3(4):227-236. DOI:10.1093/abt/tbaa022
[4] Sun CY, et al. T cell exhaustion drives osteosarcoma pathogenesis. Ann Transl Med. 2021 Sep;9(18):1447. DOI:10.21037/atm-21-3928

Cobolimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Cobolimab Suppliers

China 18 Global 18

Shanghai YuanYe Biotechnology Co., Ltd.

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2022215-65-0, CobolimabRelated Search:

Tinurilimab Vedolizumab Ibalizumab Meplazumab Enfortumab Vedotin Lirilumab bimekizumab Tamrintamab Fresolimumab Tigatuzumab

Cobolimab

Research Grade Cobolimab(DHJ28401)

TSR-022|||GSK4069889

Research Grade Cobolimab

Cobolimab (anti-TIM-3)

2022215-65-0