Tamrintamab
- Product Name
- Tamrintamab
- CAS No.
- 2148325-59-9
- Chemical Name
- Tamrintamab
- Synonyms
- Tamrintamab;Tamrintamab (anti-DPEP3);Research Grade Tamrintamab;Research Grade Tamrintamab(DHJ57402)
- CBNumber
- CB88081133
- Formula Weight
- 0
- MOL File
- Mol file
Tamrintamab Property
- form
- Liquid
- color
- Colorless to light yellow
Tamrintamab Chemical Properties,Usage,Production
Uses
Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research[1][2].
References
[1] Martín-Sabroso C, et al. Antibody-Antineoplastic Conjugates in Gynecological Malignancies: Current Status and Future Perspectives. Pharmaceutics. 2021 Oct 15;13(10):1705. DOI:10.3390/pharmaceutics13101705
[2] Wiedemeyer W R, et al. Abstract NT-113: SC-003, AN ANTIBODY-DRUG CONJUGATE TARGETING DIPEPTIDASE 3, EXHIBITS POTENT ANTI-TUMOR ACTIVITY IN PATIENT-DERIVED XENOGRAFT MODELS OF HIGH GRADE SEROUS OVARIAN CANCER[J]. Clinical Cancer Research, 2019, 25(22_Supplement): NT-113-NT-113.
Tamrintamab Preparation Products And Raw materials
Raw materials
Preparation Products
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